A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography

doi:10.1080/07853890.2024.2316008

科研成果详情

题名	A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography
作者	Zhang, Zhengxi 1; Mao, Jianbo 2; Lao, Jimeng1,3; Deng, Xinyi 1,2; Fang, Yuyan 1,4; Chen, Nuo1; Liu, Chenyi1,5; Chen, Yiqi 2; Shen, Lijun 2
发表日期	2024-12-31
发表期刊	ANNALS OF MEDICINE 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Idiopathic macular epiretinal membrane iERM foveal avascular zone pars plana vitrectomy optical coherence tomography optical coherence tomography angiography
其他关键词	INTERNAL LIMITING MEMBRANE ; INNER NUCLEAR LAYER ; PROGNOSTIC-FACTORS ; MULLER CELLS ; SURGERY ; MICROVASCULATURE
摘要	ObjectiveTo evaluate the characteristics and prognoses of idiopathic macular epiretinal membrane (iERM) using a classification based on the foveal avascular zone (FAZ) area.MethodIERMs were classified into four stages based on the FAZ area. Baseline FAZ-related parameters, pre-and postoperative central macular thickness (CMT), and best corrected visual acuity (BCVA) were observed and compared between different stages. The correlations of structural parameters with pre-and postoperative logMAR BCVA were analyzed.Results162 iERM eyes were enrolled, including 105 eyes followed up for 12 months after surgery. The preoperative BCVA was better at the early stage. Postoperative BCVA at Stages 2 and 3 were better compared to Stage 4. The early stage was associated with thinner CMT pre-and postoperatively. However, there was no significant difference in CMT between postoperative Stages 1 and 2 or Stages 3 and 4. Preoperative logMAR BCVA was negatively correlated with FAZ area, perimeter, and FD-300 and was positively correlated with CMT and acircularity index (AI). CMT correlated positively with BCVA for each stage, except Stage 4; FAZ area, perimeter, and FD-300 had a negative correlation at Stage 1. Baseline BCVA and CMT positively correlated with BCVA at the last follow-up, while FAZ area and FD-300 were negatively correlated. Baseline BCVA had a positive correlation for each stage, except Stage 1; FD-300 had a negative correlation at Stages 2 and 3; CMT had a positive correlation at Stage 3.ConclusionA classification based on the FAZ area was established innovatively. This classification can reflect the progression of iERM and is helpful to the postoperative prognosis. (1) Classification based on FAZ area facilitate automation and consistency compared to the previous OCT-based qualitative grading.(2) With baseline FAZ stage advanced, thickened CMT and worsened BCVA was observed at baseline and 1-year post-operation. (3) Baseline FAZ area and FD-300 negatively correlated with logMAR BCVA at the last follow-up, reflecting the nonnegligible prognostic impact of macular vascular changes.
资助项目	Zhejiang Medical Health Science and Technology Project [2023KY490]; Natural Science Foundation of Zhejiang Province [LTGY23H120005]
出版者	TAYLOR & FRANCIS LTD
ISSN	0785-3890
EISSN	1365-2060
卷号	56 期号:1
DOI	10.1080/07853890.2024.2316008
页数	9
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
WOS记录号	WOS:001187544500001
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
Pubmed记录号	38502921
Scopus记录号	2-s2.0-85188317834
通讯作者地址	[Shen, Lijun]Department of Ophthalmology Center,Zhejiang Provincial People’s Hospital,Affiliated Hospital of Hangzhou Medical College,158 Shangtang Road, Zhejiang,Hangzhou,China
scopus学科分类	Medicine (all)
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/209572
专题	眼视光学院（生物医学工程学院）、附属眼视光医院
通讯作者	Shen, Lijun
作者单位	1.School of Ophthalmology and Optometry,Wenzhou Medical University,Wenzhou,China; 2.Department of Ophthalmology Center,Zhejiang Provincial People’s Hospital,Affiliated Hospital of Hangzhou Medical College,Hangzhou,China; 3.Affiliated Eye Hospital of Wenzhou Medical University,Hangzhou,China; 4.Yongkang Hospital,Yongkang,China; 5.Chicago College of Optometry,Midwestern University,Downers Grove,United States
第一作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
第一作者的第一单位	眼视光学院（生物医学工程学院）、附属眼视光医院
推荐引用方式 GB/T 7714	Zhang, Zhengxi,Mao, Jianbo,Lao, Jimeng,et al. A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography[J]. ANNALS OF MEDICINE,2024,56(1).
APA	Zhang, Zhengxi., Mao, Jianbo., Lao, Jimeng., Deng, Xinyi., Fang, Yuyan., ... & Shen, Lijun. (2024). A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography. ANNALS OF MEDICINE, 56(1).
MLA	Zhang, Zhengxi,et al."A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography".ANNALS OF MEDICINE 56.1(2024).