科研成果详情

题名Traditional Chinese Medicine Epimedium Release from PLGA/HA Scaffolds Prepared in Supercritical CO2
作者
发表日期2012-12-31
会议录名称ADVANCED RESEARCH ON ENGINEERING MATERIALS, ENERGY, MANAGEMENT AND CONTROL, PTS 1 AND 2   影响因子和分区
语种英语
原始文献类型Proceedings Paper
关键词Tissue engineering drug release scaffold epimedium
其他关键词FABRICATION
摘要Traditional chinese medicine epimedium was introduced into the poly(D,L-lactide-co-glycolide) / hydroxyapatite (PLGA/HA) scaffolds by using a supercritical CO2 technique. The morphology, porosity, mechanical strength, degradation behaviors, and drug release kenitics of scaffolds with 1 wt%, 5 wt% and 10 wt% of epimedium were determined. The results revealed that the micropores and macropores in the scaffolds were interconnect, and the addition of drug had little effect on the morphology of scaffolds. When the drug was at 10 wt%, the porosity and mechnical strength of scaffolds were deteriorated. The dosage of epimedium in scaffolds exhibits an signficant influence on weight loss of scaffolds and release kenitics of epimedium. Within the limits of our study, 5 wt% epimedium loaded scaffolds might be suitable for bone tissue egineering application.
资助项目Science and technology bureau of Wenzhou City [2011S0088]; Natural Science Foundation of Zhejiang ProvinceNatural Science Foundation of Zhejiang Province [Y2110401, Y12H140011]
出版者TRANS TECH PUBLICATIONS LTD
出版地DURNTEN-ZURICH
ISSN1022-6680
卷号424-425
页码48-+
DOI10.4028/www.scientific.net/AMR.424-425.48
页数2
WOS类目Engineering, Mechanical ; Materials Science, Multidisciplinary
WOS研究方向Engineering ; Materials Science
WOS记录号WOS:000302663400012
收录类别CPCI ; EI
EI入藏号20120414713968
EI主题词Scaffolds (biology)
会议名称2nd International Conference on Engineering Materials, Energy, Management and Control
会议地点Wuhan, PEOPLES R CHINA
会议日期MAR 17-18, 2012
引用统计
被引频次[WOS]:0   [WOS记录]     [WOS相关记录]
文献类型会议论文
条目标识符https://kms.wmu.edu.cn/handle/3ETUA0LF/22009
专题口腔医学院、附属口腔医院
附属第一医院_全科医学科
通讯作者Liu, Jinsong
作者单位
1.Wenzhou Med Coll, Sch & Hosp Stomatol, Dept Prosthodont, Wenzhou 325027, Peoples R China;
2.First Affiliated Hosp, Wenzhou Med Coll, Dept Gen Med, Wenzhou 325000, Peoples R China
第一作者单位口腔医学院、附属口腔医院
第一作者的第一单位口腔医学院、附属口腔医院
推荐引用方式
GB/T 7714
Liu, Jinsong,Xu, Lihua,Deng, Zhennan,et al. Traditional Chinese Medicine Epimedium Release from PLGA/HA Scaffolds Prepared in Supercritical CO2[C]. DURNTEN-ZURICH:TRANS TECH PUBLICATIONS LTD,2012:48-+.

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