The effects of an enteral nutrition feeding protocol on critically ill patients: A prospective multi-center, before-after study

doi:10.1016/j.jcrc.2020.01.018

科研成果详情

题名	The effects of an enteral nutrition feeding protocol on critically ill patients: A prospective multi-center, before-after study
作者	Jiang, Libing 1; Huang, Xiaoxia 2; Wu, Chunshuang 1; Tang, Jiaying 2; Li, Qiang 1; Feng, Xiuqin 2; He, Tao 3; Wang, Zhengquan 4; Gao, Jindan 4; Ruan, Zhanwei 5; Hong, Weili 5; Lai, Dengpan 6; Zhao, Fei 6; Huang, Zhiping 7; Lu, Zhifeng 7; Tang, Weidong 8; Zhu, Lijun 8; Zhang, Bingwen 9; Wang, Zhi 9; Shen, Xiaoyuan 10; Lai, Jiawei 10; Ji, Zhaohui 11; Fu, Kai 11; Hong, Yucai 12; Dai, Junru 12; Hong, Guangliang13; Xu, Wenqing 13; Wang, Yi 14; Xie, Yun 14; Chen, Yuxi 15; Zhu, Xiuhua 15; Ding, Guojuan 16; Gu, Lanru 16; Zhang, Mao 1
发表日期	2020-04
发表期刊	JOURNAL OF CRITICAL CARE 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Critically ill Enteral nutrition Protocol Calorie
其他关键词	INTENSIVE-CARE-UNIT ; SUPPORT PROTOCOL ; ICU PATIENTS ; IMPLEMENTATION ; OUTCOMES ; GUIDELINES ; IMPACT ; MORTALITY ; DELIVERY ; THERAPY
摘要	Purpose: The aim of this study was to explore the effects of an enteral nutrition (EN) feeding protocol in critically ill patients. Methods: This was a prospective multi-center before-after study. We compared energy related and prognostic indicators between the control group (pre-implementation stage) and intervention group (post-implementation stage). The primary endpoint was the percentage of patients receiving EN within 7 days after ICU admission. Results: 209 patients in the control group and 230 patients in the intervention group were enrolled. The implementation of the EN protocol increased the percentage of target energy reached from day 3 to day 7, and the difference between two groups reached statistical significance in day 6 (P = .01) and day 7 (P = .002). But it had no effects on proportion of patient receiving EN (P = .65) and start time of EN (P = .90). The protocol application might be associated with better hospital survival (89.1% vs 82.8%, P = .055) and reduce the incidence of EN related adverse (P = .004). There was no difference in ICU length of stay, duration of mechanical ventilation and ICU cost. Conclusion: The implementation of the enteral feeding protocol is associated with improved energy intake and a decreased incidence of enteral nutrition related adverse events for critically ill patients, but it had no statistically beneficial effects on reducing the hospital mortality rate. (C) 2020 Elsevier Inc. All rights reserved.
资助项目	Zhejiang medical and health science and technology project [2014kyA091, 2017ky372]; Zhejiang Education Department [Y201738058]
出版者	W B SAUNDERS CO-ELSEVIER INC
出版地	PHILADELPHIA
ISSN	0883-9441
EISSN	1557-8615
卷号	56 页码:249-256
DOI	10.1016/j.jcrc.2020.01.018
页数	8
WOS类目	Critical Care Medicine
WOS研究方向	General & Internal Medicine
WOS记录号	WOS:000519555700040
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
Pubmed记录号	31986368
Scopus记录号	2-s2.0-85078199044
通讯作者地址	[Zhang, Mao]Department of Emergency Medicine,The Second Affiliated Hospital,Zhejiang University School of Medicine,No 88, Jiefang Rd,Hangzhou,China
scopus学科分类	Critical Care and Intensive Care Medicine
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/20516
专题	第一临床医学院（信息与工程学院）、附属第一医院_急诊医学附属第一医院
通讯作者	Zhang, Mao
作者单位	1.Department of Emergency Medicine,The Second Affiliated Hospital,Zhejiang University School of Medicine,No 88, Jiefang Rd,Hangzhou,China; 2.Department of Nursing,The Second Affiliated Hospital Zhejiang University School of Medicine,No 88, Jiefang Rd,Hangzhou,China; 3.Department of Emergency Intensive Care Unit,The Second Hospital of Jiaxing,No 1518, Huanchengbei Rd,Jiaxing,China; 4.Department of Emergency Medicine,Yuyao People's Hospital,Medical School of Ningbo University,Ningbo,China; 5.Department of Emergency Intensive Care Unit,Ruian people's Hospital,Ruian,China; 6.Emergency Department,The Affiliated Hospital of Hangzhou Normal University,Hangzhou,China; 7.Department of Critical Care Medicine,Beilun District People's Hospital,Ningbo,China; 8.Department of Critical Care Medicine,The First People's Hospital of Fuyang district,Hangzhou,China; 9.Emergency Department,Jinhua Hospital of Zhejiang University,Jinhua,China; 10.Department of Critical Care Medicine,The First People's Hospital of Xiaoshan District,Hangzhou,China; 11.Emergency Department,The First People's Hospital of Huzhou,Huzhou,China; 12.Department of Emergency Medicine,Sir Run-Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou,China; 13.Department of Emergency Medicine,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 14.Department of Emergency Medicine,The First People's Hospital of Hangzhou,Hangzhou,China; 15.Department of Emergency Medicine,Wenzhou Central Hospital,Wenzhou,China; 16.Department of Emergency Medicine,People's Hospital of Shaoxing,Shaoxing,China
推荐引用方式 GB/T 7714	Jiang, Libing,Huang, Xiaoxia,Wu, Chunshuang,et al. The effects of an enteral nutrition feeding protocol on critically ill patients: A prospective multi-center, before-after study[J]. JOURNAL OF CRITICAL CARE,2020,56:249-256.
APA	Jiang, Libing., Huang, Xiaoxia., Wu, Chunshuang., Tang, Jiaying., Li, Qiang., ... & Zhang, Mao. (2020). The effects of an enteral nutrition feeding protocol on critically ill patients: A prospective multi-center, before-after study. JOURNAL OF CRITICAL CARE, 56, 249-256.
MLA	Jiang, Libing,et al."The effects of an enteral nutrition feeding protocol on critically ill patients: A prospective multi-center, before-after study".JOURNAL OF CRITICAL CARE 56(2020):249-256.