Sphingosine 1-Phosphate Metabolism and Signaling

doi:10.1007/978-981-19-0394-6_6

科研成果详情

题名	Sphingosine 1-Phosphate Metabolism and Signaling
作者	Hu, Yan; Dai, Kezhi
来源专著	Advances in Experimental Medicine and Biology
语种	英语
原始文献类型	Book Chapter
关键词	Receptor signaling Sphingolipid metabolism Sphingosine 1-phosphate
摘要	Sphingosine 1-phosphate (S1P) is a well-defined bioactive lipid molecule derived from membrane sphingolipid metabolism. In the past decades, a series of key enzymes involved in generation of S1P have been identified and characterized in detail, as well as enzymes degrading S1P. S1P requires transporter to cross the plasma membrane and carrier to deliver to its cognate receptors and therefore transduces signaling in autocrine, paracrine, or endocrine fashions. The essential roles in regulation of development, metabolism, inflammation, and many other aspects of life are mainly executed when S1P binds to receptors provoking the downstream signaling cascades in distinct cells. This chapter will review the synthesis, degradation, transportation, and signaling of S1P and try to provide a comprehensive view of the biology of S1P, evoking new enthusiasms and ideas into the field of the fascinating S1P.
资助项目	Natural Science Foundation of Zhejiang Province[LY20C070002]
出版者	Springer
卷号	1372
ISSN	0065-2598
EISSN	2214-8019
页码	67-76
DOI	10.1007/978-981-19-0394-6_6
收录类别	SCOPUS
出版日期	2022
URL	查看原文
Pubmed记录号	35503175
Scopus记录号	2-s2.0-85129634045
Scopus学科分类	Biochemistry, Genetics and Molecular Biology (all)
通讯作者地址	[Dai, Kezhi]Department of Psychiatry,School of Mental Health,Wenzhou Medical University,Zhejiang,Wenzhou,China
引用统计
文献类型	专著章节
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/214418
专题	第一临床医学院（信息与工程学院）、附属第一医院_精神病与精神卫生学
通讯作者	Dai, Kezhi
作者单位	Department of Psychiatry,School of Mental Health,Wenzhou Medical University,Wenzhou,China
第一作者单位	第一临床医学院（信息与工程学院）、附属第一医院_精神病与精神卫生学
通讯作者单位	第一临床医学院（信息与工程学院）、附属第一医院_精神病与精神卫生学
第一作者的第一单位	第一临床医学院（信息与工程学院）、附属第一医院_精神病与精神卫生学
推荐引用方式 GB/T 7714	Hu, Yan,Dai, Kezhi. Sphingosine 1-Phosphate Metabolism and Signaling:Springer,2022:67-76.