Advances in Bio-Optical Imaging Systems for Spatiotemporal Monitoring of Intestinal Bacteria

doi:10.1002/mnfr.202300760

科研成果详情

题名	Advances in Bio-Optical Imaging Systems for Spatiotemporal Monitoring of Intestinal Bacteria
作者	Pan, Tongtong 1; Su, Lihuang 2; Zhang, Yiying 3; Xu, Liang4; Chen, Yongping1
发表日期	2024-04
发表期刊	MOLECULAR NUTRITION & FOOD RESEARCH 影响因子和分区
语种	英语
原始文献类型	Review ; Early Access
关键词	antibiotic-based staining intestinal microbiome metabolic labeling optical nanomaterial photoacoustic
其他关键词	GREEN FLUORESCENT PROTEIN ; STAPHYLOCOCCUS-AUREUS ; RAMAN-SPECTROSCOPY ; REPORTER GENES ; BIOLUMINESCENCE ; DYNAMICS ; TRACKING ; IDENTIFICATION ; COLONIZATION ; MICROBIOTA
摘要	Vast and complex intestinal communities are regulated and balanced through interactions with their host organisms, and disruption of gut microbial balance can cause a variety of diseases. Studying the mechanisms of pathogenic intestinal flora in the host and early detection of bacterial translocation and colonization can guide clinical diagnosis, provide targeted treatments, and improve patient prognosis. The use of in vivo imaging techniques to track microorganisms in the intestine, and study structural and functional changes of both cells and proteins, may clarify the governing equilibrium between the flora and host. Despite the recent rapid development of in vivo imaging of intestinal microecology, determining the ideal methodology for clinical use remains a challenge. Advances in optics, computer technology, and molecular biology promise to expand the horizons of research and development, thereby providing exciting opportunities to study the spatio-temporal dynamics of gut microbiota and the origins of disease. Here, this study reviews the characteristics and problems associated with optical imaging techniques, including bioluminescence, conventional fluorescence, novel metabolic labeling methods, nanomaterials, intelligently activated imaging agents, and photoacoustic (PA) imaging. It hopes to provide a valuable theoretical basis for future bio-intelligent imaging of intestinal bacteria.
资助项目	National Natural Science Foundation of China; Natural Science Foundation of Zhejiang Province [LD21H030002]; [82070593]
出版者	WILEY
ISSN	1613-4125
EISSN	1613-4133
卷号	68 期号:7
DOI	10.1002/mnfr.202300760
页数	9
WOS类目	Food Science & Technology
WOS研究方向	Food Science & Technology
WOS记录号	WOS:001185638800001
收录类别	SCIE ; PUBMED ; SCOPUS
在线发表日期	2024-03
URL	查看原文
PubMed ID	38491399
SCOPUSEID	2-s2.0-85187677679
通讯作者地址	[Chen, Yongping]Hepatology Diagnosis and Treatment Center,The First Affiliated Hospital of Wenzhou Medical University & Zhejiang Provincial Key Laboratory for Accurate Diagnosis and Treatment of Chronic Liver Diseases,Ouhai District, Zhejiang,Wenzhou,325035,China ; [Xu, Liang]Key Laboratory of Laboratory Medicine,Ministry of Education,School of Laboratory Medicine and Life Sciences,Wenzhou Medical University,Zhejiang,Wenzhou,325035,China
Scopus学科分类	Biotechnology;Food Science
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/209860
专题	附属第一医院检验医学院（生命科学学院、生物学实验教学中心）阿尔伯塔学院
通讯作者	Xu, Liang; Chen, Yongping
作者单位	1.Hepatology Diagnosis and Treatment Center,The First Affiliated Hospital of Wenzhou Medical University & Zhejiang Provincial Key Laboratory for Accurate Diagnosis and Treatment of Chronic Liver Diseases,Ouhai District, Zhejiang,Wenzhou,325035,China; 2.The First Affiliated Hospital of Wenzhou Medical University,Ouhai District, Zhejiang,Wenzhou,325035,China; 3.Alberta Institute,Wenzhou Medical University,Ouhai District, Zhejiang,Wenzhou,325035,China; 4.Key Laboratory of Laboratory Medicine,Ministry of Education,School of Laboratory Medicine and Life Sciences,Wenzhou Medical University,Zhejiang,Wenzhou,325035,China
第一作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院; 检验医学院（生命科学学院、生物学实验教学中心）
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Pan, Tongtong,Su, Lihuang,Zhang, Yiying,et al. Advances in Bio-Optical Imaging Systems for Spatiotemporal Monitoring of Intestinal Bacteria[J]. MOLECULAR NUTRITION & FOOD RESEARCH,2024,68(7).
APA	Pan, Tongtong, Su, Lihuang, Zhang, Yiying, Xu, Liang, & Chen, Yongping. (2024). Advances in Bio-Optical Imaging Systems for Spatiotemporal Monitoring of Intestinal Bacteria. MOLECULAR NUTRITION & FOOD RESEARCH, 68(7).
MLA	Pan, Tongtong,et al."Advances in Bio-Optical Imaging Systems for Spatiotemporal Monitoring of Intestinal Bacteria".MOLECULAR NUTRITION & FOOD RESEARCH 68.7(2024).