Therapeutic Efficacy of Re-Lin-Qing Granules in Treating Type 2 Diabetes Mellitus Complicated with Urinary Tract Infection: A Retrospective Study

doi:10.56434/j.arch.esp.urol.20247710.161

科研成果详情

题名	Therapeutic Efficacy of Re-Lin-Qing Granules in Treating Type 2 Diabetes Mellitus Complicated with Urinary Tract Infection: A Retrospective Study
作者	Shan, Zhuocheng; Shan, Feiyu; Li, Zhenxing; Yuan, Zhengzhong; Ye, Ren
发表日期	2024-12
发表期刊	ARCHIVOS ESPANOLES DE UROLOGIA 影响因子和分区
语种	英语
原始文献类型	Article
关键词	diabetes mellitus type 2 urinary tract infections retrospective studies
其他关键词	RISK
摘要	Purpose: Urinary tract infections (UTIs) frequently occur in patients with type 2 diabetes mellitus (T2DM), presenting a complex pathogenesis that significantly impairs patient quality of life. Despite the availability of various clinical treatments, challenges remain regarding their efficacy and safety. Therefore, this retrospective study aimed to observe the therapeutic effects of Re-Lin-Qing granules in treating T2DM complicated by UTIs, aiming to provide more scientifically validated and effective treatment options for clinical practice. Methods: A retrospective analysis was conducted on 115 patients with T2DM complicated by UTIs to compare the efficacy of routine treatment alone (routine group, n = 56) vs. routine treatment combined with Re-Lin-Qing granules (combined treatment group, n = 59). Baseline characteristics, UTI parameters, inflammatory marker levels, and adverse events were evaluated. Results: The combined treatment group demonstrated lower leukocyte counts in urine (120.28 +/- 30.14 cells/mu L vs. 100.23 +/- 25.16 cells/mu L, p < 0.001), a reduced percentage of positive nitrite in urine (39.29% vs. 20.34%, p = 0.043), and a lower rate of positive urine cultures (55.36% vs. 33.90%, p = 0.033) for bacteria compared to the routine group. Additionally, inflammatory marker levels, including C-reactive protein (14.68 +/- 1.25 vs. 14.15 +/- 1.09, p = 0.017) and interleukin-6 (4.29 +/- 0.81 vs. 3.97 +/- 0.75, p = 0.028), were significantly lower in the combined treatment group. The occurrence of adverse events did not differ significantly between the two groups (p > 0.05). Conclusions: The study provides evidence supporting the potential therapeutic benefits of Re-Lin-Qing granules as an adjunct therapy for T2DM complicated by UTIs. The findings indicate improvements in UTI parameters and inflammatory markers in the combined treatment group, highlighting the potential clinical benefits of incorporating Re-Lin-Qing granules into managing these comorbid conditions.
资助项目	Science and Technol-ogy Program of Traditional Chinese Medicine in Zhejiang Province [2024ZF102]
出版者	INIESTARES, S.A.
ISSN	0004-0614
EISSN	1576-8260
卷号	77 期号:10 页码:1155-1161
DOI	10.56434/j.arch.esp.urol.20247710.161
页数	7
WOS类目	Urology & Nephrology
WOS研究方向	Urology & Nephrology
WOS记录号	WOS:001392660200001
收录类别	SCIE ; SCOPUS ; PUBMED
URL	查看原文
PubMed ID	39763255
SCOPUSEID	2-s2.0-85214137829
通讯作者地址	[Ye, Ren]Wenzhou Med Univ, Affiliated Hosp 1, Dept Tradit Chinese Med, Wenzhou 325000, Zhejiang, Peoples R China.
Scopus学科分类	Urology
SCOPUS_ID	SCOPUS_ID:85214137829
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/225005
专题	附属第一医院_中医科
通讯作者	Ye, Ren
作者单位	Wenzhou Med Univ, Affiliated Hosp 1, Dept Tradit Chinese Med, Wenzhou 325000, Zhejiang, Peoples R China
第一作者单位	附属第一医院_中医科
通讯作者单位	附属第一医院_中医科
第一作者的第一单位	附属第一医院_中医科
推荐引用方式 GB/T 7714	Shan, Zhuocheng,Shan, Feiyu,Li, Zhenxing,et al. Therapeutic Efficacy of Re-Lin-Qing Granules in Treating Type 2 Diabetes Mellitus Complicated with Urinary Tract Infection: A Retrospective Study[J]. ARCHIVOS ESPANOLES DE UROLOGIA,2024,77(10):1155-1161.
APA	Shan, Zhuocheng, Shan, Feiyu, Li, Zhenxing, Yuan, Zhengzhong, & Ye, Ren. (2024). Therapeutic Efficacy of Re-Lin-Qing Granules in Treating Type 2 Diabetes Mellitus Complicated with Urinary Tract Infection: A Retrospective Study. ARCHIVOS ESPANOLES DE UROLOGIA, 77(10), 1155-1161.
MLA	Shan, Zhuocheng,et al."Therapeutic Efficacy of Re-Lin-Qing Granules in Treating Type 2 Diabetes Mellitus Complicated with Urinary Tract Infection: A Retrospective Study".ARCHIVOS ESPANOLES DE UROLOGIA 77.10(2024):1155-1161.