CT pelvimetry and clinicopathological parameters in evaluation of the technical difficulties in performing open rectal surgery for mid-low rectal cancer

doi:10.3892/ol.2015.3827

科研成果详情

题名	CT pelvimetry and clinicopathological parameters in evaluation of the technical difficulties in performing open rectal surgery for mid-low rectal cancer
作者	Zhou, Xiao-Cong1; Su, Meng 2; Hu, Ke-Qiong 3; Su, Yin-Fa 3; Ye, Ying-Hai1; Huang, Chong-Quan 4; Yu, Zhen-Lei 4; Li, Xiao-Yang 1; Zhou, Hong1; Ni, Yao-Zhong 1; Jiang, Yi 5; Lou, Zheng 6
发表日期	2016-01
发表期刊	ONCOLOGY LETTERS 影响因子和分区
语种	英语
原始文献类型	Article
关键词	computerized tomography rectal cancer pelvimetry clinicopathological parameters operative time intraoperative blood loss three-dimensional reconstruction
其他关键词	MESORECTAL EXCISION ; PREDICT ; RESECTABILITY ; RESECTION ; PELVIS
摘要	The present study aimed to evaluate the predictive value of pelvic anatomical and clinicopathological parameters for use in the estimation of the likely technical difficulties that may be encountered when performing open rectal surgery for mid-low rectal cancer. Sixty consecutive patients, undergoing open rectal surgery for mid-low rectal cancer were recruited between June 2009 and April 2014. All of the surgical procedures conducted, were low anterior resection (LAR) or abdominoperineal resection (APR). The operations were performed by the same surgeon and surgical team. Pelvic dimensions and angles were measured using three-dimensional reconstruction of spiral computerized tomography (CT) images. Operative time and intraoperative blood loss were used as indicators of operative difficulty. The independent variables were pelvic anatomical and clinicopathological parameters, and the dependent variables were operative time and intraoperative blood loss. Univariate and multivariate analyses were performed in order to determine the predictive significance of these variables. The pelvis width was significantly wider in females than in males (P<0.05), while the sacrococcygeal bending degree was significantly greater in males than in females (P<0.05). No significant difference were detected between the pelvis depth of females and males (P>0.05). Multivariate analyses showed that body mass index (BMI), tumor height, lymph node metastasis, anteroposterior diameter of the pelvic inlet, anteroposterior diameter of the pelvic outlet, height of the pubic symphysis, the sacrococcygeal distance, sacrococcygeal-pubic angle and diameter of the upper pubis to the coccyx were the main factors affecting the operative time (all P<0.05), while the maximum diameter of the tumor was the primary factor affecting intraoperative blood loss (P<0.05). Between the two procedures, the clinicopathological parameters appeared to be more valuable for predicting difficulty in LAR, in which operative time was associated with tumor height and tumor staging (R-C(2)=0.312; P<0.001). By contrast, the pelvic anatomical parameters appeared to be more valuable predictors of variation in APR, in which intraoperative blood loss was associated with the anteroposterior diameter of the mid-pelvis, the anteroposterior diameter of the pelvic outlet, the interspinous diameter, the depth of the sacral curvature and the sacropubic distance (R-C(2)=0.608; P=0.002). BMI, tumor height and the maximum diameter of the tumor may be used to predict the operative difficulty in performing open rectal surgery for mid-low rectal cancer. In addition to the associated clinicopathological parameters, wider, shallower and less curved pelvises may make the greatest contribution to reducing operative time and intraoperative blood loss. Operative difficulty is likely to be increased in deeper and narrower pelvises, or in those with greater sacrococcygeal curvature.
资助项目	Technology Planning Project of Wenzhou Science & Technology Bureau [Y20130383]
出版者	SPANDIDOS PUBL LTD
出版地	ATHENS
ISSN	1792-1074
EISSN	1792-1082
卷号	11 期号:1 页码:31-38
DOI	10.3892/ol.2015.3827
页数	8
WOS类目	Oncology
WOS研究方向	Oncology
WOS记录号	WOS:000367867200005
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	26870163
PMC记录号	PMC4727119
SCOPUSEID	2-s2.0-84948844417
通讯作者地址	[Zhou, Xiao-Cong]Department of Surgery,The Dingli Clinical Institute of Wenzhou Medical University,Wenzhou Central Hospital,32 Da Jian Lane,Wenzhou,325000,China
Scopus学科分类	Oncology;Cancer Research
引用统计	被引频次：23[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/18099
专题	温州医科大学附属第一医院
通讯作者	Zhou, Xiao-Cong
作者单位	1.Department of Surgery,The Dingli Clinical Institute of Wenzhou Medical University,Wenzhou Central Hospital,China; 2.Department of Radio-Chemotherapy Oncology,The First Affiliated Hospital of Wenzhou Medical University,China; 3.Departments of Clinical Pharmacy,The Dingli Clinical Institute ofWenzhou Medical University,Wenzhou Central Hospital,Wenzhou,325000,China; 4.Department of Radiology,The Dingli Clinical Institute of Wenzhou Medical University,Wenzhou Central Hospital,Wenzhou,325000,China; 5.Department of Pathology,The Dingli Clinical Institute of Wenzhou Medical University,Wenzhou Central Hospital,Wenzhou,325000,China; 6.Department of Colorectal Surgery,Changhai Hospital,Shanghai,200433,China
第一作者单位	温州医科大学
通讯作者单位	温州医科大学
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Zhou, Xiao-Cong,Su, Meng,Hu, Ke-Qiong,et al. CT pelvimetry and clinicopathological parameters in evaluation of the technical difficulties in performing open rectal surgery for mid-low rectal cancer[J]. ONCOLOGY LETTERS,2016,11(1):31-38.
APA	Zhou, Xiao-Cong., Su, Meng., Hu, Ke-Qiong., Su, Yin-Fa., Ye, Ying-Hai., ... & Lou, Zheng. (2016). CT pelvimetry and clinicopathological parameters in evaluation of the technical difficulties in performing open rectal surgery for mid-low rectal cancer. ONCOLOGY LETTERS, 11(1), 31-38.
MLA	Zhou, Xiao-Cong,et al."CT pelvimetry and clinicopathological parameters in evaluation of the technical difficulties in performing open rectal surgery for mid-low rectal cancer".ONCOLOGY LETTERS 11.1(2016):31-38.