The Predictive Value of the Follicular Output Rate on Pregnancy Outcome of Patients with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization and Embryo Transfer

doi:10.12659/MSM.916175

科研成果详情

题名	The Predictive Value of the Follicular Output Rate on Pregnancy Outcome of Patients with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization and Embryo Transfer
作者	Yang, Haiyan; Lin, Jia; Jin, Congcong; Meng, Lvhe; Wu, Suichun; Chen, Ya
发表日期	2020-12-11
发表期刊	MEDICAL SCIENCE MONITOR 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Embryo Transfer Pregnancy Complications Reproductive Techniques, Assisted
其他关键词	ANTI-MULLERIAN HORMONE ; STIMULATING-HORMONE ; ANTIMULLERIAN HORMONE ; RATE FORT ; WOMEN ; SERUM ; INFERTILITY ; IVF/ICSI ; IVF
摘要	Background: This retrospective study aimed to evaluate the predictive value of the follicular output rate (FORT) on the pregnancy outcome of patients with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization and embryo transfer (IVF-ET). Material/Methods: Between January 2012 and June 2016, a total of 1,541 patients with PCOS who underwent IVF-ET at our center were enrolled in the study. FORT was calculated as the pre-ovulatory follicle count (PFC)/antral follicle count (AFC) x 100%. Results: According to the FORT, patients were divided into low, medium, and high FORT groups. With an increase in the FORT, the PFC and serum estradiol at the day of human chorionic gonadotropin (hCG) injection, the number of retrieved oocytes, metaphase II (MII) oocytes, total number of embryos, and number of high-quality embryos significantly increased (P<0.05 and P<0.001) from the low to high FORT groups, while the AFC, gonadotropin (Gn) stimulation day, and total Gn decreased significantly (P<0.001). The live birth rate from frozen embryo transfer and the cumulative live birth rate was the lowest in middle FORT group but increased significantly in high FORT group (P<0.05). The correlation analysis between FORT and related factors showed that the FORT was negatively correlated with body mass index (BMI), Gn stimulation days, and total Gn (P<0.05). Conclusions: FORT is a powerful tool for measuring ovarian reactivity. For patients with PCOS, a high FORT to obtain high-quality embryos and perform frozen embryo transplantation can achieve good pregnancy outcome.
出版者	INT SCIENTIFIC INFORMATION, INC
出版地	MELVILLE
ISSN	1643-3750
EISSN	1643-3750
卷号	26 页码:e916175.
DOI	10.12659/MSM.916175
页数	9
WOS类目	Medicine, Research & Experimental
WOS研究方向	Research & Experimental Medicine
WOS记录号	WOS:000597310800001
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	33306667
PMC记录号	PMC7737407
SCOPUSEID	2-s2.0-85097625202
通讯作者地址	[Chen, Ya]Reproductive Medicine Center,The First Affiliated Hospital,Wenzhou Medical University,Wenzhou, Zhejiang,China
Scopus学科分类	Medicine (all)
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/12778
专题	第一临床医学院（信息与工程学院）、附属第一医院附属第一医院
通讯作者	Chen, Ya
作者单位	Reproductive Medicine Center,The First Affiliated Hospital,Wenzhou Medical University,Wenzhou, Zhejiang,China
第一作者单位	第一临床医学院（信息与工程学院）、附属第一医院; 附属第一医院
通讯作者单位	第一临床医学院（信息与工程学院）、附属第一医院; 附属第一医院
第一作者的第一单位	第一临床医学院（信息与工程学院）、附属第一医院; 附属第一医院
推荐引用方式 GB/T 7714	Yang, Haiyan,Lin, Jia,Jin, Congcong,et al. The Predictive Value of the Follicular Output Rate on Pregnancy Outcome of Patients with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization and Embryo Transfer[J]. MEDICAL SCIENCE MONITOR,2020,26:e916175..
APA	Yang, Haiyan, Lin, Jia, Jin, Congcong, Meng, Lvhe, Wu, Suichun, & Chen, Ya. (2020). The Predictive Value of the Follicular Output Rate on Pregnancy Outcome of Patients with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization and Embryo Transfer. MEDICAL SCIENCE MONITOR, 26, e916175..
MLA	Yang, Haiyan,et al."The Predictive Value of the Follicular Output Rate on Pregnancy Outcome of Patients with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization and Embryo Transfer".MEDICAL SCIENCE MONITOR 26(2020):e916175..