Risk Factors and Prognostic Analysis of Gastrointestinal Stromal Tumor Recurrence-Metastasis

doi:10.1155/2022/1127146

科研成果详情

题名	Risk Factors and Prognostic Analysis of Gastrointestinal Stromal Tumor Recurrence-Metastasis
作者	Chen, Shan1; Sang, Kanru 1; Chen, Wenjing 2; Jin, Jinji 2; Chen, Xiaolei 2; Zhu, Guanbao2; Wang, Pengfei2; Cai, Yiqi2
发表日期	2022-07-18
发表期刊	Computational and Mathematical Methods in Medicine 影响因子和分区
语种	英语
原始文献类型	Journal article (JA)
关键词	Diagnosis Multivariant analysis Nomograms Pathology Risk analysis Risk assessment Surgery Clinical data Cox analysis Digestive tract Factors analysis Gastrointestinal stromal tumors Prognostic analysis Risk factors Tumor recurrences Univariate Wenzhou
其他关键词	DIAGNOSIS ; BIOLOGY ; KIT
摘要	Objective. Gastrointestinal stromal tumors (GISTs) are potential malignancies that occur in the digestive tract. This study aimed to investigate the risk factors and prognosis of recurrence and metastasis of gastrointestinal stromal tumor (GIST). Methods. From January 2018 to December 2019, 422 patients with GIST who received surgery in the First Affiliated Hospital of Wenzhou Medical University were enrolled. Their clinical data were retrospectively analyzed, and their follow-ups were continued until March 31, 2022. Subsequently, univariate and multivariate Cox analyses, survival curves, and nomograms were adopted to explore the relationship between clinicopathological characteristics and recurrence or metastasis in patients with GIST. Results. Univariate and multivariate Cox analysis exhibited that the prognosis of patients was affected by tumor rupture (P=0.040), tumor location (P10 cm, high-risk tumor classification, and mitotic figures ≥10 per 50 HPFs. And the application of nomogram may help physicians provide individualized diagnosis and treatment for patients with GISTs following surgical resection. © 2022 Shan Chen et al.
资助项目	Department of Health of Zhejiang Province, China [Y2100660, 2016DTA006]; Zhejiang Provincial Health Department Medical Support Discipline-Nutrition [11-ZC24]; Wenzhou Municipal Science and Bureau [Y2020732]; Wenzhou Municipal Science and Technology Bureau [Y20170104]; National Innovation and Entrepreneurship Training Program for College Students [202110343022]
出版者	Hindawi Limited
出版地	LONDON
ISSN	1748-670X
EISSN	1748-6718
卷号	2022 页码:1127146
DOI	10.1155/2022/1127146
页数	10
WOS类目	Mathematical & Computational Biology
WOS研究方向	Mathematical & Computational Biology
WOS记录号	WOS:000853263000002
收录类别	EI ; PUBMED ; SCIE ; SCOPUS
EI入藏号	20223212537829
EI主题词	Tumors
EI分类号	461.2 Biological Materials and Tissue Engineering ; 461.6 Medicine and Pharmacology ; 914.1 Accidents and Accident Prevention ; 921.4 Combinatorial Mathematics, Includes Graph Theory, Set Theory ; 922 Statistical Methods
URL	查看原文
PubMed ID	35898476
SCOPUSEID	2-s2.0-85135203201
Scopus学科分类	Modeling and Simulation;Biochemistry, Genetics and Molecular Biology (all);Immunology and Microbiology (all);Applied Mathematics
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/153474
专题	第一临床医学院（信息与工程学院）、附属第一医院附属第一医院_胃肠外科
作者单位	1.First Clinical College of Wenzhou Medical University,Wenzhou,China; 2.Department of Gastrointestinal Surgery,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
第一作者单位	第一临床医学院（信息与工程学院）、附属第一医院
第一作者的第一单位	第一临床医学院（信息与工程学院）、附属第一医院
推荐引用方式 GB/T 7714	Chen, Shan,Sang, Kanru,Chen, Wenjing,et al. Risk Factors and Prognostic Analysis of Gastrointestinal Stromal Tumor Recurrence-Metastasis[J]. Computational and Mathematical Methods in Medicine,2022,2022:1127146.
APA	Chen, Shan., Sang, Kanru., Chen, Wenjing., Jin, Jinji., Chen, Xiaolei., ... & Cai, Yiqi. (2022). Risk Factors and Prognostic Analysis of Gastrointestinal Stromal Tumor Recurrence-Metastasis. Computational and Mathematical Methods in Medicine, 2022, 1127146.
MLA	Chen, Shan,et al."Risk Factors and Prognostic Analysis of Gastrointestinal Stromal Tumor Recurrence-Metastasis".Computational and Mathematical Methods in Medicine 2022(2022):1127146.