Expression and Regulation of Aquaporins in Pregnancy Complications and Reproductive Dysfunctions

doi:10.1089/dna.2020.5983

科研成果详情

题名	Expression and Regulation of Aquaporins in Pregnancy Complications and Reproductive Dysfunctions
作者	Shao, Hailing; Gao, Shichu; Ying, Xinxin; Zhu, Xueqiong; Hua, Ying
发表日期	2021
发表期刊	DNA AND CELL BIOLOGY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	aquaporin pregnancy complications expression regulation
其他关键词	CYCLIC ADENOSINE-MONOPHOSPHATE ; AMNIOTIC-FLUID VOLUME ; FETAL MEMBRANES ; WATER PERMEABILITY ; CHORIOAMNIOTIC MEMBRANES ; OVARIAN HYPERSTIMULATION ; REDUCED EXPRESSION ; TERM PREGNANCIES ; GENE-EXPRESSION ; MOUSE OOCYTES
摘要	Aquaporins (AQPs), small hydrophobic integral membrane proteins, mediate rapid transport of water and small solutes. The abnormal expressions of AQPs are associated with pregnancy complications and reproductive dysfunctions, including preeclampsia, gestational diabetes mellitus, tubal ectopic pregnancy, intrahepatic cholestasis of pregnancy, preterm birth, chorioamnionitis, polyhydramnios, and oligohydramnios, thus resulting in adverse pregnancy outcomes. This review explains the alterations of AQPs in pregnancy complications and reproductive dysfunctions and summarizes the molecular mechanisms involved in the regulations of AQPs by drugs such as oxytocin, polychlorinated biphenyls, all-trans-retinoic acid, salvia miltiorrhiza, and insulin, or other factors such as oxygen and osmotic pressure. All the researches provide evidence that AQPs could be the new therapeutic targets of pregnancy-related diseases.
资助项目	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81601319, 18331201]
出版者	MARY ANN LIEBERT, INC
出版地	NEW ROCHELLE
ISSN	1044-5498
EISSN	1557-7430
卷号	40 期号:1 页码:116-125
DOI	10.1089/dna.2020.5983
页数	10
WOS类目	Biochemistry & Molecular Biology ; Cell Biology ; Genetics & Heredity
WOS研究方向	Biochemistry & Molecular Biology ; Cell Biology ; Genetics & Heredity
WOS记录号	WOS:000592475700001
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	33226842
SCOPUSEID	2-s2.0-85099845626
通讯作者地址	[Zhu, Xueqiong]Department of Obstetrics and Gynecology,Second Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
Scopus学科分类	Molecular Biology;Genetics;Cell Biology
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/14108
专题	第二临床医学院，附属第二医院、育英儿童医院附属第二医院
通讯作者	Zhu, Xueqiong
作者单位	Department of Obstetrics and Gynecology,Second Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
第一作者单位	第二临床医学院，附属第二医院、育英儿童医院; 附属第二医院
通讯作者单位	第二临床医学院，附属第二医院、育英儿童医院; 附属第二医院
第一作者的第一单位	第二临床医学院，附属第二医院、育英儿童医院; 附属第二医院
推荐引用方式 GB/T 7714	Shao, Hailing,Gao, Shichu,Ying, Xinxin,et al. Expression and Regulation of Aquaporins in Pregnancy Complications and Reproductive Dysfunctions[J]. DNA AND CELL BIOLOGY,2021,40(1):116-125.
APA	Shao, Hailing, Gao, Shichu, Ying, Xinxin, Zhu, Xueqiong, & Hua, Ying. (2021). Expression and Regulation of Aquaporins in Pregnancy Complications and Reproductive Dysfunctions. DNA AND CELL BIOLOGY, 40(1), 116-125.
MLA	Shao, Hailing,et al."Expression and Regulation of Aquaporins in Pregnancy Complications and Reproductive Dysfunctions".DNA AND CELL BIOLOGY 40.1(2021):116-125.