Clinical analysis of Pulmonary Cryptococcosis in non-HIV Patients in South China

科研成果详情

题名	Clinical analysis of Pulmonary Cryptococcosis in non-HIV Patients in South China
作者	Xiaona Xie; Mayun Chen; Yao Dan; Xiaomei Xu; Xueding Cai; Xiaoying Huang
发表日期	2014-11-07
会议录名称	2014年浙江省内科学学术年会青年医师论坛暨内科常见病规范化诊疗国家级学习班论文汇编影响因子和分区
语种	英语
原始文献类型	中国会议
摘要	Aims The aim of this study was to investigate the clinical characteristics of pulmonary cryptococcosis occurring in non-HIV patients,and to develop early diagnosis of pulmonary cryptococcosis in immunocompetent cases as well.Methods We retrospectively reviewed the clinical data of 41 non-HIV infected patients with pulmonary cryptococcosis who were admitted to the First Affiliated Hospital of Wenzhou Medical University from January 2006to April 2014.Results The study included a total of 41 patients(23 males and 18 females)with mean age of 47 years.12.19%of patients had a history of direct exposure to pigeon droppings;31.70%of the patients'working or living environments were potentially contaminated by fungal spores.Almost one-third of the patients involved into the study were asymptomatic.The most common clinical manifestations were cough,expectoration and hemoptysis.The most common radiological manifestation was single node or mass in lung,which was described as untypical.Of all cases,11 patients were diagnosed by CT-guided percutaneous cutting needle biopsy(PCNB),5 patients were diagnosed by operation,and Crytococcus spore was found in 7 patients'cerebrospinal fluid.8 patients'blood Cryptococcus Neoformans capsular polysaccharide antigens latex agglutination tests were positive.36 patients received antifungal therapy.5 patients underwent surgical resection.During 6 to 24 months follow-up,40 cases showed total recovery and 1cases showed improvement.Conclusions Pulmonary cryptococcosis in non-HIV subjects might be related to funguscontaminated environmental exposure.The great variations and protean manifestations of its clinical features often lead to misdiagnosis.Recognition and invasive examination of non-HIV infected patients'pulmonary cryptococcosis in the early stage may help with improvement of its diagnosis and prognosis.
页码	2
收录类别	CNKI
文献类型	会议论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/167893
专题	附属第一医院
作者单位	First Affiliated Hospital of Wenzhou Medical University Pulmonary Division
第一作者单位	附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Xiaona Xie,Mayun Chen,Yao Dan,et al. Clinical analysis of Pulmonary Cryptococcosis in non-HIV Patients in South China[C],2014:2.