Status of 18F-PSMA-1007-PET/CT compared with multiparametric MRI in preoperative evaluation of prostate cancer

doi:10.1007/s00345-023-04345-8

科研成果详情

题名	Status of 18F-PSMA-1007-PET/CT compared with multiparametric MRI in preoperative evaluation of prostate cancer
作者	Tang, Yufan 4; Ji, Xiaowei2; Lin, Qi 1; Huang, Hang1; Zhu, Honghui1; Huang, Xixi1; xie, Hui1; Chen, Wei 1; Zhuang, Yuandi3
发表日期	2023-03-17
发表期刊	World journal of urology 影响因子和分区
语种	英语
原始文献类型	Journal Article
关键词	18F-1007-PSMA-PET/CT Preoperative evaluation Prostate cancer mpMRI
其他关键词	DEFINITION ; PET/CT
摘要	Treatment of primary prostate cancer extremely depends on preoperative stage. The role of 18F-1007-PSMA-PET/CT in preoperative staging has not been well defined. Our aim was to compare the diagnostic performance of 18F-1007-PEMA-PET/CT, mpMRI, and mpMRI + PEMA-PET/CT in local progression and lymph node invasion of prostate cancer using histopathology as the gold standard.}, {AbstractText=In this retrospective study, all patients with prostate cancer who underwent mpMRI and 18F-PSMA-1007-PET/CT before operation were included. The role of preoperative imaging was evaluated by predicting the sensitivity and specificity of EPE (extraprostatic extension), SVI (seminal vesicle invasion), and lymph node invasion results.}, Ultimately, 130 patients were included in this study. In the preoperative judgment of EPE and SVI, mpMRI + PSMA-PET/CT had higher sensitivity and specificity. When predicting lymph node metastasis, PSMA-PET/CT was the best choice. The accuracy of mpMRI + PSMA-PET/CT and PSMA-PET/CT in the T and N stages, respectively, was affected by the least factors., {AbstractText=Based on the combined results of mpMRI and 18F-1007-PSMA-PET/CT, the accuracy of the preoperative judgment of prostatic capsule invasion can be improved, which may be conducive to developing intra-fascial technology while ensuring no tumor-touch isolation. PSMA-PET/CT has the advantages over mpMRI alone in terms of lymph node positivity. Compared with PSMA-PET/CT alone, the combined results can improve the sensitivity, but reduce specificity. Therefore, it is recommended to focus on PSMA-PET/CT to decide whether lymph node dissection should be performed
资助项目	Zhejiang Provincial Natural Science Foundation of China [LQ20H050001, LY20H160013]
出版者	SPRINGER
ISSN	0724-4983
EISSN	1433-8726
卷号	41 期号:4 页码:1017-1024
DOI	10.1007/s00345-023-04345-8
页数	8
WOS类目	Urology & Nephrology
WOS研究方向	Urology & Nephrology
WOS记录号	WOS:000952171000002
收录类别	PUBMED ; SCIE ; SCOPUS
在线发表日期	2023-03
URL	查看原文
PubMed ID	36932282
SCOPUSEID	2-s2.0-85150053681
通讯作者地址	[xie, Hui]Department of Urology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China ; [Chen, Wei]Department of Urology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China ; [Zhuang, Yuandi]Department of Radiology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
Scopus学科分类	Urology
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/174359
专题	附属第一医院第一临床医学院（信息与工程学院）、附属第一医院_影像医学与核医学_放射科
通讯作者	xie, Hui; Chen, Wei; Zhuang, Yuandi
作者单位	1.Department of Urology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 2.Department of Nuclear Medicine,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 3.Department of Radiology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 4.Department of Urology,Jiashan County First People’s Hospital,Jiaxing,China
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
推荐引用方式 GB/T 7714	Tang, Yufan,Ji, Xiaowei,Lin, Qi,et al. Status of 18F-PSMA-1007-PET/CT compared with multiparametric MRI in preoperative evaluation of prostate cancer[J]. World journal of urology,2023,41(4):1017-1024.
APA	Tang, Yufan., Ji, Xiaowei., Lin, Qi., Huang, Hang., Zhu, Honghui., ... & Zhuang, Yuandi. (2023). Status of 18F-PSMA-1007-PET/CT compared with multiparametric MRI in preoperative evaluation of prostate cancer. World journal of urology, 41(4), 1017-1024.
MLA	Tang, Yufan,et al."Status of 18F-PSMA-1007-PET/CT compared with multiparametric MRI in preoperative evaluation of prostate cancer".World journal of urology 41.4(2023):1017-1024.