Expression of chemokine receptor CCR3 in breast cancer and its clinicopathological significance

科研成果详情

题名	Expression of chemokine receptor CCR3 in breast cancer and its clinicopathological significance
作者	Gong, Di-He 1; Hu, Jie 2; Xiong, Guan-Jun 2
发表日期	2014-08-10
发表期刊	Journal of Practical Oncology 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Breast neoplasms/pathology Immunohisto-chemistry Lymphatic metastasis Receptors, chemokine/metabolism
摘要	Objective: To investigate the expression of chemokine receptor CCR3 in breast cancer and its clinicopathological significance. Methods: The expression of CCR3 was evaluated by immunohistochemistry in breast cancer tissues from 150 cases and the corresponding normal breast tissues. The association of CCR3 expression with clinicopathological features was analyzed. Results: The positive expression rate of CCR3 in breast cancer tissues was significantly higher than that in normal breast tissues (86.7% vs 14.0%, P<0.001). The expression of CCR3 was not correlated with age, cTNM stage, tumor size, axillary lymph node metastasis, estrogen receptor, progesterone receptor and HER-2 status (P>0.05). Conclusion: Chemokine receptor CCR3 is highly expressed in breast cancer, however, it may be not correlated with clinicopathological features of the disease.
出版者	Journal of Practical Oncology, Editorial Board
ISSN	1001-1692
卷号	29 期号:4 页码:360-363
收录类别	SCOPUS
URL	查看原文
SCOPUSEID	2-s2.0-84906822231
Scopus学科分类	Oncology;Cancer Research
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/214456
专题	其他_附属慈溪医院（慈溪市人民医院）
作者单位	1.Department of General Surgery,The Cixi Hospital Affiliated to Wenzhou Medical University,Cixi,315300,China; 2.Department of Pathology,The Cixi Hospital Affiliated to Wenzhou Medical University,Cixi,315300,China
第一作者单位	其他_附属慈溪医院（慈溪市人民医院）
第一作者的第一单位	其他_附属慈溪医院（慈溪市人民医院）
推荐引用方式 GB/T 7714	Gong, Di-He,Hu, Jie,Xiong, Guan-Jun. Expression of chemokine receptor CCR3 in breast cancer and its clinicopathological significance[J]. Journal of Practical Oncology,2014,29(4):360-363.
APA	Gong, Di-He, Hu, Jie, & Xiong, Guan-Jun. (2014). Expression of chemokine receptor CCR3 in breast cancer and its clinicopathological significance. Journal of Practical Oncology, 29(4), 360-363.
MLA	Gong, Di-He,et al."Expression of chemokine receptor CCR3 in breast cancer and its clinicopathological significance".Journal of Practical Oncology 29.4(2014):360-363.