Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients

doi:10.1186/s12866-023-02872-3

科研成果详情

题名	Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients
作者	Wei, Nana 1; Zhu, Guangqi2; Zhao, Tingxiao 3; Wang, Yan 2; Lou, Haifei 2; Li, Haoxuan 4; Yang, Zhejuan 2; Zhang, Zheen 2; Wang, Qiujing 2; Han, Mingfang 2; Lin, Zhibing 5; Li, Shibo2
发表日期	2023-05-09
发表期刊	BMC MICROBIOLOGY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	COVID-19 Oral bacteria Oral fungi Recovered patients Virus clearance
其他关键词	HEALTH
摘要	COVID-19 has emerged as a global pandemic, challenging the world's economic and health systems. Human oral microbiota comprises the second largest microbial community after the gut microbiota and is closely related to respiratory tract infections; however, oral microbiomes of patients who have recovered from COVID-19 have not yet been thoroughly studied. Herein, we compared the oral bacterial and fungal microbiota after clearance of SARS-CoV-2 in 23 COVID-19 recovered patients to those of 29 healthy individuals. Our results showed that both bacterial and fungal diversity were nearly normalized in recovered patients. The relative abundance of some specific bacteria and fungi, primarily opportunistic pathogens, decreased in recovered patients (RPs), while the abundance of butyrate-producing organisms increased in these patients. Moreover, these differences were still present for some organisms at 12 months after recovery, indicating the need for long-term monitoring of COVID-19 patients after virus clearance.
资助项目	Zhejiang province[2020C31001,2020C31003];National Natural Science Foundation of China[32270068];
出版者	BMC
ISSN	1471-2180
卷号	23 期号:1
DOI	10.1186/s12866-023-02872-3
页数	10
WOS类目	Microbiology
WOS研究方向	Microbiology
WOS记录号	WOS:000983972800001
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	37158877
SCOPUSEID	2-s2.0-85158998821
通讯作者地址	[Li, Shibo]Department of Infectious Disease,Zhoushan Hospital,Wenzhou Medical University,Zhoushan,316021,China ; [Lin, Zhibing]Shanghai Key Laboratory of Veterinary Biotechnology,School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai,200240,China
Scopus学科分类	Microbiology;Microbiology (medical)
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/180029
专题	其他_附属舟山医院（舟山医院）
通讯作者	Lin, Zhibing; Li, Shibo
作者单位	1.Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education,East China Normal University,Shanghai,200241,China; 2.Department of Infectious Disease,Zhoushan Hospital,Wenzhou Medical University,Zhoushan,316021,China; 3.Department of Infectious Disease,Zhejiang University Zhoushan Hospital,Zhoushan,316021,China; 4.Wenzhou-Kean University,Wenzhou,325060,China; 5.Shanghai Key Laboratory of Veterinary Biotechnology,School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai,200240,China
通讯作者单位	其他_附属舟山医院（舟山医院）
推荐引用方式 GB/T 7714	Wei, Nana,Zhu, Guangqi,Zhao, Tingxiao,et al. Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients[J]. BMC MICROBIOLOGY,2023,23(1).
APA	Wei, Nana., Zhu, Guangqi., Zhao, Tingxiao., Wang, Yan., Lou, Haifei., ... & Li, Shibo. (2023). Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients. BMC MICROBIOLOGY, 23(1).
MLA	Wei, Nana,et al."Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients".BMC MICROBIOLOGY 23.1(2023).