Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective cohort study

doi:10.3389/fneur.2024.1456884

科研成果详情

题名	Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective cohort study
作者	Lu, Rongrong1; Wu, Changcai2
发表日期	2024-11-28
发表期刊	FRONTIERS IN NEUROLOGY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	platelets to red cell distribution width ratio non-traumatic cerebral hemorrhage MIMIC-IV database all-cause mortality critically ill patients
其他关键词	RHEUMATOID-ARTHRITIS ; ANEMIA ; COUNT ; DISEASE ; STROKE ; VOLUME
摘要	Background The purpose of this study was to investigate the relationship between platelet-to-red cell distribution width ratio (PRR) and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage (NCH).Methods The Medical Information Mart for Intensive Care (MIMIC-IV) database was used to identify patients with NCH who needed to be admitted to intensive care unit (ICU). The outcomes of the study included both ICU and in-hospital mortality. Restricted cubic splines and Cox proportional hazards regression analysis were used to clarify the relationship between PRR and clinical outcomes in critically ill patients with NCH.Results A total of 3,094 patients (54.0% male) were included in the study, with in-hospital mortality and ICU mortality rates of 16.5 and 11.8%, respectively. A substantial correlation was found by multivariate Cox proportional hazards analysis between increased PRR and a lower risk of in-hospital and ICU mortality. Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96-0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96-0.99; p = 0.027). As PRR increased, restrictive cubic splines showed a progressive decrease in the probability of all-cause mortality. Stratified analyses indicated a consistent association between PRR and both in-hospital and ICU mortality.Conclusion Among critically ill patients with NCH, lower PRR was substantially correlated with the increased probability of all-cause mortality in both the ICU and hospital. According to this research, PRR might be a valuable indicator for identifying NCH patients at risk of all-cause mortality.
出版者	FRONTIERS MEDIA SA
ISSN	1664-2295
卷号	15
DOI	10.3389/fneur.2024.1456884
页数	13
WOS类目	Clinical Neurology ; Neurosciences
WOS研究方向	Neurosciences & Neurology
WOS记录号	WOS:001374612300001
收录类别	SCIE ; PUBMED
URL	查看原文
PubMed ID	39669106
通讯作者地址	[Wu, Changcai]Wenzhou Med Univ, Affiliated Hosp 1, Dept Ultrasound, Wenzhou, Zhejiang, Peoples R China.
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/223501
专题	第二临床医学院，附属第二医院、育英儿童医院_外科学_神经外科附属第一医院
通讯作者	Wu, Changcai
作者单位	1.Wenzhou Med Univ, Affiliated Hosp & Yuying Childrens Hosp 2, Dept Neurosurg, Wenzhou, Zhejiang, Peoples R China; 2.Wenzhou Med Univ, Affiliated Hosp 1, Dept Ultrasound, Wenzhou, Zhejiang, Peoples R China
第一作者单位	第二临床医学院，附属第二医院、育英儿童医院_外科学_神经外科
通讯作者单位	附属第一医院
第一作者的第一单位	第二临床医学院，附属第二医院、育英儿童医院_外科学_神经外科
推荐引用方式 GB/T 7714	Lu, Rongrong,Wu, Changcai. Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective cohort study[J]. FRONTIERS IN NEUROLOGY,2024,15.
APA	Lu, Rongrong, & Wu, Changcai. (2024). Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective cohort study. FRONTIERS IN NEUROLOGY, 15.
MLA	Lu, Rongrong,et al."Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective cohort study".FRONTIERS IN NEUROLOGY 15(2024).