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TitleA classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography
Creator
Date Issued2024-12-31
Source PublicationANNALS OF MEDICINE   Impact Factor & Quartile
language英语
Original Document TypeArticle
KeywordIdiopathic macular epiretinal membrane iERM foveal avascular zone pars plana vitrectomy optical coherence tomography optical coherence tomography angiography
WOS KeywordINTERNAL LIMITING MEMBRANE ; INNER NUCLEAR LAYER ; PROGNOSTIC-FACTORS ; MULLER CELLS ; SURGERY ; MICROVASCULATURE
AbstractObjectiveTo evaluate the characteristics and prognoses of idiopathic macular epiretinal membrane (iERM) using a classification based on the foveal avascular zone (FAZ) area.MethodIERMs were classified into four stages based on the FAZ area. Baseline FAZ-related parameters, pre-and postoperative central macular thickness (CMT), and best corrected visual acuity (BCVA) were observed and compared between different stages. The correlations of structural parameters with pre-and postoperative logMAR BCVA were analyzed.Results162 iERM eyes were enrolled, including 105 eyes followed up for 12 months after surgery. The preoperative BCVA was better at the early stage. Postoperative BCVA at Stages 2 and 3 were better compared to Stage 4. The early stage was associated with thinner CMT pre-and postoperatively. However, there was no significant difference in CMT between postoperative Stages 1 and 2 or Stages 3 and 4. Preoperative logMAR BCVA was negatively correlated with FAZ area, perimeter, and FD-300 and was positively correlated with CMT and acircularity index (AI). CMT correlated positively with BCVA for each stage, except Stage 4; FAZ area, perimeter, and FD-300 had a negative correlation at Stage 1. Baseline BCVA and CMT positively correlated with BCVA at the last follow-up, while FAZ area and FD-300 were negatively correlated. Baseline BCVA had a positive correlation for each stage, except Stage 1; FD-300 had a negative correlation at Stages 2 and 3; CMT had a positive correlation at Stage 3.ConclusionA classification based on the FAZ area was established innovatively. This classification can reflect the progression of iERM and is helpful to the postoperative prognosis. (1) Classification based on FAZ area facilitate automation and consistency compared to the previous OCT-based qualitative grading.(2) With baseline FAZ stage advanced, thickened CMT and worsened BCVA was observed at baseline and 1-year post-operation. (3) Baseline FAZ area and FD-300 negatively correlated with logMAR BCVA at the last follow-up, reflecting the nonnegligible prognostic impact of macular vascular changes.
Funding ProjectZhejiang Medical Health Science and Technology Project [2023KY490]; Natural Science Foundation of Zhejiang Province [LTGY23H120005]
PublisherTAYLOR & FRANCIS LTD
ISSN0785-3890
EISSN1365-2060
Volume56Issue:1
DOI10.1080/07853890.2024.2316008
Page Number9
WOS SubjectMedicine, General & Internal
WOS Research AreaGeneral & Internal Medicine
WOS IDWOS:001187544500001
Indexed BySCIE ; PUBMED ; SCOPUS
URL查看原文
PubmedId38502921
scopusid2-s2.0-85188317834
Corresponding author address[Shen, Lijun]Department of Ophthalmology Center,Zhejiang Provincial People’s Hospital,Affiliated Hospital of Hangzhou Medical College,158 Shangtang Road, Zhejiang,Hangzhou,China
scopus subject classificationMedicine (all)
Citation statistics
Document TypeJournal article
Identifierhttps://kms.wmu.edu.cn/handle/3ETUA0LF/209572
CollectionWenzhou Med Univ, Sch Biomed Engn, Sch Ophthalmol & Optometry, Hosp Eye
Corresponding AuthorShen, Lijun
Affiliation
1.School of Ophthalmology and Optometry,Wenzhou Medical University,Wenzhou,China;
2.Department of Ophthalmology Center,Zhejiang Provincial People’s Hospital,Affiliated Hospital of Hangzhou Medical College,Hangzhou,China;
3.Affiliated Eye Hospital of Wenzhou Medical University,Hangzhou,China;
4.Yongkang Hospital,Yongkang,China;
5.Chicago College of Optometry,Midwestern University,Downers Grove,United States
First Author AffilicationWenzhou Med Univ, Sch Biomed Engn, Sch Ophthalmol & Optometry, Hosp Eye
First Signature AffilicationWenzhou Med Univ, Sch Biomed Engn, Sch Ophthalmol & Optometry, Hosp Eye
Recommended Citation
GB/T 7714
Zhang, Zhengxi,Mao, Jianbo,Lao, Jimeng,et al. A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography[J]. ANNALS OF MEDICINE,2024,56(1).
APA Zhang, Zhengxi., Mao, Jianbo., Lao, Jimeng., Deng, Xinyi., Fang, Yuyan., ... & Shen, Lijun. (2024). A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography. ANNALS OF MEDICINE, 56(1).
MLA Zhang, Zhengxi,et al."A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography".ANNALS OF MEDICINE 56.1(2024).

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