Peptide and peptide-based drugs

doi:10.1016/B978-0-443-18611-0.00015-2

科研成果详情

题名	Peptide and peptide-based drugs
作者	Wang, Lei 1; Wang, Nanxi 2; Yan, Zhibin 1; Huang, Zhifeng3; Fu, Caiyun 1
来源专著	Privileged Scaffolds in Drug Discovery
语种	英语
原始文献类型	Book Chapter
关键词	Amino acid Hormone Nonnatural amino acid Peptide Target
摘要	Peptide drugs are a unique class of pharmaceutical agents involved in a wide range of therapeutic areas, including urology, respiratory, pain, oncology, metabolic, cardiovascular, and antimicrobial applications. More than 80 peptide drugs have been approved and marketed worldwide. A lot of them mimicked their initial natural sources, such as natural hormones and natural bioactive peptides from bacteria, fungi, plants, and animal, or had the same structure. Since 2000, peptide drug development has entered a new era as a result of technological advances in structural biology, recombinant biologics, and synthetic and analytic technologies. Peptide drugs are no longer simply hormone mimics or composed simply of natural amino acids. This chapter summarizes and discusses the structures, modifications, and biological functions of peptide drugs approved since 2000.
出版者	Elsevier
ISBN	[{$=9780443186110}, {$=9780443186127}]
页码	795-815
DOI	10.1016/B978-0-443-18611-0.00015-2
收录类别	SCOPUS
出版日期	2023
URL	查看原文
Scopus记录号	2-s2.0-85176837929
Scopus学科分类	Medicine (all);Pharmacology, Toxicology and Pharmaceutics (all)
引用统计
文献类型	专著章节
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/214437
专题	药学院（分析测试中心）
作者单位	1.Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine,College of Life Sciences and Medicine,Zhejiang Sci-Tech University,Zhejiang,Hangzhou,China; 2.State Key Laboratory Cultivation Base for TCM Quality and Efficacy,Nanjing University of Chinese Medicine,Jiangsu,Nanjing,China; 3.School of Pharmaceutical Sciences,Wenzhou Medical University,Zhejiang,Wenzhou,China
推荐引用方式 GB/T 7714	Wang, Lei,Wang, Nanxi,Yan, Zhibin,et al. Peptide and peptide-based drugs:Elsevier,2023:795-815.