Association between body roundness index and non-alcoholic fatty liver disease detected by Fibroscan in America

doi:10.1002/jcla.24973

科研成果详情

题名	Association between body roundness index and non-alcoholic fatty liver disease detected by Fibroscan in America
作者	Jiang, Ningning 1; Zhang, Shengguo 2; Chu, Jinguo 3; Yang, Naibin 4; Lu, Mingqin5
发表日期	2023-10-18
发表期刊	JOURNAL OF CLINICAL LABORATORY ANALYSIS 影响因子和分区
语种	英语
原始文献类型	Article ; Early Access
关键词	body roundness index cross-sectional NAFLD NHANES
其他关键词	EPIDEMIOLOGY ; PREVALENCE
摘要	BackgroundThe prevalence of non-alcoholic fatty liver disease (NAFLD) and obesity is worldwide on the rise. Body roundness index (BRI), as a newly developed anthropometric indicator, has been recently reported to identify obesity. However, it is still unclear whether BRI is associated with the prevalence of NAFLD.MethodsData were from the National Health and Nutrition Examination Survey (NHANES) 2017-2018. NAFLD was diagnosed based on hepatic steatosis defined by CAP values >= 274 dB/m. Multivariable logistic regression analysis was performed to detect the association between BRI and the odds of NAFLD. Subgroup analysis stratified by age, gender, BMI, and race was further conducted. To explore the potential ability of BRI in predicting NAFLD, the area under the curve (AUC) of BRI was calculated by receiver operating characteristic (ROC) analysis.ResultsAmong the 4467 study participants, 1718 (38.5%) were diagnosed with NAFLD. Compared to the non-NAFLD group, participants with NAFLD had a higher level of BRI. The positive associations between BRI and NAFLD were detected in all three models (mode 1: OR = 1.71, 95% CI: 1.65-1.78, p < 0.0001; mode 2: OR = 1.78, 95% CI: 1.71-1.86, p < 0.0001; mode3: OR = 1.23, 95% CI: 1.11-1.35, p < 0.0001). The positive association steadily existed in different subgroups after stratified by age, gender, and BMI. Moreover, the non-linear association between BRI and NAFLD was detected, presenting inverted U-shaped curves. Furthermore, BRI had a high predictive value (AUC = 0.807) in identifying NAFLD.ConclusionsBRI was positively associated with the prevalence of NAFLD among individuals in America, regardless of age, gender, and BMI. Besides, BRI presented a high ability for identifying NAFLD.
资助项目	The authors thank the staff and the participants of the NHANES study for their valuable contributions.
出版者	WILEY
ISSN	0887-8013
EISSN	1098-2825
卷号	37 期号:19-20
DOI	10.1002/jcla.24973
页数	9
WOS类目	Medical Laboratory Technology
WOS研究方向	Medical Laboratory Technology
WOS记录号	WOS:001090887000001
收录类别	SCIE ; PUBMED ; SCOPUS
在线发表日期	2023-10
URL	查看原文
PubMed ID	37850486
SCOPUSEID	2-s2.0-85174246476
通讯作者地址	[Chu, Jinguo]Department of General Medicine,The First Affiliated Hospital of Ningbo University,Ningbo,China ; [Yang, Naibin]Department of Hepatology and Infectious Diseases,The First Affiliated Hospital of Ningbo University,No. 59 Liuting Street, Haishu District, Zhejiang,Ningbo,315010,China ; [Lu, Mingqin]Department of Infectious Diseases,The First Affiliated Hospital of Wenzhou Medical University,No. 1 Nanbaixiang Street, Ouhai District, Zhejiang,Wenzhou,325000,China
Scopus学科分类	Immunology and Allergy;Hematology;Public Health, Environmental and Occupational Health;Clinical Biochemistry;Medical Laboratory Technology;Biochemistry (medical);Microbiology (medical)
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/183570
专题	附属第一医院其他_附属第三医院（瑞安市人民医院）
通讯作者	Chu, Jinguo; Yang, Naibin; Lu, Mingqin
作者单位	1.Department of Internal Medicine,The Second Hospital of Ninghai City,Chengguan Hospital of Ninghai City,Zhejiang,Ningbo,China; 2.Department of Infection,the Third Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China; 3.Department of General Medicine,The First Affiliated Hospital of Ningbo University,Zhejiang,Ningbo,China; 4.Department of Hepatology and Infectious Diseases,The First Affiliated Hospital of Ningbo University,Zhejiang,Ningbo,China; 5.Department of Infectious Diseases,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
推荐引用方式 GB/T 7714	Jiang, Ningning,Zhang, Shengguo,Chu, Jinguo,et al. Association between body roundness index and non-alcoholic fatty liver disease detected by Fibroscan in America[J]. JOURNAL OF CLINICAL LABORATORY ANALYSIS,2023,37(19-20).
APA	Jiang, Ningning, Zhang, Shengguo, Chu, Jinguo, Yang, Naibin, & Lu, Mingqin. (2023). Association between body roundness index and non-alcoholic fatty liver disease detected by Fibroscan in America. JOURNAL OF CLINICAL LABORATORY ANALYSIS, 37(19-20).
MLA	Jiang, Ningning,et al."Association between body roundness index and non-alcoholic fatty liver disease detected by Fibroscan in America".JOURNAL OF CLINICAL LABORATORY ANALYSIS 37.19-20(2023).