Clinical features and treatment outcomes of eosinophilic gastroenteritis : an analysis of 28 cases

科研成果详情

题名	Clinical features and treatment outcomes of eosinophilic gastroenteritis : an analysis of 28 cases
作者	Yang, X. -M.1; He, S. -Q.1; Yang, H.3; Zheng, H. -H.4; Zhu, L. -H.2; Zhou, S. -K.5; Zhang, Y.1
发表日期	2019
发表期刊	ACTA GASTRO-ENTEROLOGICA BELGICA 影响因子和分区
语种	英语
原始文献类型	Article
摘要	Background : Eosinophilic gastroenteritis (EG) is uncommon disease, and the pathogenesis of this disease have yet to be fully clarified. Aim : This study was to describe the clinical manifestations, endoscopic features and treatment outcomes of a cohort of patients with EG. Method : This retrospective study was included 28 consecutive patients who were diagnosed EG between January 2011 and December 2015 in Taizhou Hospital. The patients' clinical manifestations, endoscopic features and treatment outcomes were reviewed from a prospectively maintained database. Results : Twenty-eight patients with EG were enrolled in the study (median age 54 years). The main symptoms were abdominal pain (78.6%), abdominal distension (50.0%), nausea and vomiting (28.6%) and diarrhea (25.0%). Laboratory examinations showed the elevation of blood eosinophil count (85.7%), serum IgE (71.4%). Endoscopic findings included small patchy mucosal erythema or erosions (75.0%), mucosal fold thickening (17.9%), submucosal nodules (21.4%), small gastroduodenal ulcers (14.3%). Twenty patients were treated and responded to prednisolone but five patients (25.0%) relapsed during the follow-up. The other 8 patients were treated with loratadine, proton pump inhibitors and dietary modification, 5 patients had clinical resolution during the follow-up. The other 3 patients did not achieve clinical remission, and then were given prednisone treatment. Conclusion : For some patients with gastrointestinal symptoms and peripheral eosinophilia, a high suspicion of EG is necessary and multiple endoscopic examinations might be helpful in diagnosis of EG. Most patients with EG could achieve remission after with the treatment of steroid or dietary elimination therapy.
资助项目	Science Technology Department of Zhejiang Province [2013C33112]; Science and Technology Bureau of Taizhou City [2013A33204]
出版者	UNIV CATHOLIQUE LOUVAIN-UCL
出版地	BRUSSELS
ISSN	1784-3227
卷号	82 期号:1 页码:5-10
页数	6
WOS类目	Gastroenterology & Hepatology
WOS研究方向	Gastroenterology & Hepatology
WOS记录号	WOS:000473740400002
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	30888747
SCOPUSEID	2-s2.0-85063298621
通讯作者地址	[Zhou, S. -K.]Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Dept Gastrointestinal Surg, 150 Ximen St, Linhai, Zhejiang, Peoples R China.
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/15843
专题	其他_附属台州医院（浙江省台州医院）附属台州医院基础医学院（机能实验教学中心）_病理学与病理生理学系_病理学
通讯作者	Zhou, S. -K.
作者单位	1.Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Dept Gastroenterol, 150 Ximen St, Linhai, Zhejiang, Peoples R China; 2.Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Dept Med Adm, Linhai, Peoples R China; 3.Enze Hosp, Wenzhou Med Coll, Dept Radiol, 1th Tongyang East Rd, Taizhou City, Zhejiang, Peoples R China; 4.Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Dept Pathol, 150 Ximen St, Linhai, Zhejiang, Peoples R China; 5.Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Dept Gastrointestinal Surg, 150 Ximen St, Linhai, Zhejiang, Peoples R China
第一作者单位	附属台州医院（浙江省台州医院）; 附属台州医院
通讯作者单位	附属台州医院（浙江省台州医院）; 附属台州医院
第一作者的第一单位	附属台州医院（浙江省台州医院）
推荐引用方式 GB/T 7714	Yang, X. -M.,He, S. -Q.,Yang, H.,et al. Clinical features and treatment outcomes of eosinophilic gastroenteritis : an analysis of 28 cases[J]. ACTA GASTRO-ENTEROLOGICA BELGICA,2019,82(1):5-10.
APA	Yang, X. -M.., He, S. -Q.., Yang, H.., Zheng, H. -H.., Zhu, L. -H.., ... & Zhang, Y.. (2019). Clinical features and treatment outcomes of eosinophilic gastroenteritis : an analysis of 28 cases. ACTA GASTRO-ENTEROLOGICA BELGICA, 82(1), 5-10.
MLA	Yang, X. -M.,et al."Clinical features and treatment outcomes of eosinophilic gastroenteritis : an analysis of 28 cases".ACTA GASTRO-ENTEROLOGICA BELGICA 82.1(2019):5-10.