Recent advances in self-assembling peptide matrices as functional coatings for implantable devices

doi:10.3389/fchem.2022.1040499

科研成果详情

名称	Recent advances in self-assembling peptide matrices as functional coatings for implantable devices
作者	Tian, Yuan 1; Lu, Lei2
发表期刊	Frontiers in Chemistry;
语种	英语
原始文献类型	Short Survey
关键词	functional coatings implantable devices nanofiber self-assembling peptides surface modification
摘要	Nature has evolved numerous supramolecular machineries for modulating various cellular functions. Inspired by the assembly of these sophisticated structures in nature, the controlled assembly of synthetic peptides emerges as a promising approach to therapeutically relevant applications. The self-assembling biomimetic peptides could form well-ordered architectures through non-covalent interactions such as π-π stacking, van der Waals, electrostatic, and hydrogen bonding. In addition, the peptidic building blocks are highly biocompatible and allow facile chemical manipulation with diverse functionalities. For decades, a serious of engineered self-assembling peptides have been extensively studied as functional hydrogels for various applications. Meanwhile, the surface modification strategies based on self-assembling peptide matrices have also raised the attention of biomaterials researchers due to their programmability and 3D porous morphologies. This concise review will cover recent advances in self-assembling peptide matrices as functional coatings for implantable devices. The opportunities and challenges in this field will also be discussed.
资助项目	Sichuan Science and Technology Program[2021JDRC0160,2022NSFSC0385];Natural Science Foundation of China[21708031,51725303,82171026];China Postdoctoral Science Foundation[BX20180264];
出版者	Frontiers Media S.A.
ISSN	2296-2646
卷号	10
DOI	10.3389/fchem.2022.1040499
收录类别	SCOPUS
发布日期	2022-11-16
URL	查看原文
通讯作者地址	[Tian, Yuan]Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs,School of Life Science and Engineering,Southwest Jiaotong University,Chengdu,China ; [Lu, Lei]School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China
Scopus学科分类	Chemistry (all)
SCOPUSEID	SCOPUS_ID:85143227823
引用统计
文献类型	其他
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/184797
专题	口腔医学院、附属口腔医院
通讯作者	Tian, Yuan; Lu, Lei
作者单位	1.Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs,School of Life Science and Engineering,Southwest Jiaotong University,Chengdu,China; 2.School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China
通讯作者单位	口腔医学院、附属口腔医院
推荐引用方式 GB/T 7714	Tian, Yuan,Lu, Lei. Recent advances in self-assembling peptide matrices as functional coatings for implantable devices. 2022.