N,N-dimethylformamide-induced acute hepatic failure: A case report and literature review

doi:10.3892/etm.2017.5213

科研成果详情

题名	N,N-dimethylformamide-induced acute hepatic failure: A case report and literature review
作者	Lei, Yuanli; Xiao, Shasha; Chen, Shouquan; Zhang, Haiyan; Li, Huiping; Lu, Yingru
发表日期	2017-12
发表期刊	EXPERIMENTAL AND THERAPEUTIC MEDICINE 影响因子和分区
语种	英语
原始文献类型	Review
关键词	acute hepatic failure N,N-dimethylformamide artificial liver support system case report abdominal computed tomography scan
其他关键词	LIVER SUPPORT-SYSTEM ; OCCUPATIONAL-EXPOSURE ; N-DIMETHYLFORMAMIDE
摘要	N,N-dimethylformamide (DMF) is a major solvent predominantly used in the chemical industry. The main toxic effects following exposure to DMF are gastric irritation, skin eruption and hepatotoxicity. However, hepatic failure induced by DMF is rare. In this report, we present a case of acute hepatic failure following exposure to a toxic dose of DMF via respiratory tract inhalation and skin absorption with detailed abdominal computed tomography scan, sequential laboratory data and polymorphisms. The patient recovered satisfactorily following artificial liver support therapy and pharmacological agents to protect the liver in addition to plasma, blood platelet and albumin transfusions. In view of the high mortality rate and rare occurrence rate of acute hepatic failure, the clinical characteristics, polymorphisms and therapeutic strategy of DMF poisoning are discussed.
出版者	SPANDIDOS PUBL LTD
出版地	ATHENS
ISSN	1792-0981
EISSN	1792-1015
卷号	14 期号:6 页码:5659-5663
DOI	10.3892/etm.2017.5213
页数	5
WOS类目	Medicine, Research & Experimental
WOS研究方向	Research & Experimental Medicine
WOS记录号	WOS:000417815000061
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	29285107
PMC记录号	PMC5740717
SCOPUSEID	2-s2.0-85032566128
通讯作者地址	[Lu, Yingru]Department of Emergency Medicine,The First Affiliated Hospital of Wenzhou Medical University,2 Fuxue Road,Wenzhou,325000,China
Scopus学科分类	Immunology and Microbiology (miscellaneous);Cancer Research
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/14010
专题	第一临床医学院（信息与工程学院）、附属第一医院_急诊医学附属第一医院
通讯作者	Lu, Yingru
作者单位	Department of Emergency Medicine,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,325000,China
第一作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院; 急诊医学
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院; 急诊医学
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Lei, Yuanli,Xiao, Shasha,Chen, Shouquan,et al. N,N-dimethylformamide-induced acute hepatic failure: A case report and literature review[J]. EXPERIMENTAL AND THERAPEUTIC MEDICINE,2017,14(6):5659-5663.
APA	Lei, Yuanli, Xiao, Shasha, Chen, Shouquan, Zhang, Haiyan, Li, Huiping, & Lu, Yingru. (2017). N,N-dimethylformamide-induced acute hepatic failure: A case report and literature review. EXPERIMENTAL AND THERAPEUTIC MEDICINE, 14(6), 5659-5663.
MLA	Lei, Yuanli,et al."N,N-dimethylformamide-induced acute hepatic failure: A case report and literature review".EXPERIMENTAL AND THERAPEUTIC MEDICINE 14.6(2017):5659-5663.