后Tenon囊下注射曲安奈德治疗白内障手术后黄斑囊样水肿的短期疗效观察

doi:10.3760/cma.j.cn511434-20190421-00152

科研成果详情

题名	后Tenon囊下注射曲安奈德治疗白内障手术后黄斑囊样水肿的短期疗效观察
其他题名	Short-term efficacy of sub-Tenon's injection of triamcinolone acetonide for cystoid macular edema after cataract surgery
作者	黄颖; 孙祖华; 李英姿; 刘晓玲; 林冰
发表日期	2020
发表期刊	中华眼底病杂志影响因子和分区
语种	中文
原始文献类型	学术期刊
关键词	Tenon囊曲安奈德黄斑水肿／药物疗法超声乳化白内障吸除术
其他关键词	Tenon capsule ; Triamcinolone acetonide ; Macular edema/drug therapy ; Phacoemulsification
摘要	目的观察后Tenon囊下注射曲安奈德(TA)治疗白内障手术后黄斑囊样水肿(CME)的短期临床疗效。方法回顾性临床研究。2013年10月1日至2018年10月1日于温州医科大学附属眼视光医院检查确诊的白内障手术后CME患者21例21只眼纳入研究。所有患眼均行BCVA、眼压、频域OCT检查。采用标准对数视力表行BCVA检查,记录时换算为logMAR视力。采用频域OCT仪测量黄斑中心凹视网膜厚度(CRT)。21例21只眼中,男性9例9只眼,女性12例12只眼;平均年龄(66.38±10.88)岁。其平均logMAR BCVA 0.46±0.23;平均CRT (519.90±131.59)μm;平均眼压(11.01±3.97)mmHg (1 mmHg=0.133 kPa)。所有患眼均接受后Tenon囊下注射100 mg/ml的TA悬浮液0.4 ml (含TA 40 mg)的单次治疗。治疗后平均随访时间(32.86±20.2 )d。对比观察患眼治疗前及治疗后1个月的BCVA、CRT、眼压变化,并行配对t检验。结果治疗后1个月,患眼平均logMAR BCVA、CRT、眼压分别为0.29±0.22、(307.71±35.82)μm、(14.19±6.30)mmHg;与治疗前比较,差异均有统计学意义(t=5.252、8.166、4.128,P=0.000、0.000、0.001)。21只眼中,黄斑区视网膜层间囊腔完全消退13只眼(61.90%);视网膜层间仍可见囊腔8只眼(38.1%)。出现眼压>21 mmHg者3只眼,给予降眼压药物治疗后恢复正常。结论后Tenon囊下注射TA治疗白内障手术后CME短期内可降低CRT,提高视力。
其他摘要	Objective To observe the short-term efficacy of sub-Tenon's triamcinolone acetonide(TA) in the treatment of cystoid macular edema(CME) after cataract surgery. Methods A retrospective study. From October 1, 2013 to October 1, 2018, 21 patients(21 eyes) with CME after cataract surgery diagnosed at The Affiliated Eye Hospital of Wenzhou Medical University were included in this study. All eyes underwent BCVA, intraocular pressure, frequency domain OCT examination. The standard logarithmic visual acuity chart was used for BCVA examination, which was converted into logMAR visual acuity when recorded. A frequency domain OCT instrument was used to measure the foveal retinal thickness(CRT). Among 21 eyes of 21 patients, 9 eyes were male and 12 eyes were female;the average age was 66.38± 10.88 years. The average logMAR BCVA was 0.46±0.23;the average CRT was 519.90± 131.59 µm;the average intraocular pressure was 11.01 ±3.97 mmHg(1 mmHg=0.133 kPa). All eyes underwent a single treatment of 100 mg/ml TA suspension 0.4 ml(containing TA 40 mg) under Tenon's capsule. The average follow-up time after treatment was 32.86±20.2 days. The changes of BCVA, CRT and intraocular pressure were observed 1 month after treatment. The BCVA, CRT and intraocular pressure before and after treatment were compared by paired t test. Results One month after treatment, the average logMAR BCVA, CRT, and intraocular pressure of the CME eyes were 0.29±0.22,307.71 ±35.82 µm and 14.19 ± 6.30 mmHg, respectively. Compared with those before treatment, the differences were statistically significant(t=5.252,8.166,4.128;P=0.000, 0.000,0.001). Among 21 eyes, 13 eyes(61.90%) of the retinal cysts in the macular area completely disappeared;8 eyes(38.1%) were still visible between the retinal layers. Three eyes with intraocular pressure over than 21 mmHg were treated with lowering intraocular pressure and returned to normal. Conclusion Sub-Tenon's capsular injection of TA to treat CME after cataract surgery can reduce CRT and improve vision in a short time.
ISSN	1005-1015
卷号	36 期号:08 页码:616-619
DOI	10.3760/cma.j.cn511434-20190421-00152
页数	4
收录类别	CNKI ; 万方 ; SCOPUS ; 维普 ; 北大核心 ; ISTIC ; CSCD ; PKU
学科领域	医药、卫生 ; 眼科学
URL	查看原文
CSCD记录号	CSCD:6789424
SCOPUSEID	2-s2.0-85090482833
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/25659
专题	眼视光学院（生物医学工程学院）、附属眼视光医院_眼底内科
作者单位	温州医科大学附属眼视光医院眼底内科
第一作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院_眼底内科
第一作者的第一单位	眼视光学院（生物医学工程学院）、附属眼视光医院_眼底内科
推荐引用方式 GB/T 7714	黄颖,孙祖华,李英姿,等. 后Tenon囊下注射曲安奈德治疗白内障手术后黄斑囊样水肿的短期疗效观察[J]. 中华眼底病杂志,2020,36(08):616-619.
APA	黄颖, 孙祖华, 李英姿, 刘晓玲, & 林冰. (2020). 后Tenon囊下注射曲安奈德治疗白内障手术后黄斑囊样水肿的短期疗效观察. 中华眼底病杂志, 36(08), 616-619.
MLA	黄颖,et al."后Tenon囊下注射曲安奈德治疗白内障手术后黄斑囊样水肿的短期疗效观察".中华眼底病杂志 36.08(2020):616-619.