Anti-hypertensive effects of NIP extract in two different rat models

科研成果详情

题名	Anti-hypertensive effects of NIP extract in two different rat models
作者	Chen, Suhong; Lv, Guiyuan; Zhang, Xiaodong; Liu, Xiaoyu; Zhang, Han; Zhu, Yunwei; Wu, Yin; Liu, Saiyue; Ni, Zhunan
会议录名称	ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION 影响因子和分区
语种	英语
原始文献类型	Article ; Proceedings Paper
会议名称	International Conference on Clinical Nutrition
会议日期	OCT 15-18, 2006
会议地点	Zhejiang Univ, Hangzhou, PEOPLES R CHINA
关键词	food aid expert system disaster relief monitoring evaluation
摘要	The aim of the study was to evaluate whether laiju extract (LJE) from Semen Raphani and Flos Chrysanthemi has an anti-hypertensive effect in renal hypertensive rat (RHR) and spontaneous hypertensive rat (SHR). LJE was prepared by extracting dried Semen Raphani and Flos Chrysanthemi with 70% ethanol. RHR and SHR models were prepared by standard methods. Forty RERs and 40 SHRs were randomly divided into high LJE (300 mg/kg), moderate LJE (200 mg/kg), low LJE (100 mg/kg) and saline control four groups (n= 10), respectively. Compared with saline control, blood pressure was significantly lowered at 6 and 5 hours in high and moderate LJE respectively in both RHR and SHR groups. However, blood pressure was significantly lowered at 2 and 3 hours in low LJE in both RHR and SHR groups, respectively. Compared with saline control, blood pressure remained significantly lower in SHR in all dosage groups with a single daily dose for 28 days of study. LJE has potential in the prevention management of hypertension. Further studies are needed to identify the active chemical constituents and mechanisms of action of LJE.
出版地	MCKINNON
出版者	H E C PRESS, HEALTHY EATING CLUB PTY LTD
ISSN	0964-7058
EISSN	1440-6047
卷号	16
页码	309-312
页数	4
WOS类目	Nutrition & Dietetics
WOS研究方向	Nutrition & Dietetics
WOS记录号	WOS:000245926500059
收录类别	CPCI
发表日期	2007-12-31
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	会议论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/22110
专题	第一临床医学院（信息与工程学院）、附属第一医院_中医学
作者单位	Zhejiang Chinese Med Univ, Inst Mat Med, Hangzhou 310053, Zhejiang, Peoples R China; Wenzhou Med Coll, Acad Tradit Chinese Med, Wenzhou, Peoples R China; State Food & Drug Adm, Ctr Drug Evaluat, Beijing, Peoples R China; Shanghai Univ Tradit Chinese Med, Shanghai, Peoples R China
第一作者单位	中医学
第一作者的第一单位	中医学
推荐引用方式 GB/T 7714	Chen, Suhong,Lv, Guiyuan,Zhang, Xiaodong,et al. Anti-hypertensive effects of NIP extract in two different rat models[C]. MCKINNON:H E C PRESS, HEALTHY EATING CLUB PTY LTD,2007:309-312.