Development of in-situ Zn–3Cu–10ZnO composite prepared by high-pressure solidification for orthopedic applications

doi:10.1016/j.jmrt.2023.08.286

科研成果详情

题名	Development of in-situ Zn–3Cu–10ZnO composite prepared by high-pressure solidification for orthopedic applications
作者	Cai, Wenhao 1; Tong, Xian2; Zhang, Dechuang 1; Guo, Lin 1; Lin, Jixing2; Lin, Jianguo 1
发表日期	2023-10
发表期刊	Journal of Materials Research and Technology 影响因子和分区
语种	英语
原始文献类型	Journal article (JA)
关键词	Biodegradability Corrosion rate Electrochemical corrosion II-VI semiconductors Powder metallurgy Powder metals Zinc oxide Bone implant Degradability High pressure solidifications Implant materials In-situ synthesis Metal phase Orthopaedic applications Orthopaedic implants Solidification process Zinc-based composite
其他关键词	MAGNESIUM MATRIX COMPOSITES ; MECHANICAL-PROPERTIES ; CORROSION BEHAVIOR ; ALLOY ; ZINC ; MG ; MICROSTRUCTURE ; TEMPERATURE ; REMOVAL ; COPPER
摘要	Biodegradable zinc (Zn)-based composites are considered to be the next generation of promising orthopedic implant materials due to their degradability and the multiple functionality of combining metal and ceramic phases. However, its clinical bone-implant application is seriously limited due to their poor interface binding ability and mechanical properties. Herein, we developed the biodegradable in-situ Zn–3Cu–10ZnO composite through powder metallurgy using Zn and copper (Cu) powder combined with hot forging, followed by the high-pressure solidification (HPS) process for bone-implant application. Microstructural characterization showed that the HPS process can densify composite, form a uniform distribution of fine ZnO particle, and increase Cu atom solid solubility in the Zn matrix. Mechanical test revealed that the HPS composite exhibited a high compression performance with a compressive yield strength of 340.8 MPa, an ultimate compressive strength of 514.2 MPa, and a failure strain of ≥70%. The HPS composite exhibited the lowest corrosion rate of 25.8 μm/y and 44.3 μm/y measured by electrochemical corrosion and immersion tests, respectively, among these composites. Moreover, the diluted extracts of HPS composite with a concentration of ent% showed a higher cytocompatibility among these composites and better antimicrobial capability than those of the as-cast pure Zn. Accordingly, the HPS Zn–3Cu–10ZnO composite is expected to be a potential biodegradable material for orthopedic applications. © 2023
资助项目	National Natural Science Foundation of China [51971190, 11872053]; Post-graduate Scientific Research Innovation Project of Hunan Province [CX20210625]
出版者	Elsevier Editora Ltda
ISSN	2238-7854
EISSN	2214-0697
卷号	26 页码:5193-5208
DOI	10.1016/j.jmrt.2023.08.286
页数	16
WOS类目	Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
WOS记录号	WOS:001091746500001
收录类别	EI ; SCIE ; SCOPUS
在线发表日期	2023-09
EI入藏号	20233614695326
EI主题词	Compressive strength
EI分类号	539.1 Metals Corrosion ; 712.1 Semiconducting Materials ; 801.2 Biochemistry ; 801.4.1 Electrochemistry ; 802.2 Chemical Reactions ; 804.2 Inorganic Compounds
URL	查看原文
SCOPUSEID	2-s2.0-85169899369
通讯作者地址	[Lin, Jianguo]School of Materials Science and Engineering,Xiangtan University,Xiangtan,411105,China ; [Zhang, Dechuang]School of Materials Science and Engineering,Xiangtan University,Xiangtan,411105,China
Scopus学科分类	Ceramics and Composites;Biomaterials;Surfaces, Coatings and Films;Metals and Alloys
TOP期刊	TOP期刊
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/183110
专题	口腔医学院、附属口腔医院_口腔医学研究所
通讯作者	Zhang, Dechuang; Lin, Jianguo
作者单位	1.School of Materials Science and Engineering,Xiangtan University,Xiangtan,411105,China; 2.Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,325027,China
推荐引用方式 GB/T 7714	Cai, Wenhao,Tong, Xian,Zhang, Dechuang,et al. Development of in-situ Zn–3Cu–10ZnO composite prepared by high-pressure solidification for orthopedic applications[J]. Journal of Materials Research and Technology,2023,26:5193-5208.
APA	Cai, Wenhao, Tong, Xian, Zhang, Dechuang, Guo, Lin, Lin, Jixing, & Lin, Jianguo. (2023). Development of in-situ Zn–3Cu–10ZnO composite prepared by high-pressure solidification for orthopedic applications. Journal of Materials Research and Technology, 26, 5193-5208.
MLA	Cai, Wenhao,et al."Development of in-situ Zn–3Cu–10ZnO composite prepared by high-pressure solidification for orthopedic applications".Journal of Materials Research and Technology 26(2023):5193-5208.