Dose-response association between 24-hour total movement activity and testosterone deficiency in adult males

doi:10.3389/fendo.2023.1280841

科研成果详情

题名	Dose-response association between 24-hour total movement activity and testosterone deficiency in adult males
作者	Wu, Shenghao1; Chen, Wu 2; Cai, Yaoyao3; Xia, Weiting4
发表日期	2024-01-12
发表期刊	FRONTIERS IN ENDOCRINOLOGY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	male health physical activity testosterone deficiency NHANES accelerometer data
其他关键词	PHYSICAL-ACTIVITY ; SEX-HORMONES ; MEN ; EXERCISE
摘要	Background and objectives Previous studies on the relationship between physical activity and testosterone are limited and controversial. Hence we investigated whether high level of physical activity is associated with a low risk of testosterone deficiency (TD). Methods This cross-sectional analysis was conducted in a representative sample of US adult males who participated in the 2011-2014 cycle of the National Health and Nutrition Examination Survey (NHANES). We used the monitor independent movement summary (MIMS) to assess activity intensity, a novel physical activity metrics developed using raw data collected by accelerometers. Multivariable regression and smooth curve fitting was used to describe the relationships between physical activity and TD, and segmented regression model were used to analyze the threshold effect between them. Sensitivity analysis was conducted using interaction and stratified analysis. Results A U-shaped relationship between daily MIMS units and risk of TD was observed. The optimal value of daily MIMS units for the lowest risk of TD was 14.77 (x103), the risk of TD decreased by 5% in patients per unit increase of daily MIMS units when daily MIMS units <14.77 (x103) (adjusted OR = 0.95, 95%CI: 0.91, 0.99), but increased by 12% per unit increase of daily MIMS units when daily MIMS units >= 14.77 (x103) (adjusted OR = 1.12, 95%CI: 1.01, 1.23). In sensitivity analyses, the threshold effect was also similar according to baseline characteristics (P-interaction >0.05). Conclusion In a nationally representative sample of US adult males, light to moderate intensity physical activity is associated with a lower odds of TD, while high-intensity physical activity is associated with a higher risk of TD.
出版者	FRONTIERS MEDIA SA
ISSN	1664-2392
卷号	14
DOI	10.3389/fendo.2023.1280841
页数	10
WOS类目	Endocrinology & Metabolism
WOS研究方向	Endocrinology & Metabolism
WOS记录号	WOS:001150651700001
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	38283748
SCOPUSEID	2-s2.0-85183174253
通讯作者地址	[Xia, Weiting]Department of Gynecology,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China
Scopus学科分类	Endocrinology, Diabetes and Metabolism
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/207176
专题	第二临床医学院、附属第二医院、育英儿童医院附属第二医院附属第一医院_产科第一临床医学院（信息与工程学院）、附属第一医院_妇产科学_妇科
通讯作者	Xia, Weiting
作者单位	1.Reproductive Medicine Center,Department of Obstetrics and Gynecology,The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China; 2.Urology Department of Wenzhou People’s Hospital,The Third Affiliated Hospital of Shanghai University,Zhejiang,Wenzhou,China; 3.Department of Obstetrics,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China; 4.Department of Gynecology,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China
第一作者单位	第二临床医学院，附属第二医院、育英儿童医院; 附属第二医院; 妇产科
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
第一作者的第一单位	第二临床医学院，附属第二医院、育英儿童医院
推荐引用方式 GB/T 7714	Wu, Shenghao,Chen, Wu,Cai, Yaoyao,et al. Dose-response association between 24-hour total movement activity and testosterone deficiency in adult males[J]. FRONTIERS IN ENDOCRINOLOGY,2024,14.
APA	Wu, Shenghao, Chen, Wu, Cai, Yaoyao, & Xia, Weiting. (2024). Dose-response association between 24-hour total movement activity and testosterone deficiency in adult males. FRONTIERS IN ENDOCRINOLOGY, 14.
MLA	Wu, Shenghao,et al."Dose-response association between 24-hour total movement activity and testosterone deficiency in adult males".FRONTIERS IN ENDOCRINOLOGY 14(2024).