Effect of Preoperative Nutritional Status on Clinical Outcome After Surgery for Early-Stage Non-Small Cell Lung Cancer

科研成果详情

题名	Effect of Preoperative Nutritional Status on Clinical Outcome After Surgery for Early-Stage Non-Small Cell Lung Cancer
作者	Lu, Kaiming 1; Pan, Xiongfeng 2; Zheng, Jinyu3; Cheng, Dezhi3; Zheng, Liangcheng3; Zhang, Xinbo 3
发表日期	2024-05
发表期刊	CURRENT TOPICS IN NUTRACEUTICAL RESEARCH 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Non -small cell lung cancer Nutritional Status Surgical Outcomes Preoperative Care
摘要	This study aimed to determine whether preoperative nutritional status affects surgical outcomes in patients with earlystage non-small cell lung cancer. This cross-sectional study included 80 patients scheduled for non-small cell lung cancer surgery. Patients with protein-energy malnutrition were identified using recent weight loss, serum albumin levels, and total lymphocyte count. Recovery time, complication rates, and overall survival were evaluated as surgical outcomes using logistic regression, Cox proportional hazards models, and Kaplan-Meier survival analysis. We found that preoperative nutritional status was a substantial predictor of surgical outcomes. Well-nourished patients had 2.5 times lower surgical success rates and considerably lower incidences of adverse events than those who were severely malnourished. Additionally, malnutrition was correlated with prolonged hospital stays and recovery periods. Kaplan-Meier analysis of survival shows that well-nourished patients had a considerably longer survival period. The independent predictive power of nutritional status over postoperative outcomes was validated using multivariate analysis, highlighting the importance of implementing focused nutritional interventions. We demonstrated the importance of preoperative nutritional evaluations and interventions in enhancing survival, reducing complications, and improving surgical success rates among patients with non-small cell lung cancer. Incorporating nutritional support into preoperative care protocols substantially affected the clinical outcomes of patients undergoing non-small cell lung cancer surgery.
资助项目	Basic scientific research project of Wenzhou Science and Technology Bureau [Y2023899]
出版者	NEW CENTURY HEALTH PUBLISHERS, LLC
ISSN	1540-7535
EISSN	2641-452X
卷号	22 期号:2 页码:649-656
页数	8
WOS类目	Nutrition & Dietetics ; Pharmacology & Pharmacy
WOS研究方向	Nutrition & Dietetics ; Pharmacology & Pharmacy
WOS记录号	WOS:001237048800043
收录类别	SCIE
通讯作者地址	[Zhang, Xinbo]Wenzhou Med Univ, Affiliated Hosp 1, Dept Thorac Surg, Wenzhou 325000, Peoples R China.
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/214696
专题	附属第一医院其他_附属苍南医院（苍南县人民医院）
通讯作者	Zhang, Xinbo
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 1, Dept Operating Room, Wenzhou 325000, Peoples R China; 2.Wenzhou Med Univ, Affiliated Cangnan Hosp, Dept Thorac Surg, Wenzhou 325800, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 1, Dept Thorac Surg, Wenzhou 325000, Peoples R China
第一作者单位	附属第一医院; 手术室
通讯作者单位	附属第一医院; 心胸外科
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Lu, Kaiming,Pan, Xiongfeng,Zheng, Jinyu,et al. Effect of Preoperative Nutritional Status on Clinical Outcome After Surgery for Early-Stage Non-Small Cell Lung Cancer[J]. CURRENT TOPICS IN NUTRACEUTICAL RESEARCH,2024,22(2):649-656.
APA	Lu, Kaiming, Pan, Xiongfeng, Zheng, Jinyu, Cheng, Dezhi, Zheng, Liangcheng, & Zhang, Xinbo. (2024). Effect of Preoperative Nutritional Status on Clinical Outcome After Surgery for Early-Stage Non-Small Cell Lung Cancer. CURRENT TOPICS IN NUTRACEUTICAL RESEARCH, 22(2), 649-656.
MLA	Lu, Kaiming,et al."Effect of Preoperative Nutritional Status on Clinical Outcome After Surgery for Early-Stage Non-Small Cell Lung Cancer".CURRENT TOPICS IN NUTRACEUTICAL RESEARCH 22.2(2024):649-656.