Application of topical pharyngeal anesthesia to reduce adverse reactions during painless gastroscopy: A prospective randomized study

doi:10.3233/THC-220516

科研成果详情

题名	Application of topical pharyngeal anesthesia to reduce adverse reactions during painless gastroscopy: A prospective randomized study
作者	Lin, Xiaoxiao; Sun, Haoyue; Lin, Xizhou; Liu, Ya; Hu, Sisi; Yu, Yingcong; Song, Caiyun
发表日期	2023
发表期刊	TECHNOLOGY AND HEALTH CARE 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Topical pharyngeal anesthesia adverse reactions painless gastroscopy intravenous anesthesia
其他关键词	GASTROINTESTINAL ENDOSCOPY ; DOUBLE-BLIND ; SEDATION ; LIDOCAINE ; ANALGESIA ; PROPOFOL ; SAFETY ; MASK
摘要	BACKGROUND: Studies have reported that certain adverse reactions can occur during painless gastroscopy examination. Knowing how to decrease the risks and incidence of adverse reactions is of great importance. OBJECTIVE: To investigate whether topical pharyngeal anesthesia combined with intravenous anesthesia is superior to intravenous anesthesia alone in patients undergoing painless gastroscopy and to determine whether this combined approach had any additional benefits. METHODS: Three hundred patients undergoing painless gastroscopy were randomly assigned to either the control group or the experimental group. In the control group, patients were anesthetized with propofol, while patients in the experimental group received propofol combined with 2% lidocaine spray for topical pharyngeal anesthesia. Hemodynamic parameters before and after the procedure, including the heart rate (HR), mean arterial pressure (MAP), and pulse oxygen saturation (SPO 2) were recorded. Any adverse reactions experienced by the patient, including choking and respiratory depression, and the total dosage of propofol required during each procedure were also documented. RESULTS: Compared with pre-anesthetic data, the HR, MAP, and SPO2 were reduced after the completion of the painless gastroscopy procedure in both groups. However, the HR, MAP, and SPO2 measurements taken after the gastroscopy were significantly lower in the control group than those of the experimental group (P < 0.05); thus, the hemodynamic parameters of the experimental group were more stable. Compared with the control group, there was significant reduction in the total amount of propofol administered in the experimental group ( P < 0.05). The incidence of adverse reactions, including choking and respiratory depression, was significantly lower in the experimental group (P < 0.05). CONCLUSION: The results demonstrated that the application of topical pharyngeal anesthesia in painless gastroscopy can significantly reduce the incidence of adverse reactions. Thus, the combination of topical pharyngeal and intravenous anesthesia is worthy of clinical application and promotion.
资助项目	Scientific Research Project of Wenzhou Municipal Health Commission [Y2020295]
出版者	IOS PRESS
ISSN	0928-7329
EISSN	1878-7401
卷号	31 期号:4 页码:1245-1251
DOI	10.3233/THC-220516
页数	7
WOS类目	Health Care Sciences & Services ; Engineering, Biomedical
WOS研究方向	Health Care Sciences & Services ; Engineering
WOS记录号	WOS:001029075200011
收录类别	SCIE ; SCOPUS
URL	查看原文
PubMed ID	3684703
SCOPUSEID	2-s2.0-85164978861
通讯作者地址	[Yu, Yingcong]Department of Gastroenterology,The Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University,Wenzhou People's Hospital,No. 57 Canghou Street, Zhejiang,Wenzhou,325000,China ; [Song, Caiyun]Department of Gastroenterology,The Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University,Wenzhou People's Hospital,No. 57 Canghou Street, Zhejiang,Wenzhou,325000,China
Scopus学科分类	Biophysics;Bioengineering;Biomaterials;Information Systems;Biomedical Engineering;Health Informatics
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/182380
专题	其他_温州市第三临床学院（温州市人民医院）
通讯作者	Yu, Yingcong; Song, Caiyun
作者单位	Department of Gastroenterology,The Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University,Wenzhou People's Hospital,Wenzhou,China
第一作者单位	其他_温州市第三临床学院（温州市人民医院）
通讯作者单位	其他_温州市第三临床学院（温州市人民医院）
第一作者的第一单位	其他_温州市第三临床学院（温州市人民医院）
推荐引用方式 GB/T 7714	Lin, Xiaoxiao,Sun, Haoyue,Lin, Xizhou,et al. Application of topical pharyngeal anesthesia to reduce adverse reactions during painless gastroscopy: A prospective randomized study[J]. TECHNOLOGY AND HEALTH CARE,2023,31(4):1245-1251.
APA	Lin, Xiaoxiao., Sun, Haoyue., Lin, Xizhou., Liu, Ya., Hu, Sisi., ... & Song, Caiyun. (2023). Application of topical pharyngeal anesthesia to reduce adverse reactions during painless gastroscopy: A prospective randomized study. TECHNOLOGY AND HEALTH CARE, 31(4), 1245-1251.
MLA	Lin, Xiaoxiao,et al."Application of topical pharyngeal anesthesia to reduce adverse reactions during painless gastroscopy: A prospective randomized study".TECHNOLOGY AND HEALTH CARE 31.4(2023):1245-1251.