Nomogram predicting overall prognosis for invasive micropapillary carcinoma of the breast: a SEER-based population study

doi:10.1136/bmjopen-2023-072632

科研成果详情

题名	Nomogram predicting overall prognosis for invasive micropapillary carcinoma of the breast: a SEER-based population study
作者	Liu, Jianpeng 1; Xi, Wei2; Zhou, Jiahao2; Gao, Wei2; Wu, Qiaolin2
发表日期	2023-08
发表期刊	BMJ OPEN 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Breast tumours Epidemiology Adult oncology
其他关键词	DUCTAL CARCINOMA ; AXILLARY NODE ; FOLLOW-UP ; SURVIVAL ; CANCER
摘要	ObjectivesThe prognosis of invasive micropapillary carcinoma (IMPC) of the breast is determined by many clinicopathological factors. This study aims to identify prognostic factors and develop reliable nomogram to predict the overall survival (OS) in patients with IMPC. DesignLog-rank test and Cox proportional hazards analysis were used to identify variables and construct a nomogram based on the training cohort. C-index and calibration curves were performed to evaluate the performance of the model in the training cohort and validation cohorts. SettingWe collected the patient data from the Surveillance, Epidemiology and End Results (SEER) database. This database holds data related to the cancer incidence from 18 population-based cancer registries in the USA. ParticipantsThe SEER database was used to screen 754 eligible patients as the study cohort. The whole cohort was randomly divided into a training cohort (n=377) and a validation cohort (n=377). ResultsAge at diagnosis, hormone receptors, number of positive regional lymph nodes and clinical stage were independent prognostic factors for patients with IMPC. The calibration curves presented excellent consistency between the actual and nomogram-predict survival probabilities in the training and validation cohorts. The C-index values of the nomogram were 0.794 and 0.774 for OS in the training and validation cohorts, respectively. ConclusionsThe novel nomogram provides new insights of the risk of each prognostic factor and can assist doctors in predicting the 1-year, 3-year and 5-year OS in patients with IMPC.
资助项目	hospital incubation funding project of the First Affiliated Hospital of Wenzhou Medical University [FHY2019064]
出版者	BMJ PUBLISHING GROUP
ISSN	2044-6055
卷号	13 期号:8
DOI	10.1136/bmjopen-2023-072632
页数	7
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
WOS记录号	WOS:001044964800026
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	37550031
SCOPUSEID	2-s2.0-85166784877
通讯作者地址	[Wu, Qiaolin]Anesthesiology,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China
Scopus学科分类	Medicine (all)
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/182383
专题	附属第一医院附属第一医院_麻醉科
通讯作者	Wu, Qiaolin
作者单位	1.Departments of Pathology,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China; 2.Anesthesiology,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China
第一作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Liu, Jianpeng,Xi, Wei,Zhou, Jiahao,et al. Nomogram predicting overall prognosis for invasive micropapillary carcinoma of the breast: a SEER-based population study[J]. BMJ OPEN,2023,13(8).
APA	Liu, Jianpeng, Xi, Wei, Zhou, Jiahao, Gao, Wei, & Wu, Qiaolin. (2023). Nomogram predicting overall prognosis for invasive micropapillary carcinoma of the breast: a SEER-based population study. BMJ OPEN, 13(8).
MLA	Liu, Jianpeng,et al."Nomogram predicting overall prognosis for invasive micropapillary carcinoma of the breast: a SEER-based population study".BMJ OPEN 13.8(2023).