CORRELATIONS OF VISFATIN WITH SEVERITY OF ACUTE MYOCARDIAL INFARCTION, CARDIOVASCULAR RISK FACTORS AND ATRIAL FIBRILLATION AFTER PERCUTANEOUS CORONARY INTERVENTION

doi:10.5937/jomb0-41963

科研成果详情

题名	CORRELATIONS OF VISFATIN WITH SEVERITY OF ACUTE MYOCARDIAL INFARCTION, CARDIOVASCULAR RISK FACTORS AND ATRIAL FIBRILLATION AFTER PERCUTANEOUS CORONARY INTERVENTION
作者	Zhang, Huihui 1; Lei, Dingwei 2; Zhang, Miaolin 3; Tu, Sijia 1; Shen, Chaofeng 1; Lin, Fengxian4
发表日期	2023
发表期刊	JOURNAL OF MEDICAL BIOCHEMISTRY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	acute myocardial infarction visfatin cardiovascular risk factors atrial fibrillation
摘要	Background: To investigate the relationship between visfatin level in the peripheral blood of patients with acute myocardial infarction (AMI) patients and the severity of AMI, cardiovascular risk factors and atrial fibrillation after percutaneous coronary intervention (PCI).Methods: A total of 37 AMI patients diagnosed and treated in our hospital were selected as experimental group, and 35 patients with normal coronary angiography were enrolled as control group. The general pathological data and occurrence of atrial fibrillation after PCI of all the patients were recorded in detail, and the content of indexes related to the severity of AMI and visfatin was measured. Moreover, the correlations of visfatin with the severity of AMI, cardiovascular risk factors and atrial fibrillation after PCI were explored.Results: The differences in the levels of N-terminal pro-B type natriuretic peptide (NT-proBNP), cardiac troponin I (cTnI), myoglobin (MYO) and creatine kinase isoenzyme MB mass (CK-MBm) in the peripheral blood, left ventricular end-systolic diameter (LVEDs), left ventricular end-diastolic volume (LVEDV) and left ventricular ejection fraction (LVEF) were statistically significant between experimental group and control group. Furthermore, experimental group had a remarkably higher visfatin level in the peripheral blood than control group. The visfatin level in the peripheral blood was positively correlated with the severity of AMI and the cardiovascular risk factors, but it was negatively associated with atrial fibrillation after PCI.Conclusion: The visfatin level in the peripheral blood of AMI patients has close correlations with the severity of AMI, cardiovascular risk factors and atrial fibrillation after PCI. This study suggests that measuring the visfatin level in the peripheral blood of AMI patients can provide useful information on the severity of AMI, cardiovascular risk factors, and the likelihood of atrial fibrillation after PCI. Therefore, visfatin may serve as a potential biomarker for risk stratification and personalized treatment of AMI patients
出版者	SOC MEDICAL BIOCHEMISTS SERBIA
ISSN	1452-8258
EISSN	1452-8266
卷号	42 期号:4 页码:650-657
DOI	10.5937/jomb0-41963
页数	8
WOS类目	Biochemistry & Molecular Biology
WOS研究方向	Biochemistry & Molecular Biology
WOS记录号	WOS:001085480100012
收录类别	SCIE ; SCOPUS
URL	查看原文
PubMed ID	38084234
SCOPUSEID	2-s2.0-85177061727
通讯作者地址	[Lin, Fengxian]Department of Cardiovascular Medicine,The Third Affiliated Hospital of Wenzhou Medical University,108 Wansong Road, Ruian, Zhejiang,Wenzhou,325200,China
Scopus学科分类	Clinical Biochemistry;Biochemistry (medical)
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/183996
专题	附属第一医院其他_附属第三医院（瑞安市人民医院）
通讯作者	Lin, Fengxian
作者单位	1.Department of Cardiovascular Medicine,First People’s Hospital of Linping District,Hangzhou,China; 2.Department of Cardiovascular Medicine,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu,China; 3.Department of Orthopedic Surgery,First People’s Hospital of Linping District,Hangzhou,China; 4.Department of Cardiovascular Medicine,The Third Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
通讯作者单位	附属第三医院（瑞安市人民医院）
推荐引用方式 GB/T 7714	Zhang, Huihui,Lei, Dingwei,Zhang, Miaolin,et al. CORRELATIONS OF VISFATIN WITH SEVERITY OF ACUTE MYOCARDIAL INFARCTION, CARDIOVASCULAR RISK FACTORS AND ATRIAL FIBRILLATION AFTER PERCUTANEOUS CORONARY INTERVENTION[J]. JOURNAL OF MEDICAL BIOCHEMISTRY,2023,42(4):650-657.
APA	Zhang, Huihui, Lei, Dingwei, Zhang, Miaolin, Tu, Sijia, Shen, Chaofeng, & Lin, Fengxian. (2023). CORRELATIONS OF VISFATIN WITH SEVERITY OF ACUTE MYOCARDIAL INFARCTION, CARDIOVASCULAR RISK FACTORS AND ATRIAL FIBRILLATION AFTER PERCUTANEOUS CORONARY INTERVENTION. JOURNAL OF MEDICAL BIOCHEMISTRY, 42(4), 650-657.
MLA	Zhang, Huihui,et al."CORRELATIONS OF VISFATIN WITH SEVERITY OF ACUTE MYOCARDIAL INFARCTION, CARDIOVASCULAR RISK FACTORS AND ATRIAL FIBRILLATION AFTER PERCUTANEOUS CORONARY INTERVENTION".JOURNAL OF MEDICAL BIOCHEMISTRY 42.4(2023):650-657.