Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasia An animal experimental study

doi:10.1080/02656736.2024.2328113

科研成果详情

题名	Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasia An animal experimental study
作者	Xu, Qi 1; Xu, Xiao-hui 2; Liu, Ze-zheng 1; Zhu, Jian-bi 1; Ding, Huan-huan1; Jin, Chun-chun 1; Yan, Zhi-han3,4
发表日期	2024-12-31
发表期刊	INTERNATIONAL JOURNAL OF HYPERTHERMIA 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Percutaneous radiofrequency ablation synovial hyperplasia animal experiment research ultrasonography arthritis treatment
其他关键词	RHEUMATOID-ARTHRITIS ; METHOTREXATE ; MANAGEMENT ; CARCINOMA ; DRUG
摘要	Purpose: This study aimed to investigate the efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation (RFA) for the treatment of synovial hyperplasia in the knee joints of antigen-induced arthritis (AIA) model rabbits. Methods: Forty Japanese large-eared white rabbits were divided into AIA and control groups. After successful induction of the AIA model, the knee joints were randomly assigned to RFA and non-RFA groups. The RFA group underwent ultrasound-guided RFA to treat synovial hyperplasia in the knee joint. Dynamic observation of various detection indices was conducted to evaluate the safety and effectiveness of the RFA procedure. Results: Successful synovial ablation was achieved in the RFA group, with no intraoperative or perioperative mortality. Postoperative the circumference of the knee joint reached a peak before decreasing in the third week after surgery. The incidence and diameter of postoperative skin ulcers were not significantly different compared to the non-RFA group (p > .05). Anatomical examination revealed an intact intermuscular fascia around the ablated area in the RFA group. The ablated synovial tissue initially presented as a white mass, which subsequently liquefied into a milky white viscous fluid. Gross articular cartilage was observed, along with liquefied necrosis of the synovium on pathological histology and infiltration of inflammatory cells in the surrounding soft tissue. Conclusion: The experimental results demonstrated that ultrasound-guided RFA of the knee in the treatment of synovial hyperplasia in AIA model animals was both effective and safe.
资助项目	Wenzhou Science and Technology Project
出版者	TAYLOR & FRANCIS LTD
ISSN	0265-6736
EISSN	1464-5157
卷号	41 期号:1
DOI	10.1080/02656736.2024.2328113
页数	12
WOS类目	Oncology ; Radiology, Nuclear Medicine & Medical Imaging
WOS研究方向	Oncology ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:001263033600001
收录类别	SCIE ; SCOPUS
URL	查看原文
PubMed ID	3896475
SCOPUSEID	2-s2.0-85197525081
通讯作者地址	[Yan, Zhi-han]Wenzhou Med Univ, Affiliated Hosp 2, Dept Radiol, Wenzhou Key Lab Struct & Funct Imaging, 109 Xueyuan West Rd, Wenzhou 325000, Zhejiang, Peoples R China. ; [Yan, Zhi-han]Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou Key Lab Struct & Funct Imaging, 109 Xueyuan West Rd, Wenzhou 325000, Zhejiang, Peoples R China.
Scopus学科分类	Physiology;Physiology (medical);Cancer Research
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/216777
专题	其他_附属第三医院（瑞安市人民医院）第二临床医学院，附属第二医院、育英儿童医院附属第二医院_放射科第一临床医学院（信息与工程学院）、附属第一医院_医疗保健中心
通讯作者	Yan, Zhi-han
作者单位	1.Shanghai Univ, Wenzhou Med Univ, Affiliated Hosp 3, Wenzhou Peoples Hosp,Dept Ultrasound, Wenzhou, Peoples R China; 2.Wenzhou Med Univ, Affiliated Hosp 1, Dept Med & Hlth Care Ctr, Wenzhou, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 2, Dept Radiol, Wenzhou Key Lab Struct & Funct Imaging, 109 Xueyuan West Rd, Wenzhou 325000, Zhejiang, Peoples R China; 4.Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou Key Lab Struct & Funct Imaging, 109 Xueyuan West Rd, Wenzhou 325000, Zhejiang, Peoples R China
第一作者单位	其他_附属第三医院（瑞安市人民医院）
通讯作者单位	附属第二医院_放射科; 第二临床医学院，附属第二医院、育英儿童医院
第一作者的第一单位	其他_附属第三医院（瑞安市人民医院）
推荐引用方式 GB/T 7714	Xu, Qi,Xu, Xiao-hui,Liu, Ze-zheng,et al. Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasia An animal experimental study[J]. INTERNATIONAL JOURNAL OF HYPERTHERMIA,2024,41(1).
APA	Xu, Qi., Xu, Xiao-hui., Liu, Ze-zheng., Zhu, Jian-bi., Ding, Huan-huan., ... & Yan, Zhi-han. (2024). Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasia An animal experimental study. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 41(1).
MLA	Xu, Qi,et al."Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasia An animal experimental study".INTERNATIONAL JOURNAL OF HYPERTHERMIA 41.1(2024).