题名 | Nonhuman primate models of ischemic stroke and neurological evaluation after stroke |
作者 | |
发表日期 | 2022-07-01 |
发表期刊 | JOURNAL OF NEUROSCIENCE METHODS 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Article |
关键词 | Nonhuman primates Ischemia stroke MCAO Neurological evaluation |
其他关键词 | MIDDLE CEREBRAL-ARTERY ; THROMBOEMBOLIC STROKE ; BLOOD-FLOW ; THROMBOTIC STROKE ; FUNCTIONAL MRI ; INFARCT VOLUME ; MONKEY MODEL ; FOCAL STROKE ; OCCLUSION ; TRANSIENT |
摘要 | Nonhuman primates are closer to human beings than rodents in genetics, neuroanatomy, physiology and immunology. Nonhuman primates are therefore considered an ideal preclinical model to replicate various aspects of human stroke. Ischemia stroke models in nonhuman primates can better fit the physiological symptoms and changes in humans after cerebral ischemia. Currently, various construction methods and neurological evaluation methods have been developed and applied to stroke models of nonhuman primates, including craniectomy models, endovascular stroke models, autologous thrombus models and intraluminal filament models. Meanwhile, new innovative methods have emerged, such as the endothelin-1 model and photothrombosis model. In the past thirty years, these model studies have explored various mechanisms that are initiated in the first minutes, hours, and days after a stroke. Permanent and temporary middle cerebral artery occlusion models have been trying to simulate the complex situation of human stroke. However, a comprehensive comparison of the above methods, including their advantages and disadvantages, difficulty and application fields, is limited. Here, we introduce various modeling methods that are currently available for nonhuman primate stroke models, compare the differences between these different preparation methods, and analyze the advantages and disadvantages of the various methods and the fields of application. The imaging detection methods of nonhuman primates after cerebral ischemia and the neurological evaluation methods after stroke are also discussed briefly. Methods are sorted and compared so that scholars can choose appropriate modeling methods and evaluation methods to establish nonhuman primate stroke models. |
资助项目 | National Natural Sci-ence Foundation of China [81820108011, 81771262]; Zhejiang Provincial Natural Science Foundation [2020C03022, 2017C03027] |
出版者 | ELSEVIER |
出版地 | AMSTERDAM |
ISSN | 0165-0270 |
EISSN | 1872-678X |
卷号 | 376页码:109611 |
DOI | 10.1016/j.jneumeth.2022.109611 |
页数 | 12 |
WOS类目 | Biochemical Research Methods ; Neurosciences |
WOS研究方向 | Biochemistry & Molecular Biology ; Neurosciences & Neurology |
WOS记录号 | WOS:000798569000001 |
收录类别 | SCIE ; SCOPUS ; PUBMED |
URL | 查看原文 |
PubMed ID | 35487315 |
SCOPUSEID | 2-s2.0-85129734318 |
通讯作者地址 | [Zhuge, Qichuan]Department of Neurosurgery,First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China |
Scopus学科分类 | Neuroscience (all) |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/148725 |
专题 | 附属第一医院_神经外科 第一临床医学院(信息与工程学院)、附属第一医院_老化与神经疾病重点实验室 |
通讯作者 | Zhuge, Qichuan |
作者单位 | 1.Department of Neurosurgery,First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 2.Zhejiang Provincial Key Laboratory of Aging and Neurological Disorder Research,Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 3.Department of Neurology,Guangzhou First People's Hospital,Guangzhou,510000,China; 4.University of North Texas Health Science Center,Fort Worth,76107,United States |
第一作者单位 | 附属第一医院; 温州医科大学 |
通讯作者单位 | 附属第一医院 |
第一作者的第一单位 | 附属第一医院 |
推荐引用方式 GB/T 7714 | Lin, Xiao,Wang, Hua,Chen, Jiayu,et al. Nonhuman primate models of ischemic stroke and neurological evaluation after stroke[J]. JOURNAL OF NEUROSCIENCE METHODS,2022,376:109611. |
APA | Lin, Xiao., Wang, Hua., Chen, Jiayu., Zhao, Peiqi., Wen, Min., ... & Yang, Su. (2022). Nonhuman primate models of ischemic stroke and neurological evaluation after stroke. JOURNAL OF NEUROSCIENCE METHODS, 376, 109611. |
MLA | Lin, Xiao,et al."Nonhuman primate models of ischemic stroke and neurological evaluation after stroke".JOURNAL OF NEUROSCIENCE METHODS 376(2022):109611. |
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