Multiple primary malignancies-hepatocellular carcinoma combined with splenic lymphoma: A case report

科研成果详情

题名	Multiple primary malignancies-hepatocellular carcinoma combined with splenic lymphoma: A case report
作者	Fa-Zong Wu; Xiao-Xiao Chen; Wei-Yue Chen; Qiao-Hong Wu; Jian-Ting Mao; Zhong-Wei Zhao
发表日期	2022-10-06
发表期刊	World Journal of Clinical Cases 影响因子和分区
语种	英语
关键词	Multiple primary malignancies Hepatocellular carcinoma Splenomegaly Extra-hepatic primary malignancy Magnetic resonance imaging Primary non-Hodgkin'slymphoma Case report
摘要	BACKGROUND Primary liver cancer is one of the most common malignant tumours, while primary splenic lymphoma is a rare malignancy. Thus, cases of hepatocellular carcinoma(HCC) combined with splenic lymphoma are extremely rare.CASE SUMMARY We present a 62-year-old woman who was admitted to the Interventional Radiology Department with a lump in the spleen and liver as well as multiple enlarged lymph nodes visible by ultrasound. Contrast-enhanced computed of the abdomen revealed a circular, low-density, shallow mass(approximately 2.6 cm in diameter) in the left intrahepatic lobe and multiple round, low-density shadows in the spleen with clear boundaries(maximum diameter 7.6 cm). Based on the characteristic clinical symptoms and explicit radiological findings, the clinical diagnosis was HCC with metastasis to the liver portal, retroperitoneal lymph nodes, and spleen. After transcatheter arterial chemoembolization and sequential radiofrequency ablation, the-fetoprotein level returned to the normal range, and the hepatitis B cirrhosis improved. In addition, splenic tumour biopsy confirmed the diagnosis of primary malignant lymphoma, which went into remission after chemotherapy.CONCLUSION HCC with primary splenic non-Hodgkin lymphoma is extremely rare and easily misdiagnosed. Better understanding would facilitate early diagnosis, treatment and prognosis.
资助项目	Supported by the Medical and Health Technology Plan of Zhejiang Province;No. 2020KY1086 and No. 2022ZH086
卷号	10 期号:28 页码:10130-10135
收录类别	CNKI
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/167717
专题	其他_附属第五医院（丽水市中心医院）
作者单位	Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University
第一作者单位	温州医科大学
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Fa-Zong Wu,Xiao-Xiao Chen,Wei-Yue Chen,et al. Multiple primary malignancies-hepatocellular carcinoma combined with splenic lymphoma: A case report[J]. World Journal of Clinical Cases,2022,10(28):10130-10135.
APA	Fa-Zong Wu, Xiao-Xiao Chen, Wei-Yue Chen, Qiao-Hong Wu, Jian-Ting Mao, & Zhong-Wei Zhao. (2022). Multiple primary malignancies-hepatocellular carcinoma combined with splenic lymphoma: A case report. World Journal of Clinical Cases, 10(28), 10130-10135.
MLA	Fa-Zong Wu,et al."Multiple primary malignancies-hepatocellular carcinoma combined with splenic lymphoma: A case report".World Journal of Clinical Cases 10.28(2022):10130-10135.