Optimizing Antibiotic Treatment for Urinary Tract Infections Secondary to Escherichia coli in Elderly Diabetic Patients: Considering Age and Blood Glucose Control

doi:10.1159/000541435

科研成果详情

题名	Optimizing Antibiotic Treatment for Urinary Tract Infections Secondary to Escherichia coli in Elderly Diabetic Patients: Considering Age and Blood Glucose Control
作者	Yi, Baozhu1; Xu, Xiaowei 2; Lin, Zhendong1; He, Youhua3; Wang, Shuaibin3
发表日期	2024-09-16
发表期刊	UROLOGIA INTERNATIONALIS 影响因子和分区
语种	英语
原始文献类型	Article ; Early Access
关键词	Urinary tract infections Diabetes Antibiotic treatment Age and blood glucose control
摘要	Introduction: This study aimed to examine the susceptibility profile of Escherichia coli in urinary tract infections (UTIs) among elderly diabetic patients to support judicious and evidence-based antibiotic use. Methods: From January 2021 to December 2022, urine culture results were analyzed to determine the distribution of pathogens, especially E. coli, and their drug susceptibility. Results:E. coli infection was the most prevalent infection in elderly diabetic patients with UTIs, accounting for 32.6% of cases. Moreover, this bacterium's multiple resistance rate (38.3%) was significantly higher than other bacteria's multiple resistance rate (chi(2) = 81.644, p < 0.05). Compared to older diabetic patients with optimal glucose control (HbA1c <= 7.0%), patients with poor glycemic control (HbA1c >7.0%) had lower resistance rates to lactams, and urine pH values were higher (p < 0.05). Conclusion: The most common cause of UTIs is E. coli, with advanced age and diabetes being the main risk factors. To optimize UTI treatment safety and efficacy, antibiotics should be administered based on the patient's age and blood glucose control. (c) 2024 S. Karger AG, Basel
资助项目	Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project [2024ZL109]; Wenzhou Science and Technology Bureau [2023Y1105]
出版者	KARGER
ISSN	0042-1138
EISSN	1423-0399
DOI	10.1159/000541435
页数	9
WOS类目	Urology & Nephrology
WOS研究方向	Urology & Nephrology
WOS记录号	WOS:001335465800001
收录类别	SCIE
PubMed ID	39284293
通讯作者地址	[Wang, Shuaibin]Wenzhou Med Univ, Affiliated Hosp 2, Dept Urol, Yuying Childrens Hosp, Wenzhou, Peoples R China.
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/220789
专题	第二临床医学院、附属第二医院、育英儿童医院附属第二医院附属第二医院_泌尿外科第二临床医学院、附属第二医院、育英儿童医院_妇产科学
通讯作者	Wang, Shuaibin
作者单位	1.Wenzhou Med Univ, Yuying Childrens Hosp, Affiliated Hosp 2, Dept Gynecol & Obstet, Wenzhou, Peoples R China; 2.Wenzhou Med Univ, Wenzhou, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 2, Dept Urol, Yuying Childrens Hosp, Wenzhou, Peoples R China
第一作者单位	第二临床医学院，附属第二医院、育英儿童医院; 附属第二医院; 妇产科学
通讯作者单位	附属第二医院; 第二临床医学院，附属第二医院、育英儿童医院; 泌尿外科
第一作者的第一单位	第二临床医学院，附属第二医院、育英儿童医院
推荐引用方式 GB/T 7714	Yi, Baozhu,Xu, Xiaowei,Lin, Zhendong,et al. Optimizing Antibiotic Treatment for Urinary Tract Infections Secondary to Escherichia coli in Elderly Diabetic Patients: Considering Age and Blood Glucose Control[J]. UROLOGIA INTERNATIONALIS,2024.
APA	Yi, Baozhu, Xu, Xiaowei, Lin, Zhendong, He, Youhua, & Wang, Shuaibin. (2024). Optimizing Antibiotic Treatment for Urinary Tract Infections Secondary to Escherichia coli in Elderly Diabetic Patients: Considering Age and Blood Glucose Control. UROLOGIA INTERNATIONALIS.
MLA	Yi, Baozhu,et al."Optimizing Antibiotic Treatment for Urinary Tract Infections Secondary to Escherichia coli in Elderly Diabetic Patients: Considering Age and Blood Glucose Control".UROLOGIA INTERNATIONALIS (2024).