The Use of the Angiosome Concept for Treating Infrapopliteal Critical Limb Ischemia through Interventional Therapy and Determining the Clinical Significance of Collateral Vessels

doi:10.1016/j.avsg.2015.09.021

科研成果详情

题名	The Use of the Angiosome Concept for Treating Infrapopliteal Critical Limb Ischemia through Interventional Therapy and Determining the Clinical Significance of Collateral Vessels
作者	Zheng, Xiang-Tao 1; Zeng, Rui-Chao 2; Huang, Jing-Yong1; Pan, Le-Men1; Su, Xiang1; Wu, Zi-Heng 3; Yu, Guan-Feng1
发表日期	2016-04
发表期刊	ANNALS OF VASCULAR SURGERY 影响因子和分区
语种	英语
原始文献类型	Article
其他关键词	REVASCULARIZATION ; OUTCOMES ; PREDICTORS
摘要	Background: The purpose of this study was to evaluate the clinical significance of the involvement of collateral vessels in interventional therapy based on the angiosome concept for infrapopliteal critical limb ischemia (CLI). Methods: We enrolled 486 patients with unilateral infrapopliteal CLI (Rutherford Stage 5 or 6) treated at 2 hospitals from January 2005 to December 2014. Using the angiosome concept, the patients were categorized into 3 groups: the direct revascularization (DR) group, the indirect revascularization through collaterals (IR-tc) group, and the indirect revascularization without collaterals (IR-wc) group. The data from 1 year of follow-up after the initial surgery were analyzed for all 3 groups. Results: During the 1-year follow-up, the unhealed ulcer rate of the IR-wc group was significantly higher than that of the DR group (83.4% vs. 31.7%, P < 0.001) and the IR-tc group (83.4% vs. 34.8%, P < 0.001). Furthermore, the limb salvage rate of the IR-wc group was significantly lower than that of the DR group (70.4% vs. 89.2%, P < 0.001) and the IR-tc group (70.4% vs. 85.4%, P = 0.0013). However, there were no differences in the unhealed ulcer rate or the limb salvage rate between the DR group and the IR-tc group (31.7% vs. 34.8%, P = 0.096 and 89.2% vs. 85.4%, P = 0.2834, respectively). In addition, within the IR-wc group, the unhealed ulcer rate of diabetic patients was higher than that of patients without diabetes (90.0% vs. 74.6%, P = 0.0116), but there was no difference in the limb salvage rate between diabetic and nondiabetic patients. No differences in the unhealed ulcer rate or the limb salvage rate were found between diabetic and nondiabetic patients in the other 2 groups. Conclusions: Following the angiosome model of perfusion for endovascular therapy, directly revascularizing the feeding artery and indirectly achieving revascularization through collaterals can effectively prompt the healing of ulcers and decrease the amputation rate in patients with infrapopliteal CLI. Collateral vessels play a crucial role in the treatment of ischemic foot.
资助项目	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81200233]; Science and Technology Bureau of Wenzhou City [Y20140147]
出版者	ELSEVIER SCIENCE INC
出版地	NEW YORK
ISSN	0890-5096
EISSN	1615-5947
卷号	32 页码:41-49
DOI	10.1016/j.avsg.2015.09.021
页数	9
WOS类目	Surgery ; Peripheral Vascular Disease
WOS研究方向	Surgery ; Cardiovascular System & Cardiology
WOS记录号	WOS:000372944000008
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
Pubmed记录号	26802295
Scopus记录号	2-s2.0-84961165315
通讯作者地址	[Wu, Zi-Heng]Department of Vascular Surgery,First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China
scopus学科分类	Surgery;Cardiology and Cardiovascular Medicine
引用统计	被引频次：24[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/17077
专题	附属第一医院_血管外科附属第一医院_肿瘤外科
通讯作者	Wu, Zi-Heng
作者单位	1.Department of Vascular Surgery,First Affiliated Hospital,Wenzhou Medical University,Nanbaixiang, Ouhai District, Wenzhou, Zhejiang,325015,China; 2.Department of Oncological Surgery,First Affiliated Hospital,Wenzhou Medical University,Wenzhou,310003,China; 3.Department of Vascular Surgery,First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China
第一作者单位	附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Zheng, Xiang-Tao,Zeng, Rui-Chao,Huang, Jing-Yong,et al. The Use of the Angiosome Concept for Treating Infrapopliteal Critical Limb Ischemia through Interventional Therapy and Determining the Clinical Significance of Collateral Vessels[J]. ANNALS OF VASCULAR SURGERY,2016,32:41-49.
APA	Zheng, Xiang-Tao., Zeng, Rui-Chao., Huang, Jing-Yong., Pan, Le-Men., Su, Xiang., ... & Yu, Guan-Feng. (2016). The Use of the Angiosome Concept for Treating Infrapopliteal Critical Limb Ischemia through Interventional Therapy and Determining the Clinical Significance of Collateral Vessels. ANNALS OF VASCULAR SURGERY, 32, 41-49.
MLA	Zheng, Xiang-Tao,et al."The Use of the Angiosome Concept for Treating Infrapopliteal Critical Limb Ischemia through Interventional Therapy and Determining the Clinical Significance of Collateral Vessels".ANNALS OF VASCULAR SURGERY 32(2016):41-49.