Thymectomy in central lymph node dissection for papillary thyroid cancer

科研成果详情

题名	Thymectomy in central lymph node dissection for papillary thyroid cancer
作者	Huang, Du-Ping1; Ye, Xiao-He2; Xiang, You-Qun1; Zhang, Xiao-Hua 1
发表日期	2014-12-31
发表期刊	INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Thymectomy papillary thyroid cancer lymph node dissection
其他关键词	CENTRAL NECK DISSECTION ; THYMIC METASTASIS ; CARCINOMA ; COMPLICATIONS ; RECURRENCE ; MORBIDITY ; PATTERN
摘要	Background: Central lymph node dissection (CND) has been proposed in the treatment of patients affected by papillary thyroid cancer (PTC) with clinically negative neck lymph nodes. The procedure allows pathologic staging of lymph nodes of the central compartment and treatment of the micrometastases. By comparing bilateral and unilateral thymectomy during total thyroidectomy with central lymph node dissection for postoperative complications in sonographically node-negative papillary thyroid carcinomas, we aimed to determine the optimal extent of prophylactic central lymph node dissection. Methods: Patients were divided into two study groups: Group 1, total thyroidectomy plus unilateral thymectomy during the CND; Group 2, total thyroidectomy associated with bilateral thymectomy (both upper poles) during the CND. Primary endpoints of the study were evaluated by comparing the postoperative complications between the two groups. Results: The only significant result found when comparing the two groups was the rate of transient hypocalcemia. (Group 1: 13.7%, Group 2: 52.4%, p<0.01). A total of five cases of papillary thymic metastases were found in this study. And final pathology confirmed that all cases of thymic metastases were lymph node micrometastases of PTC, only situated in the ipsilateral thymus upper pole. Conclusions: Bilateral thymectomy during the CND did not provide a better carcinologic resection, as no contralateral thymic metastases were found. The unilateral thymectomy with total thyroidectomy during the CND may represent an effective strategy for reducing the rate of postoperative hypocalcemia.
出版者	E-CENTURY PUBLISHING CORP
出版地	MADISON
ISSN	1940-5901
卷号	7 期号:4 页码:1135-1139
页数	5
WOS类目	Medicine, Research & Experimental
WOS研究方向	Research & Experimental Medicine
WOS记录号	WOS:000336740600048
收录类别	SCIE ; PUBMED
URL	查看原文
PubMed ID	24955195
PMC记录号	PMC4057874
通讯作者地址	[Xiang, You-Qun]Wenzhou Med Coll, Affiliated Hosp 1, Dept Oncol, 2 Fu Xue Rd, Wenzhou 325000, Peoples R China.
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/19213
专题	附属第一医院_肿瘤内科第一临床医学院（信息与工程学院）、附属第一医院_影像医学与核医学_放射科
通讯作者	Xiang, You-Qun
作者单位	1.Wenzhou Med Coll, Affiliated Hosp 1, Dept Oncol, Wenzhou 325000, Peoples R China; 2.Wenzhou Med Coll, Affiliated Hosp 1, Dept Radiol, Wenzhou 325000, Peoples R China
第一作者单位	附属第一医院_肿瘤内科
通讯作者单位	附属第一医院_肿瘤内科
第一作者的第一单位	附属第一医院_肿瘤内科
推荐引用方式 GB/T 7714	Huang, Du-Ping,Ye, Xiao-He,Xiang, You-Qun,et al. Thymectomy in central lymph node dissection for papillary thyroid cancer[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2014,7(4):1135-1139.
APA	Huang, Du-Ping, Ye, Xiao-He, Xiang, You-Qun, & Zhang, Xiao-Hua. (2014). Thymectomy in central lymph node dissection for papillary thyroid cancer. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 7(4), 1135-1139.
MLA	Huang, Du-Ping,et al."Thymectomy in central lymph node dissection for papillary thyroid cancer".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 7.4(2014):1135-1139.