A novel ophthalmic viscosurgical device-free phakic intraocular lens implantation makes myopic surgery safer

doi:10.1186/s40662-020-00185-4

科研成果详情

题名	A novel ophthalmic viscosurgical device-free phakic intraocular lens implantation makes myopic surgery safer
作者	Pan, An-Peng; Wen, Li-Jin; Shao, Xu; Zhou, Kai-Jing; Wang, Qin-Mei; Qu, Jia; Yu, A-Yong
发表日期	2020-04-07
发表期刊	EYE AND VISION 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Phakic intraocular lens implantation Ophthalmic viscosurgical device-free Intraocular pressure Complications
其他关键词	CENTRAL HOLE ; FOLLOW-UP ; CLINICAL-OUTCOMES ; MODERATE ; PRESSURE ; HYDROIMPLANTATION ; PREVALENCE
摘要	Purpose To assess the efficacy and safety of a novel ophthalmic viscosurgical device-free (OVD-free) method for posterior chamber phakic intraocular lens (PIOL) implantation in myopic eyes. Methods In this retrospective cohort study, the medical records of myopic eyes that underwent PIOL (Implantable Collamer Lens, ICL) implantation for myopia correction at the Eye Hospital of Wenzhou Medical University between May 2015 and March 2017 were reviewed. A total of 49 eyes with complete data that met follow up requirements (2 h, 1 day, 1 week, 3 months postoperatively) were recruited. Based on the surgical techniques used, the eyes were divided into the OVD-free method group and the standard method group. The clinical data, including intraocular pressure (IOP), corrected distance visual acuity (CDVA) and spherical equivalent (SE), at each follow-up were collected for comparison. Endothelial cell loss and complications were also investigated. Results Twenty-one eyes received the standard method, and 28 eyes received the OVD-free method. A rise in IOP > 22 mmHg at 2 h was noted in 14 eyes (66.7%) in the standard group and none (0%) in the OVD-free group (p < 0.001). The rise in IOP from baseline was significantly higher at 2 h in the standard group (10.5 +/- 5.2 mmHg vs. 2.2 +/- 3.3 mmHg, difference: 8.3, 95% CI 5.8 to 10.8; p < 0.001). There was a significant difference in the time course of LogMAR CDVA changes between the two groups (p = 0.047). The LogMAR CDVA was significantly better in the OVD-free method group compared to the standard group at 1 day (- 0.076, 95% CI - 0.134 to - 0.018; p = 0.012), 1 week (- 0.071, 95% CI - 0.135 to - 0.007; p = 0.03), but not at 3 months (- 0.046, 95% CI - 0.107 to 0.015; p = 0.134). There was no significant difference in the time course of SE changes between the two groups (p = 0.471; p = 0.705). In the OVD-free group, mean endothelial cell loss was 4.6% at 3 months (2522 +/- 281 vs. 2407 +/- 226 cells/mm(2), difference: -115, 95% CI - 295 to 65; p = 0.187). No complications were reported in both groups except for the early IOP elevation in the standard group during the observation period. Conclusions The OVD-free method is safe and efficient for ICL implantation. It can be a safer method of ICL implantation compared to the standard method in that it completely eliminates ophthalmic viscoelastic devices-related complications without causing additional complications.
资助项目	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81570869]; Zhejiang Provincial Natural Science Foundation of ChinaNatural Science Foundation of Zhejiang Province [Y2110784]; Zhejiang Provincial Foundation of China for Distinguished Young Talents in Medicine and Health [2010QNA018]; Wenzhou Key Team of Scientific and Technological Innovation [C20170002]; Foundation of Wenzhou City Science & Technology Bureau [Y20140705]; Engineering Development Project of Ophthalmology and Optometry [GCKF201601]
出版者	BMC
出版地	LONDON
ISSN	2326-0254
卷号	7 期号:1 页码:18
DOI	10.1186/s40662-020-00185-4
页数	9
WOS类目	Ophthalmology
WOS研究方向	Ophthalmology
WOS记录号	WOS:000525257200001
收录类别	SCIE ; PUBMED ; CSCD ; SCOPUS
学科领域	医药、卫生
URL	查看原文
CSCD记录号	CSCD:6927074
PubMed ID	32280722
PMC记录号	PMC7137322
SCOPUSEID	2-s2.0-85100460676
通讯作者地址	[Yu, A-Yong]The Eye Hospital of Wenzhou Medical University,270 Xueyuan West Road, Zhejiang,Wenzhou,325000,China
Scopus学科分类	Health Professions (miscellaneous);Ophthalmology
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/1382
专题	眼视光学院（生物医学工程学院）、附属眼视光医院眼视光学院（生物医学工程学院）、附属眼视光医院_白内障中心
通讯作者	Yu, A-Yong
作者单位	The Eye Hospital of Wenzhou Medical University,270 Xueyuan West Road, Zhejiang,Wenzhou,325000,China
第一作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
通讯作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
第一作者的第一单位	眼视光学院（生物医学工程学院）、附属眼视光医院
推荐引用方式 GB/T 7714	Pan, An-Peng,Wen, Li-Jin,Shao, Xu,et al. A novel ophthalmic viscosurgical device-free phakic intraocular lens implantation makes myopic surgery safer[J]. EYE AND VISION,2020,7(1):18.
APA	Pan, An-Peng., Wen, Li-Jin., Shao, Xu., Zhou, Kai-Jing., Wang, Qin-Mei., ... & Yu, A-Yong. (2020). A novel ophthalmic viscosurgical device-free phakic intraocular lens implantation makes myopic surgery safer. EYE AND VISION, 7(1), 18.
MLA	Pan, An-Peng,et al."A novel ophthalmic viscosurgical device-free phakic intraocular lens implantation makes myopic surgery safer".EYE AND VISION 7.1(2020):18.