Engineering Advanced Drug Delivery Systems for Dry Eye: A Review

doi:10.3390/bioengineering10010053

科研成果详情

题名	Engineering Advanced Drug Delivery Systems for Dry Eye: A Review
作者	Wang, Tian-Zuo 1,2; Liu, Xin-Xin1,2; Wang, Si-Yu 1,3; Liu, Yan 1,3; Pan, Xin-Yang1,2; Wang, Jing-Jie1,2,3; Nan, Kai-Hui1,2,3
发表日期	2023-01
发表期刊	BIOENGINEERING-BASEL 影响因子和分区
语种	英语
原始文献类型	Review
关键词	dry eye disease drug delivery new dosage forms treatment
摘要	Dry eye disease (DED) is a widespread and frequently reported multifactorial ocular disease that not only causes ocular discomfort but also damages the cornea and conjunctiva. At present, topical administration is the most common treatment modality for DED. Due to the existence of multiple biological barriers, instilled drugs generally exhibit short action times and poor penetration on the ocular surface. To resolve these issues, several advanced drug delivery systems have been proposed. This review discusses new dosage forms of drugs for the treatment of DED in terms of their characteristics and advantages. Innovative formulations that are currently available in the market and under clinical investigation are elaborated. Meanwhile, their deficiencies are discussed. It is envisioned that the flourishing of advanced drug delivery systems will lead to improved management of DED in the near future.
资助项目	Major Science and Technology Program of Wenzhou City [ZS2017015]; School of Ophthalmology and Optometry, Wenzhou Medical University [J02-20190202, YNZD2201901]
出版者	MDPI
出版地	BASEL
ISSN	2306-5354
EISSN	2306-5354
卷号	10 期号:1
DOI	10.3390/bioengineering10010053
页数	16
WOS类目	Biotechnology & Applied Microbiology ; Engineering, Biomedical
WOS研究方向	Biotechnology & Applied Microbiology ; Engineering
WOS记录号	WOS:000916908500001
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	36671625
SCOPUSEID	2-s2.0-85146760745
通讯作者地址	[Wang, Jing-Jie]State Key Laboratory of Ophthalmology,Optometry and Vision Science,School of Ophthalmology & Optometry,Wenzhou Medical University,Wenzhou,325027,China ; [Nan, Kai-Hui]State Key Laboratory of Ophthalmology,Optometry and Vision Science,School of Ophthalmology & Optometry,Wenzhou Medical University,Wenzhou,325027,China
Scopus学科分类	Bioengineering
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/172090
专题	眼视光学院（生物医学工程学院）、附属眼视光医院仁济学院_眼视光、生物医学工程学部
通讯作者	Wang, Jing-Jie; Nan, Kai-Hui
作者单位	1.State Key Laboratory of Ophthalmology,Optometry and Vision Science,School of Ophthalmology & Optometry,Wenzhou Medical University,Wenzhou,325027,China; 2.National Clinical Research Center for Ocular Diseases,Wenzhou,325027,China; 3.National Engineering Research Center of Ophthalmology and Optometry,School of Biomedical Engineering,Wenzhou Medical University,Wenzhou,325027,China
第一作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
通讯作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
第一作者的第一单位	眼视光学院（生物医学工程学院）、附属眼视光医院
推荐引用方式 GB/T 7714	Wang, Tian-Zuo,Liu, Xin-Xin,Wang, Si-Yu,et al. Engineering Advanced Drug Delivery Systems for Dry Eye: A Review[J]. BIOENGINEERING-BASEL,2023,10(1).
APA	Wang, Tian-Zuo., Liu, Xin-Xin., Wang, Si-Yu., Liu, Yan., Pan, Xin-Yang., ... & Nan, Kai-Hui. (2023). Engineering Advanced Drug Delivery Systems for Dry Eye: A Review. BIOENGINEERING-BASEL, 10(1).
MLA	Wang, Tian-Zuo,et al."Engineering Advanced Drug Delivery Systems for Dry Eye: A Review".BIOENGINEERING-BASEL 10.1(2023).