Comparison of survival between palliative surgery and no surgery for advanced tongue squamous cell carcinoma: an analysis of SEER data

doi:10.1016/j.ijom.2024.07.001

科研成果详情

题名	Comparison of survival between palliative surgery and no surgery for advanced tongue squamous cell carcinoma: an analysis of SEER data
作者	Ye Z.1; Tan G.2; Wang L.3; Shangguan G.1; Yao H.4; Xu X.4; Ye H.5; Ding X.4
发表日期	2024
发表期刊	International Journal of Oral and Maxillofacial Surgery; 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Palliative surgery SEER program Squamous cell carcinoma Survival analysis Therapy Tongue
摘要	The aim of this study was to investigate the survival effect of palliative surgery in advanced tongue squamous cell carcinoma (TSCC). A retrospective analysis of data in the SEER database for 6151 patients with stage III/IV TSCC (American Joint Committee on Cancer (AJCC) staging), diagnosed between 2004 and 2015, was performed. The patients were divided into two groups: palliative surgery and no surgery. Kaplan–Meier and Cox proportional hazards regression analyses were applied to determine risk factors for overall survival (OS) and cancer-specific survival (CSS). A further analysis was performed using 1:1 propensity score matching (PSM) to balance 13 patient variables (sex, age at diagnosis, race, marital status, primary tumour site, SEER stage, AJCC stage, pathological differentiation grade, tumour size, lymph node metastasis, previous lymph node removal, radiotherapy, and chemotherapy). Among the 6151 patients, 706 underwent palliative surgery; the other 5445 did not undergo any kind of surgery. Those who underwent palliative surgery had a higher 5-year survival rate. After PSM, 1274 patients were included in the matched cohort. Multivariate Cox regression analysis showed that patients who underwent palliative surgery had a lower risk of death than those who did not (OS: hazard ratio 0.58, 95% confidence interval 0.49–0.69, P < 0.001; CSS: hazard ratio 0.60, 95% confidence interval 0.49–0.74, P < 0.001). In this comparative study it was found that compared with no surgery, palliative surgery has a positive impact on the survival rate of patients with advanced TSCC.
资助项目	Wenzhou Municipal Science and Technology Bureau Projects, China[Y20220378];Wenzhou Major Scientific and Technological Innovation Project[ZY2022022];
ISSN	0901-5027
EISSN	1399-0020
DOI	10.1016/j.ijom.2024.07.001
收录类别	SCOPUS ; PUBMED
URL	查看原文
PubMed ID	39025738
SCOPUSEID	2-s2.0-85199202667
通讯作者地址	[Ding X.]Department of Maxillofacial Surgery,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325015,China
Scopus学科分类	Surgery;Oral Surgery;Otorhinolaryngology
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/217010
专题	附属第一医院数字化医学与智能技术研究院
通讯作者	Ding X.
作者单位	1.Department of Maxillofacial Surgery,The People's Hospital of Pingyang (Pingyang Hospital of Wenzhou Medical University),Zhejiang,Wenzhou,China; 2.Advanced Neuroimaging Laboratory,Department of Radiology,The Affiliated Yuebei People's Hospital of Shantou University Medical College,Guangdong,Shaoguan,China; 3.School and Hospital of Stomatology,Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine and Optional Institutions,Guangzhou Medical University,Guangdong,Guangzhou,China; 4.Department of Maxillofacial Surgery,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China; 5.Institute of Digitized Medicine and Intelligent Technology,Wenzhou Medical University,Zhejiang,Wenzhou,China
第一作者单位	温州医科大学
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Ye Z.,Tan G.,Wang L.,et al. Comparison of survival between palliative surgery and no surgery for advanced tongue squamous cell carcinoma: an analysis of SEER data[J]. International Journal of Oral and Maxillofacial Surgery;,2024.
APA	Ye Z.., Tan G.., Wang L.., Shangguan G.., Yao H.., ... & Ding X.. (2024). Comparison of survival between palliative surgery and no surgery for advanced tongue squamous cell carcinoma: an analysis of SEER data. International Journal of Oral and Maxillofacial Surgery;.
MLA	Ye Z.,et al."Comparison of survival between palliative surgery and no surgery for advanced tongue squamous cell carcinoma: an analysis of SEER data".International Journal of Oral and Maxillofacial Surgery; (2024).