Intensivists' response to hyperoxemia in mechanical ventilation patients:The status quo and related factors

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题名	Intensivists' response to hyperoxemia in mechanical ventilation patients:The status quo and related factors
作者	Zi-wei Ke ; Yue Jiang ; Ya-ping Bao ; Ye-qin Yang ; Xiao-mei Zong ; Min Liu ; Xiang-yun Guan ; Zhong-qiu Lu
发表日期	2021-06-23
发表期刊	World Journal of Emergency Medicine 影响因子和分区
语种	英语
关键词	Mechanical ventilation Hyperoxemia Fraction of inspired oxygen Arterial blood gas Intensive care unit
摘要	BACKGROUND:Due to the still sparse literature in China,the investigation of hyperoxemia management is required.Thus,we aim to conduct a retrospective study to provide more information about hyperoxemia management in intensive care unit(ICU) patients.METHODS:We retrospectively screened the medical records of adult patients(age ≥18 years)who required mechanical ventilation(MV)≥24 hours from January 1,2018,to December 31,2018.All arterial blood gas(ABG) tested during MV was retrieved,and MV settings were recorded.The median arterial partial pressure of oxygen(PaO_2)≥120 mmHg(1 mmHg=0.133 kPa) was defined as mild to moderate hyperoxemia,and PaO_2>300 mmHg as extreme hyperoxemia.Intensivists' response to hyperoxemia was assessed based on the reduction of fraction of inspired oxygen(FiO_2) within one hour after hyperoxemia was recorded.Multivariable logistic regression analysis was performed to determine the independent factors associated with the intensivists' response to hyperoxemia.RESULTS:A total of 592 patients were finally analyzed.The median Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ) score was 21(15-26).The PaO_2,arterial oxygen saturation(SaO_2),FiO_2,and positive end expiratory pressure(PEEP) were 96.4(74.0-126.0) mmHg,97.8%(95.2%-99.1%),0.4(0.4-0.5),and 5(3-6) cmH_2 O,respectively.Totally 174(29.39%) patients had PaO_2>120 mmHg,and 19(3.21%) patients had extreme hyperoxemia at PaO_2>300 mmHg.In cases of mild to moderate hyperoxemia with FiO_2 ≤0.4,only 13(2.20%) patients had a decrease in FiO_2 within one hour.The multivariable logistic regression analysis showed that a positive response was independently associated with FiO_2(odds ratio [OR] 1.09,95% confidence interval [CI] 1.06-1.12,P
ISSN	1920-8642
卷号	12 期号:03 页码:202-206
收录类别	CNKI
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/134198
专题	附属第一医院护理学院其他_附属义乌医院（义乌市中心医院）
作者单位	1.Department of Emergency Medicine, the First Affiliated Hospital of Wenzhou Medical University 2.Department of Nursing, Taizhou Hospital of Zhejiang Province 3.Operating Room, the First Affiliated Hospital of Wenzhou Medical University 4.Faculty of Nursing, Wenzhou Medical University 5.Yiwu Hospital Affiliated to Wenzhou Medical University
推荐引用方式 GB/T 7714	Zi-wei Ke,Yue Jiang,Ya-ping Bao,et al. Intensivists' response to hyperoxemia in mechanical ventilation patients:The status quo and related factors[J]. World Journal of Emergency Medicine,2021,12(03):202-206.
APA	Zi-wei Ke., Yue Jiang., Ya-ping Bao., Ye-qin Yang., Xiao-mei Zong., ... & Zhong-qiu Lu. (2021). Intensivists' response to hyperoxemia in mechanical ventilation patients:The status quo and related factors. World Journal of Emergency Medicine, 12(03), 202-206.
MLA	Zi-wei Ke,et al."Intensivists' response to hyperoxemia in mechanical ventilation patients:The status quo and related factors".World Journal of Emergency Medicine 12.03(2021):202-206.

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