Hypoalbuminemia, a novel prognostic factor for prediction of long-term outcomes in critically ill patients with septic shock

科研成果详情

题名	Hypoalbuminemia, a novel prognostic factor for prediction of long-term outcomes in critically ill patients with septic shock
作者	Qian, Song-Zan1; Jin, Duo 2; Chen, Zhi-Bo3; Ye, Yin-Cai4; Xiang, Wei-Wei 4; Ye, Lian-Min1; Pan, Jing-Ye1
发表日期	2019
发表期刊	INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Serum albumin septic shock long-term mortality
其他关键词	SERUM-ALBUMIN ; RISK-FACTOR ; FAILURE ; SEPSIS ; MORTALITY ; RESUSCITATION ; HEALTH ; COHORT ; FLUID ; SCORE
摘要	The aim of this study was to explore the cut-off value of serum albumin to predict short and long term mortality outcomes in patients with septic shock. We performed a retrospective clinical study which analyzed data from adults with septic shock, that were exacted from the Multiparameter Intelligent Monitoring in Intensive Care III (version 1.3) database. The 30-day, 90-day and 1-year mortality rates were compared in patients stratified according to their serum albumin levels. The study included 1034 patients. An optimal cut-off value for serum albumin of 2.45 g/dl was determined using the Youden index. Hypoalbuminemia was defined as an albumin level < 2.45 g/dl. The Kaplan-Meier survival curves showed that a low serum albumin level (< 2.45 g/dl) was associated with poorer survival outcomes. Multivariable Cox regression analysis further revealed that hypoalbuminemia was an independent predictor of short and long-term mortality (30-day mortality hazard ratio [HR]. 1.439, 95% confidence interval [CI]. 1.142, 1.814; 90-day mortality HR 1.448, 95% CI 1.168, 1.795; and 1-year mortality HR 1.389, 95% CI 1.134, 1.702). Serum albumin of 2.45 g/dl was an optimal cut-off value to define hypoalbuminemia and it predicted short and long-term outcomes in patients with septic shock.
出版者	E-CENTURY PUBLISHING CORP
出版地	MADISON
ISSN	1940-5901
卷号	12 期号:6 页码:7401-7409
页数	9
WOS类目	Medicine, Research & Experimental
WOS研究方向	Research & Experimental Medicine
WOS记录号	WOS:000473289500097
收录类别	SCIE
通讯作者地址	[Pan, Jing-Ye]Wenzhou Med Univ, Affiliated Hosp 1, Dept Intens Care Unit, Wenzhou 325000, Peoples R China.
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/1573
专题	附属第一医院_重症医学科（ICU）第一临床医学院（信息与工程学院）、附属第一医院附属第一医院_输血科第一临床医学院（信息与工程学院）、附属第一医院_内科学_神经内科
通讯作者	Pan, Jing-Ye
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 1, Dept Intens Care Unit, Wenzhou 325000, Peoples R China; 2.Wenzhou Med Univ, Sch Clin Med Sci 1, Wenzhou 325000, Peoples R China; 3.Wenzhou Med Univ, Dept Neurol, Affiliated Hosp 1, Wenzhou 325000, Peoples R China; 4.Wenzhou Med Univ, Dept Blood Transfus Serv, Affiliated Hosp 1, Wenzhou 325000, Peoples R China
第一作者单位	附属第一医院; 重症医学科（ICU）
通讯作者单位	附属第一医院; 重症医学科（ICU）
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Qian, Song-Zan,Jin, Duo,Chen, Zhi-Bo,et al. Hypoalbuminemia, a novel prognostic factor for prediction of long-term outcomes in critically ill patients with septic shock[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2019,12(6):7401-7409.
APA	Qian, Song-Zan., Jin, Duo., Chen, Zhi-Bo., Ye, Yin-Cai., Xiang, Wei-Wei., ... & Pan, Jing-Ye. (2019). Hypoalbuminemia, a novel prognostic factor for prediction of long-term outcomes in critically ill patients with septic shock. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 12(6), 7401-7409.
MLA	Qian, Song-Zan,et al."Hypoalbuminemia, a novel prognostic factor for prediction of long-term outcomes in critically ill patients with septic shock".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 12.6(2019):7401-7409.