题名 | Traditional Chinese Medicine Epimedium Release from PLGA/HA Scaffolds Prepared in Supercritical CO2 |
作者 | |
发表日期 | 2012-12-31 |
会议录名称 | ADVANCED RESEARCH ON ENGINEERING MATERIALS, ENERGY, MANAGEMENT AND CONTROL, PTS 1 AND 2 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Proceedings Paper |
关键词 | Tissue engineering drug release scaffold epimedium |
其他关键词 | FABRICATION |
摘要 | Traditional chinese medicine epimedium was introduced into the poly(D,L-lactide-co-glycolide) / hydroxyapatite (PLGA/HA) scaffolds by using a supercritical CO2 technique. The morphology, porosity, mechanical strength, degradation behaviors, and drug release kenitics of scaffolds with 1 wt%, 5 wt% and 10 wt% of epimedium were determined. The results revealed that the micropores and macropores in the scaffolds were interconnect, and the addition of drug had little effect on the morphology of scaffolds. When the drug was at 10 wt%, the porosity and mechnical strength of scaffolds were deteriorated. The dosage of epimedium in scaffolds exhibits an signficant influence on weight loss of scaffolds and release kenitics of epimedium. Within the limits of our study, 5 wt% epimedium loaded scaffolds might be suitable for bone tissue egineering application. |
资助项目 | Science and technology bureau of Wenzhou City [2011S0088]; Natural Science Foundation of Zhejiang ProvinceNatural Science Foundation of Zhejiang Province [Y2110401, Y12H140011] |
出版者 | TRANS TECH PUBLICATIONS LTD |
出版地 | DURNTEN-ZURICH |
ISSN | 1022-6680 |
卷号 | 424-425 |
页码 | 48-+ |
DOI | 10.4028/www.scientific.net/AMR.424-425.48 |
页数 | 2 |
WOS类目 | Engineering, Mechanical ; Materials Science, Multidisciplinary |
WOS研究方向 | Engineering ; Materials Science |
WOS记录号 | WOS:000302663400012 |
收录类别 | CPCI ; EI |
EI入藏号 | 20120414713968 |
EI主题词 | Scaffolds (biology) |
会议名称 | 2nd International Conference on Engineering Materials, Energy, Management and Control |
会议地点 | Wuhan, PEOPLES R CHINA |
会议日期 | MAR 17-18, 2012 |
引用统计 | |
文献类型 | 会议论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/22009 |
专题 | 口腔医学院、附属口腔医院 附属第一医院_全科医学科 |
通讯作者 | Liu, Jinsong |
作者单位 | 1.Wenzhou Med Coll, Sch & Hosp Stomatol, Dept Prosthodont, Wenzhou 325027, Peoples R China; 2.First Affiliated Hosp, Wenzhou Med Coll, Dept Gen Med, Wenzhou 325000, Peoples R China |
第一作者单位 | 口腔医学院、附属口腔医院 |
第一作者的第一单位 | 口腔医学院、附属口腔医院 |
推荐引用方式 GB/T 7714 | Liu, Jinsong,Xu, Lihua,Deng, Zhennan,et al. Traditional Chinese Medicine Epimedium Release from PLGA/HA Scaffolds Prepared in Supercritical CO2[C]. DURNTEN-ZURICH:TRANS TECH PUBLICATIONS LTD,2012:48-+. |
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