A novel mutation of SETBP1 in atypical chronic myeloid leukemia transformed from acute myelomonocytic leukemia

doi:10.1002/ccr3.243

科研成果详情

题名	A novel mutation of SETBP1 in atypical chronic myeloid leukemia transformed from acute myelomonocytic leukemia
作者	Hu, WangQiang1; Wang, XiaoXia 1; Yang, RongRong1; Xie, YaoSheng1; Zhang, Zhuo1; Lu, Hong1; Wu, LianFeng1; Lai, MeiMei 1; Yu, Kang2
发表日期	2015-06-01
发表期刊	CLINICAL CASE REPORTS 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Acute myelomonocytic leukemia atypical chronic myeloid leukemia mutation SETBP1
其他关键词	CHRONIC NEUTROPHILIC LEUKEMIA ; CML ; MALIGNANCIES ; ACTIVATION ; DISORDERS ; NEOPLASMS ; ASXL1 ; TET2 ; CBL
摘要	To investigate an oncogenic mutation of SETBP1 in the evolution from acute myelomonocytic leukemia (M4) to secondary aCML. Clinical data and molecular studies were analyzed of paired aCML and 'normal'DNA from a case with M4. We identified a mutation in SETBP1 (encoding a p.Asp868Ala alteration). The analysis of paired sample indicated that SETBP1 mutation was acquired during leukemic evolution.
出版者	WILEY
出版地	HOBOKEN
ISSN	2050-0904
卷号	3 期号:6 页码:448-452
DOI	10.1002/ccr3.243
页数	5
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
WOS记录号	WOS:000363386400025
收录类别	ESCI ; PUBMED
URL	查看原文
PubMed ID	26185647
PMC记录号	PMC4498861
通讯作者地址	[Hu, WangQiang]Wenzhou Med Univ, Dept Lab Med, Affiliated Hosp 1, Wenzhou 325000, Zhejiang, Peoples R China.
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/2409
专题	检验医学院（生命科学学院、生物学实验教学中心）附属第一医院_血液内科
通讯作者	Hu, WangQiang
作者单位	1.Wenzhou Med Univ, Dept Lab Med, Affiliated Hosp 1, Wenzhou 325000, Zhejiang, Peoples R China; 2.Wenzhou Med Univ, Dept Hematol, Affiliated Hosp 1, Wenzhou 325000, Zhejiang, Peoples R China
第一作者单位	附属第一医院; 检验医学院（生命科学学院、生物学实验教学中心）; 检验科
通讯作者单位	附属第一医院; 检验医学院（生命科学学院、生物学实验教学中心）; 检验科
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Hu, WangQiang,Wang, XiaoXia,Yang, RongRong,et al. A novel mutation of SETBP1 in atypical chronic myeloid leukemia transformed from acute myelomonocytic leukemia[J]. CLINICAL CASE REPORTS,2015,3(6):448-452.
APA	Hu, WangQiang., Wang, XiaoXia., Yang, RongRong., Xie, YaoSheng., Zhang, Zhuo., ... & Yu, Kang. (2015). A novel mutation of SETBP1 in atypical chronic myeloid leukemia transformed from acute myelomonocytic leukemia. CLINICAL CASE REPORTS, 3(6), 448-452.
MLA	Hu, WangQiang,et al."A novel mutation of SETBP1 in atypical chronic myeloid leukemia transformed from acute myelomonocytic leukemia".CLINICAL CASE REPORTS 3.6(2015):448-452.