Risk factors for rapid eye-movement sleep-related behavioral disorders (RBDs): A systematic review and a meta-analysis

doi:10.1016/j.genhosppsych.2022.10.009

科研成果详情

题名	Risk factors for rapid eye-movement sleep-related behavioral disorders (RBDs): A systematic review and a meta-analysis
作者	Wu, Zijing1; Wu, Junxin1; Xie, Caixia1; Wang, Luchun 2,3; Li, Huizi 2,3; Zhang, Ming 4; Fu, Zhiqiang 5; Lin, Yongsheng 5; Qian, Bing 5; Zhu, Limao 5; Yu, Xin 2,3; He, Jincai6; Qi, Wei 5; Wang, Huali 1,2,3
发表日期	2022
发表期刊	GENERAL HOSPITAL PSYCHIATRY 影响因子和分区
语种	英语
原始文献类型	Review
关键词	REM sleep behavior disorder risk factors meta -analysis
其他关键词	REM-SLEEP ; PARKINSONS-DISEASE ; COGNITIVE IMPAIRMENT ; META-REGRESSION ; QUESTIONNAIRE ; ANTIDEPRESSANTS ; HALLUCINATIONS ; DYSFUNCTION ; PROGRESSION ; FEATURES
摘要	Objective: The present study aimed to systematically analyze the risk factors for RBD. Methods: A systematic review and meta-analysis of case-control studies, cohort studies, and cross-sectional studies derived from the articles published in eight electronic databases before December 1, 2021. The primary outcome was the odds ratio (OR) and 95% confidence interval (95% CI), and heterogeneity was quantified using I2. Subgroup analyses and meta-regression were used to explore sources of heterogeneity. Egger's test and sensitivity analysis were performed. The PROSPERO ID number of the present study is CRD42021293942. Results: We identified 26 studies (44,230 subjects) among 2022 citations, and 13 factors were considered. Male sex (OR = 1.36, 95% CI = 1.13-1.64), smoking (OR = 1.37, 95% CI: 1.26-1.50), depression (OR = 2.06, 95% CI = 1.66-2.56), antidepressant use (OR = 2.36, 95% CI = 1.98-2.82), duration of neuropsychiatric disorders(OR = 1.43, 95% CI = 1.13-1.73), levodopa equivalent daily dose (LEDD, OR = 60.15, 95% CI = 23.95-96.35) and observable motor dysfunction (OR = 2.43, 95% CI = 0.65-4.22) were associated with a higher risk of RBD. Tertiary education and above (OR = 0.58, 95% CI = 0.35-0.96) was associated with a lower RBD risk. Men (OR = 1.40, 95% CI: 1.10-1.78, I2 = 0%, P = 0.005) and older individual (OR = 2.73, 95% CI: 1.03-4.43, I2 = 60%, P = 0.002) were more likely to have iRBD. Conclusion: Six modifiable risk factors and one protective factor were associated with RBD. Further research is required to understand the mechanisms and to develop preventative strategies.
资助项目	Science and Technology Innovation 2030- Major Project [2021ZD0201805]
出版者	ELSEVIER SCIENCE INC
出版地	NEW YORK
ISSN	0163-8343
EISSN	1873-7714
卷号	79 页码:118-127
DOI	10.1016/j.genhosppsych.2022.10.009
页数	10
WOS类目	Psychiatry
WOS研究方向	Psychiatry
WOS记录号	WOS:000884864000003
收录类别	SCIE ; SCOPUS ; PUBMED ; SSCI
URL	查看原文
PubMed ID	36375340
SCOPUSEID	2-s2.0-85140804771
社科自定义期刊分类	D类
通讯作者地址	[Wang, Huali]Dementia Care and Research Center,Peking University Institute of Mental Health,Beijing,100191,China ; [Qi, Wei]Shangrao Third Hospital,Shangrao,334000,China
Scopus学科分类	Psychiatry and Mental Health
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/171697
专题	精神医学学院第二临床医学院、附属第二医院、育英儿童医院_神经病学
通讯作者	Qi, Wei; Wang, Huali
作者单位	1.School of Mental Health,Wenzhou Medical University,Wenzhou,325000,China; 2.Dementia Care and Research Center,Beijing Dementia Key Lab,Peking University Institute of Mental Health (Sixth Hospital),Beijing,100191,China; 3.NHC Key Laboratory of Mental Health (Peking University),National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital),Beijing,100191,China; 4.Department of Psychiatry,The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou,510630,China; 5.Shangrao Third Hospital,Shangrao,334000,China; 6.Department of Neurology,First Hospital of Wenzhou Medical University,Wenzhou,325000,China
第一作者单位	精神医学学院
第一作者的第一单位	精神医学学院
推荐引用方式 GB/T 7714	Wu, Zijing,Wu, Junxin,Xie, Caixia,et al. Risk factors for rapid eye-movement sleep-related behavioral disorders (RBDs): A systematic review and a meta-analysis[J]. GENERAL HOSPITAL PSYCHIATRY,2022,79:118-127.
APA	Wu, Zijing., Wu, Junxin., Xie, Caixia., Wang, Luchun., Li, Huizi., ... & Wang, Huali. (2022). Risk factors for rapid eye-movement sleep-related behavioral disorders (RBDs): A systematic review and a meta-analysis. GENERAL HOSPITAL PSYCHIATRY, 79, 118-127.
MLA	Wu, Zijing,et al."Risk factors for rapid eye-movement sleep-related behavioral disorders (RBDs): A systematic review and a meta-analysis".GENERAL HOSPITAL PSYCHIATRY 79(2022):118-127.