Should we should consider day 3 blastomere number during single vitrified-warmed blastocyst transfer cycle? A retrospective study

doi:10.1016/j.ejogrb.2024.04.021

科研成果详情

题名	Should we should consider day 3 blastomere number during single vitrified-warmed blastocyst transfer cycle? A retrospective study
作者	Zhou, Haisu1; Ye, Lianmin2; Zhang, Huan1; Zheng, Yi 1; Jin, Wumin1
发表日期	2024-06-01
发表期刊	European Journal of Obstetrics and Gynecology and Reproductive Biology; 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Blastocyst Clinical pregnancy Embryo Live birth Vitrification
其他关键词	PREGNANCY OUTCOMES ; EMBRYO MORPHOLOGY ; CELL NUMBER ; FRESH
摘要	The present study investigated whether day 3 blastomere number has an effect on the clinical outcomes during single vitrified-warmed blastocyst transfer cycles. A total of 3294 vitrified-warmed single day 5 blastocyst transferred cycles were analyzed in this retrospective study from January 2018 to December 2021. The cycles were divided into ≥ 7 and < 7 blastomere groups depending on the day 3 embryo blastomere number. The clinical outcomes were compared between the two groups, moreover multivariate logistic regression analysis was conducted to investigate the correlation between the number of day 3 blastomeres and clinical outcomes. The chi-square test demonstrated that the rates of clinical pregnancy and live birth were significantly higher in the ≥ 7 blastomere group compared to the < 7 blastomere group with respect to single high-quality blastocyst transfer cycles. Conversely, these rates were similar in the two groups with respect to single low-quality blastocyst transfer cycles. These results were confirmed by multivariate logistic regression analysis. However, the miscarriage rate was higher in the < 7 blastomere group than in ≥ 7 group during low-quality blastocyst transfer cycles. These results suggested that day 3 blastomere number should be considered during single vitrified-warmed blastocyst transfer cycles. Thus, blastocsyts derived from ≥ 7 blastomere embryos are preferred when choosing the same quality blastocysts.
资助项目	Wenzhou Key Laboratory of Reproduction and Genetics [22HZSY0051]
出版者	Elsevier Ireland Ltd
ISSN	0301-2115
EISSN	1872-7654
卷号	297 页码:209-213
DOI	10.1016/j.ejogrb.2024.04.021
页数	5
WOS类目	Obstetrics & Gynecology ; Reproductive Biology
WOS研究方向	Obstetrics & Gynecology ; Reproductive Biology
WOS记录号	WOS:001289826400001
收录类别	SCOPUS ; PUBMED ; SCIE
URL	查看原文
PubMed ID	38688135
SCOPUSEID	2-s2.0-85191336441
通讯作者地址	[Jin, Wumin]null
Scopus学科分类	Reproductive Medicine;Obstetrics and Gynecology
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/212665
专题	附属第一医院_生殖医学中心附属第一医院
通讯作者	Jin, Wumin
作者单位	1.Reproductive Medicine Center,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 2.Department of Intensive Care Unit,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China
第一作者单位	附属第一医院_生殖医学中心
第一作者的第一单位	附属第一医院_生殖医学中心
推荐引用方式 GB/T 7714	Zhou, Haisu,Ye, Lianmin,Zhang, Huan,et al. Should we should consider day 3 blastomere number during single vitrified-warmed blastocyst transfer cycle? A retrospective study[J]. European Journal of Obstetrics and Gynecology and Reproductive Biology;,2024,297:209-213.
APA	Zhou, Haisu, Ye, Lianmin, Zhang, Huan, Zheng, Yi, & Jin, Wumin. (2024). Should we should consider day 3 blastomere number during single vitrified-warmed blastocyst transfer cycle? A retrospective study. European Journal of Obstetrics and Gynecology and Reproductive Biology;, 297, 209-213.
MLA	Zhou, Haisu,et al."Should we should consider day 3 blastomere number during single vitrified-warmed blastocyst transfer cycle? A retrospective study".European Journal of Obstetrics and Gynecology and Reproductive Biology; 297(2024):209-213.