Impact of scandium and terbium on the mechanical properties, corrosion behavior, and biocompatibility of biodegradable Mg-Zn-Zr-Mn alloys

doi:10.1016/j.jma.2024.02.002

科研成果详情

题名	Impact of scandium and terbium on the mechanical properties, corrosion behavior, and biocompatibility of biodegradable Mg-Zn-Zr-Mn alloys
作者	Munir, Khurram 1; Lin, Jixing2; Tong, Xian2; Biesiekierski, Arne 1; Li, Yuncang 1; Wen, Cuie 1
发表日期	2024-02
发表期刊	Journal of Magnesium and Alloys 影响因子和分区
语种	英语
原始文献类型	Journal article (JA)
关键词	Biocompatibility Biomechanics Bone Calcium alloys Compressive strength Corrosion rate Corrosion resistance Corrosion resistant alloys Corrosive effects Gadolinium alloys Magnesium castings Manganese alloys Rare earth elements Rare earths Zinc alloys Zircaloy Biodegradable magnesiums Bone implant Corrosion behaviour Corrosion property Human bodies In vitro cytotoxicity In-vitro Mechanical biocompatibility Physiological environment Vitro cytotoxicities
其他关键词	RARE-EARTH-ELEMENTS ; HIGH-PURITY MG ; MAGNESIUM ALLOYS ; IN-VITRO ; TISSUE DISTRIBUTION ; DEGRADATION BEHAVIOR ; PURE MG ; MICROSTRUCTURE ; EXTRUSION ; AZ91
摘要	Magnesium (Mg)-based bone implants degrade rapidly in the physiological environment of the human body which affects their structural integrity and biocompatibility before adequate bone repair. Rare earth elements (REEs) have demonstrated their effectiveness in tailoring the corrosion and mechanical behavior of Mg alloys. This study methodically investigated the impacts of scandium (Sc) and terbium (Tb) in tailoring the corrosion resistance, mechanical properties, and biocompatibility of Mg–0.5Zn–0.35Zr–0.15Mn (MZZM) alloys fabricated via casting and hot extrusion. Results indicate that addition of Sc and Tb improved the strength of MZZM alloys via grain size reduction and solid solution strengthening mechanisms. The extruded MZZM–(1–2)Sc–(1–2)Tb (wt.%) alloys exhibit compressive strengths within the range of 336–405 MPa, surpassing the minimum required strength of 200 MPa for bone implants by a significant margin. Potentiodynamic polarization tests revealed low corrosion rates of as–cast MZZM (0.25 mm/y), MZZM–2Tb (0.45 mm/y), MZZM–1Sc–1Tb (0.18 mm/y), and MZZM–1Sc–2Tb (0.64 mm/y), and extruded MZZM (0.17 mm/y), MZZM–1Sc (0.15 mm/y), MZZM-2Sc (0.45 mm/y), MZZM-1Tb (0.17 mm/y), MZZM-2Tb (0.10 mm/y), MZZM–1Sc-1Tb (0.14 mm/y), MZZM-1Sc-2Tb (0.40 mm/y), and MZZM–2Sc–2Tb (0.51 mm/y) alloys, which were found lower compared to corrosion rate of high-purity Mg (∼1.0 mm/y) reported in the literature. Furthermore, addition of Sc, or Tb, or Sc and Tb to MZZM alloys did not adversely affect the viability of SaOS2 cells, but enhanced their initial cell attachment, proliferation, and spreading shown via polygonal shapes and filipodia. This study emphasizes the benefits of incorporating Sc and Tb elements in MZZM alloys, as they effectively enhance corrosion resistance, mechanical properties, and biocompatibility simultaneously. © 2024
资助项目	Australian Research Council[DP170102557,FT160100252];
出版者	KeAi Communications Co.
ISSN	2213-9567
卷号	12 期号:2 页码:546-572
DOI	10.1016/j.jma.2024.02.002
页数	27
WOS类目	Metallurgy & Metallurgical Engineering
WOS研究方向	Metallurgy & Metallurgical Engineering
WOS记录号	WOS:001189012300001
收录类别	EI ; SCOPUS ; SCIE
EI入藏号	20241015681509
EI主题词	Magnesium alloys
EI分类号	461.2 Biological Materials and Tissue Engineering ; 461.3 Biomechanics, Bionics and Biomimetics ; 461.9.1 Immunology ; 531 Metallurgy and Metallography ; 534.2 Foundry Practice ; 539.1 Metals Corrosion ; 542.2 Magnesium and Alloys ; 543.2 Manganese and Alloys ; 546.3 Zinc and Alloys ; 547.2 Rare Earth Metals ; 549.2 Alkaline Earth Metals ; 804.2 Inorganic Compounds
URL	查看原文
SCOPUSEID	2-s2.0-85186312760
通讯作者地址	[Li, Yuncang]School of Engineering,RMIT University,Melbourne,3001,Australia
Scopus学科分类	Mechanics of Materials;Metals and Alloys
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/210416
专题	口腔医学院、附属口腔医院
通讯作者	Li, Yuncang
作者单位	1.School of Engineering,RMIT University,Melbourne,3001,Australia; 2.School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,325027,China
推荐引用方式 GB/T 7714	Munir, Khurram,Lin, Jixing,Tong, Xian,et al. Impact of scandium and terbium on the mechanical properties, corrosion behavior, and biocompatibility of biodegradable Mg-Zn-Zr-Mn alloys[J]. Journal of Magnesium and Alloys,2024,12(2):546-572.
APA	Munir, Khurram, Lin, Jixing, Tong, Xian, Biesiekierski, Arne, Li, Yuncang, & Wen, Cuie. (2024). Impact of scandium and terbium on the mechanical properties, corrosion behavior, and biocompatibility of biodegradable Mg-Zn-Zr-Mn alloys. Journal of Magnesium and Alloys, 12(2), 546-572.
MLA	Munir, Khurram,et al."Impact of scandium and terbium on the mechanical properties, corrosion behavior, and biocompatibility of biodegradable Mg-Zn-Zr-Mn alloys".Journal of Magnesium and Alloys 12.2(2024):546-572.