Can long-term regular physical activity improve health outcomes among adults with asthma-evidence from a systematic review and Bayesian meta-analysis

doi:10.21037/atm-22-1170

科研成果详情

题名	Can long-term regular physical activity improve health outcomes among adults with asthma-evidence from a systematic review and Bayesian meta-analysis
作者	Shi, Shengqiao1,2; Huang, Hui1,2; Zheng, Rui1,2; Zhang, Ningjie1,2; Dai, Wei3; Liang, Jinghong 4; Dai, Yuanrong1,2
发表日期	2022-03
发表期刊	ANNALS OF TRANSLATIONAL MEDICINE 影响因子和分区
语种	英语
原始文献类型	Review
关键词	Asthma physical activity (PA) adults Bayesian meta-analysis
其他关键词	QUALITY-OF-LIFE ; OBESE ADULTS ; ADVERSE EVENTS ; WEIGHT-LOSS ; EXERCISE ; MODERATE ; RISK ; INFLAMMATION ; PROGRAM ; MANAGEMENT
摘要	Background: Evidence on the effects of regular physical activity (PA) on asthmatic adults is rather weak and inconsistent since previous studies were conducted based on the limited studies, various populations groups and single outcome. A systematic review (SR) and meta-analysis have a high level of evidence to comprehensively evaluate the effects of PA for adults with asthma based on the available data. Our study aims to provide an SR of available evidence regarding the effect of regular PA on asthma in adults. Methods: A comprehensive search strategy was conducted using the PubMed, EMBASE, Cochrane Library, and Web of Science databases from their inception to October 2021. We identifying the eligible studies based on the PIOS principles, namely, populations (adults with asthma), interventions (regular PA), outcomes (quality of life or relapse-related outcomes), study design [randomized controlled trials (RCTs)]. A Bayesian-based meta-analysis was performed to pool available evidence. Quality assessment for individual studies was performed with the Cochrane risk of bias tool and the Newcastle-Ottawa Scale (NOS). Results: A total of 22 publications (18 RCTs and 4 longitudinal studies) were identified, comprised of 85,392 individuals aged between 18 and 75 years old. Overall quality of the included studies was rated as low-to-moderated quality. We found that PA was effective in improving quality of life (QOL) [health related quality of life, (HRQoL) & Asthma Control Questionnaire, (ACQ): standard mean difference (SMD) =-0.80, 95% credible interval (CrI): -1.30 to -0.31; I2=86.9%, Pheterogeneity<0.001], pulmonary function (FEV1/pred) [weighted mean difference (MD) =0.47, 95% CrI: 0.03 to 0.90; I2=74.9%, Pheterogeneity<0.001], and maximal oxygen consumption (VO2max) (MD =1.18, 95% CrI: 0.87 to 1.48; I2=17.0%, Pheterogeneity=0.31). Based on the longitudinal studies, the long-term high-level PA group had a lower risk of developing asthma compared with the low-level PA group [odds ratio (OR) =0.87, 95% CrI: 0.78 to 0.95; I2=27.4%, Pheterogeneity=0.22)]. Discussion: Adults with asthma need to carried out regular PA in accordance with the recommendations, which will improve their QOL and pulmonary function, and moreover, long-term PA appears to be more beneficial for asthmatic patients. The quality and quantity of included studies might affect the interpretation.
出版者	AME PUBL CO
出版地	SHATIN
ISSN	2305-5839
EISSN	2305-5847
卷号	10 期号:6 页码:338
DOI	10.21037/atm-22-1170
页数	27
WOS类目	Oncology ; Medicine, Research & Experimental
WOS研究方向	Oncology ; Research & Experimental Medicine
WOS记录号	WOS:000778616900001
收录类别	SCIE ; PUBMED
URL	查看原文
PubMed ID	35434043
通讯作者地址	[Dai, Yuanrong]Wenzhou Med Univ, Affiliated Hosp 2, Dept Resp Med, Wenzhou 325000, Peoples R China. ; [Dai, Yuanrong]Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325000, Peoples R China. ; [Liang, Jinghong]Sun Yat Sen Univ, Sch Publ Hlth, Dept Maternal & Child Hlth, 74 Zhongshan 2nd Rd, Guangzhou 510080, Peoples R China.
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/148536
专题	附属第二医院_呼吸内科附属第二医院_神经内科第二临床医学院，附属第二医院、育英儿童医院
通讯作者	Liang, Jinghong; Dai, Yuanrong
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 2, Dept Resp Med, Wenzhou 325000, Peoples R China; 2.Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325000, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 2, Dept Neurol Rehabil, Wenzhou, Peoples R China; 4.Sun Yat Sen Univ, Sch Publ Hlth, Dept Maternal & Child Hlth, 74 Zhongshan 2nd Rd, Guangzhou 510080, Peoples R China
第一作者单位	附属第二医院_呼吸内科; 第二临床医学院，附属第二医院、育英儿童医院
通讯作者单位	附属第二医院_呼吸内科; 第二临床医学院，附属第二医院、育英儿童医院
第一作者的第一单位	附属第二医院_呼吸内科
推荐引用方式 GB/T 7714	Shi, Shengqiao,Huang, Hui,Zheng, Rui,et al. Can long-term regular physical activity improve health outcomes among adults with asthma-evidence from a systematic review and Bayesian meta-analysis[J]. ANNALS OF TRANSLATIONAL MEDICINE,2022,10(6):338.
APA	Shi, Shengqiao., Huang, Hui., Zheng, Rui., Zhang, Ningjie., Dai, Wei., ... & Dai, Yuanrong. (2022). Can long-term regular physical activity improve health outcomes among adults with asthma-evidence from a systematic review and Bayesian meta-analysis. ANNALS OF TRANSLATIONAL MEDICINE, 10(6), 338.
MLA	Shi, Shengqiao,et al."Can long-term regular physical activity improve health outcomes among adults with asthma-evidence from a systematic review and Bayesian meta-analysis".ANNALS OF TRANSLATIONAL MEDICINE 10.6(2022):338.