Sleeve lobectomy versus pneumonectomy following neoadjuvant therapy in patients with non-small cell lung cancer

doi:10.1093/ejcts/ezae300

科研成果详情

题名	Sleeve lobectomy versus pneumonectomy following neoadjuvant therapy in patients with non-small cell lung cancer
作者	Teng, Meixin 1,2; Yi, Chengxiang 1; Yang, Weiguang 1; Zhang, Jing 1; Yao, Wangchao 1; Hu, Shiqi 3; Qing, Yang 2; Ji, Shuyu 1; Shen, Ziyun 1,4; Zhang, Peng 1,2
发表日期	2024-08-21
发表期刊	EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Non-small cell lung cancer Neoadjuvant therapy Sleeve lobectomy Pneumonectomy Postoperative complications
其他关键词	SURGERY
摘要	OBJECTIVES: Neoadjuvant therapy has gained widespread acceptance as the standard modality for locally advanced non-small cell lung cancer. However, the clinical benefit of sleeve lobectomy (SL) or pneumonectomy (PN) following neoadjuvant therapy remains controversial. METHODS: The clinical and pathological characteristics of non-small cell lung cancer patients who underwent SL or PN after neoadjuvant therapy at a high-volume single centre between December 2019 and March 2023 were retrospectively collected. The SL group was matched 4:1 with the PN group by propensity score matching. The surgical outcomes were systematically collected and analysed. RESULTS: During a 5-year study period, the majority of patients (175 of 215, 81.4%) underwent the SL procedure, while 40 patients (18.6%) underwent PN. Following propensity score matching, the SL group exhibited lower postoperative arrythmia (4.8% vs 26.9%, P < 0.001), lower 30-day mortality (1.0% vs 7.7%, P = 0.046) and a shorter length of postoperative hospital stay (6.0 days vs 10.0 days, P < 0.001), compared with the PN group. In addition, no significant difference was observed between the two groups in terms of disease-free survival or overall survival (P = 0.977 and P = 0.913, respectively). CONCLUSIONS: SL stands as a safe and feasible option for patients with centrally located non-small-cell lung cancer who have undergone neoadjuvant therapy, in comparison to PN. This finding suggests that SL remains the preferable choice when feasible in the context of the widespread utilization of neoadjuvant therapy.
资助项目	Science and Technology Commission of Shanghai Municipality [23YF1435200]; Innovation Program of Shanghai Municipal Education Commission [2023ZKZD33]; Foundation of Shanghai Pulmonary Hospital [FKLY20004, FKCX2304]; Beijing CSCO Clinical Oncology Research Foundation [Y-BMS2019-089]
出版者	OXFORD UNIV PRESS INC
ISSN	1010-7940
EISSN	1873-734X
卷号	66 期号:2
DOI	10.1093/ejcts/ezae300
页数	8
WOS类目	Cardiac & Cardiovascular Systems ; Respiratory System ; Surgery
WOS研究方向	Cardiovascular System & Cardiology ; Respiratory System ; Surgery
WOS记录号	WOS:001295349800001
收录类别	SCIE ; SCOPUS ; PUBMED
URL	查看原文
PubMed ID	39120883
SCOPUSEID	2-s2.0-85202059461
通讯作者地址	[Shen, Ziyun;Zhang, Peng]Tongji Univ, Shanghai Pulm Hosp, Sch Med, Dept Thorac Surg, 507 Zhengmin Rd, Shanghai 200433, Peoples R China.
Scopus学科分类	Surgery;Pulmonary and Respiratory Medicine;Cardiology and Cardiovascular Medicine
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/217369
专题	附属第一医院附属第一医院_心胸外科
通讯作者	Shen, Ziyun; Zhang, Peng
作者单位	1.Tongji Univ, Shanghai Pulm Hosp, Sch Med, Dept Thorac Surg, 507 Zhengmin Rd, Shanghai 200433, Peoples R China; 2.Shihezi Univ, Sch Med, Dept Thorac Surg, Shihezi, Xinjiang, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 1, Dept Thorac Surg, Wenzhou, Zhejiang, Peoples R China; 4.Tongji Univ, Shanghai Pulm Hosp, Sch Med, Cent Lab, Shanghai, Peoples R China
推荐引用方式 GB/T 7714	Teng, Meixin,Yi, Chengxiang,Yang, Weiguang,et al. Sleeve lobectomy versus pneumonectomy following neoadjuvant therapy in patients with non-small cell lung cancer[J]. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY,2024,66(2).
APA	Teng, Meixin., Yi, Chengxiang., Yang, Weiguang., Zhang, Jing., Yao, Wangchao., ... & Zhang, Peng. (2024). Sleeve lobectomy versus pneumonectomy following neoadjuvant therapy in patients with non-small cell lung cancer. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 66(2).
MLA	Teng, Meixin,et al."Sleeve lobectomy versus pneumonectomy following neoadjuvant therapy in patients with non-small cell lung cancer".EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY 66.2(2024).