A prospective study of waist circumference trajectories and incident cardiovascular disease in China: the Kailuan Cohort Study

doi:10.1093/ajcn/nqaa331

科研成果详情

题名	A prospective study of waist circumference trajectories and incident cardiovascular disease in China: the Kailuan Cohort Study
作者	Wang, Liang 1; Lee, Yujin 2; Wu, Yuntao 3; Zhang, Xinyuan 4; Jin, Cheng 3; Huang, Zhe 3; Wang, Yixin 5; Wang, Zhiyi6; Kris-Etherton, Penny 4; Wu, Shouling 3; Gao, Xiang 4
发表日期	2021-02
发表期刊	AMERICAN JOURNAL OF CLINICAL NUTRITION 影响因子和分区
语种	英语
原始文献类型	Article
关键词	waist circumference abdominal fat mass cardiovascular disease epidemiology trajectory analysis
其他关键词	BODY-MASS INDEX ; MYOCARDIAL-INFARCTION RISK ; CARDIOMETABOLIC RISK ; OBESITY ; ADULTS ; MORTALITY ; HEALTH ; ASSOCIATION ; GENDER ; POPULATION
摘要	Background: Single measurements of waist circumference (WC) predict the incident cardiovascular disease (CVD); however, long-term patterns of WC and their association with the incidence of CVD are poorly characterized. Objective: We aimed to identify WC trajectories and determine their association with incident CVD (stroke and myocardial infarction) and examine whether the association persisted among individuals without obesity. Methods: We included 75.535 participants from a community-based cohort in China who were aged >18 y and free of stroke, coronary artery disease, and cancer in 2010 (the baseline). WC and other covariates were repeatedly measured in 2006. 2008, and 2010. WC trajectories were identified by latent mixture modeling. A Cox proportional hazards model was used to examine the association between WC trajectories and incident CVD, after adjustment for age, sex, income, education, systolic blood pressure, lipid profiles, plasma concentrations of glucose. C-reactive protein, smoking, and alcohol drinking. Results: We identified 4 WC trajectories based on 2006 WC measurement and change patterns during 2006-2010: low stable (n = 12,072; mean WC 74.1-75.1 cm), moderate stable (n = 41.750; mean WC 85.1-86.6 cm), moderate-high stable (n = 19,914; mean WC 95.6-97.2 cm), and high stable (n = 1,799; mean WC 106.3-110.9 cm). During 2010-2016, we documented 2819 incident CVD events. Compared with the low-stable group, groups with elevated WC trajectories had a higher risk of CVD events during 6 y of followup (2010-2016). Adjusted HRs (95% CIs) were 1.49 (1.21, 1.83) for the moderate stable group, 1.71(1.38, 2.12) for the moderate-high stable group, and 1.45 (1.06, 2.00) for the high stable group. After further adjusting for BMI or excluding obese participants, we observed similar results. The positive association between WC and incident CVD was higher in individuals who were aged <60 y (P-interaction < 0.0001). Conclusions: WC trajectory patterns were associated with altered risk of CVD among Chinese adults, even among people without BMI-defined obesity. When stratifying by age, the association was observed to be higher in younger adults.
出版者	OXFORD UNIV PRESS
出版地	OXFORD
ISSN	0002-9165
EISSN	1938-3207
卷号	113 期号:2 页码:338-347
DOI	10.1093/ajcn/nqaa331
页数	10
WOS类目	Nutrition & Dietetics
WOS研究方向	Nutrition & Dietetics
WOS记录号	WOS:000628690200012
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	33330917
SCOPUSEID	2-s2.0-85102222419
自科自定义期刊分类	T3(B)类
通讯作者地址	[Wang, Liang]Department of Public Health,Robbins College of Health and Human Sciences,Baylor University,Waco,United States ; [Wu, Shouling]Department of Cardiology,Kailuan General Hospital,Hebei United University,Tangshan,China
Scopus学科分类	Medicine (miscellaneous);Nutrition and Dietetics
TOP期刊	TOP期刊
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/20281
专题	第一临床医学院（信息与工程学院）、附属第一医院_急诊医学
通讯作者	Wang, Liang; Wu, Shouling
作者单位	1.Department of Public Health,Robbins College of Health and Human Sciences,Baylor University,Waco,United States; 2.Department of Food and Nutrition,Myongji University,Yongin,South Korea; 3.Department of Cardiology,Kailuan General Hospital,Hebei United University,Tangshan,China; 4.Department of Nutritional Sciences,Pennsylvania State University,University Park,United States; 5.Department of Nutrition,TH Chan School of Public Health,Harvard University,Boston,United States; 6.Department of Emergency Medicine and General Practice,Second Affiliated Hospital and Yuying Children's Hospital,Wenzhou Medical University,Wenzhou,China
推荐引用方式 GB/T 7714	Wang, Liang,Lee, Yujin,Wu, Yuntao,et al. A prospective study of waist circumference trajectories and incident cardiovascular disease in China: the Kailuan Cohort Study[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION,2021,113(2):338-347.
APA	Wang, Liang., Lee, Yujin., Wu, Yuntao., Zhang, Xinyuan., Jin, Cheng., ... & Gao, Xiang. (2021). A prospective study of waist circumference trajectories and incident cardiovascular disease in China: the Kailuan Cohort Study. AMERICAN JOURNAL OF CLINICAL NUTRITION, 113(2), 338-347.
MLA	Wang, Liang,et al."A prospective study of waist circumference trajectories and incident cardiovascular disease in China: the Kailuan Cohort Study".AMERICAN JOURNAL OF CLINICAL NUTRITION 113.2(2021):338-347.