T-helper 17 cell: A distinctive cell in liver diseases

doi:10.1111/j.1872-034X.2010.00744.x

科研成果详情

题名	T-helper 17 cell: A distinctive cell in liver diseases
作者	Ye, Chao; Li, Wen-yuan; Zheng, Ming-hua; Chen, Yong-ping
发表日期	2011-01
发表期刊	HEPATOLOGY RESEARCH 影响因子和分区
语种	英语
原始文献类型	Review
关键词	autoimmune inflammatory liver regulatory T cell T-helper 17 cell
其他关键词	PRIMARY BILIARY-CIRRHOSIS ; GROWTH-FACTOR-BETA ; TH17 CELLS ; TGF-BETA ; INTERLEUKIN-17 PRODUCTION ; RHEUMATOID-ARTHRITIS ; CYTOKINE PROFILE ; IMMUNE-RESPONSE ; INNATE IMMUNITY ; ACUTE REJECTION
摘要	T-helper (Th)17 cells, a new population of effector CD4+ T cells, are characterized by the secretion of interleukin (IL)-17. It has been demonstrated that Th17 cells are distinct from Th1 and Th2 cells; they play important roles in the pathogenesis of numerous inflammatory and autoimmune diseases; and are closely related to host defense, tumorigenesis and transplant rejection. Moreover, it has been found that these cells have a close and intricate connection with the regulatory T cells, which play an important role in maintaining self-tolerance and down-tuning immune responses. In the present review, we find that they are significantly elevated in various kinds of liver diseases including liver autoimmunity and inflammatory diseases, alcoholic liver disease and hepatocellular carcinoma.
资助项目	Zhejiang Provincial Natural Science Foundation of ChinaNatural Science Foundation of Zhejiang Province [Y207464]; Scientific Research Foundation of Wenzhou, Zhejiang Province, China [H20090014, Y20090269]; Research Foundation of Education Bureau of Zhejiang Province [Y201009942]; Health Bureau of Zhejiang Province [2010KYB070]
出版者	WILEY
出版地	HOBOKEN
ISSN	1386-6346
EISSN	1872-034X
卷号	41 期号:1 页码:22-29
DOI	10.1111/j.1872-034X.2010.00744.x
页数	8
WOS类目	Gastroenterology & Hepatology
WOS研究方向	Gastroenterology & Hepatology
WOS记录号	WOS:000285783200002
收录类别	SCIE ; PUBMED
URL	查看原文
PubMed ID	21108703
通讯作者地址	[Chen, Yong-ping]Affiliated Hosp 1, Wenzhou Med Coll, Dept Infect & Liver Dis, Liver Res Ctr, 2 Fuxue Lane, Wenzhou 325000, Zhejiang, Peoples R China.
引用统计	被引频次：18[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/12359
专题	第一临床医学院（信息与工程学院）、附属第一医院_内科学_感染内科附属第一医院
通讯作者	Chen, Yong-ping
作者单位	Affiliated Hosp 1, Wenzhou Med Coll, Dept Infect & Liver Dis, Liver Res Ctr, Wenzhou 325000, Zhejiang, Peoples R China
第一作者单位	附属第一医院; 感染内科
通讯作者单位	附属第一医院; 感染内科
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Ye, Chao,Li, Wen-yuan,Zheng, Ming-hua,et al. T-helper 17 cell: A distinctive cell in liver diseases[J]. HEPATOLOGY RESEARCH,2011,41(1):22-29.
APA	Ye, Chao, Li, Wen-yuan, Zheng, Ming-hua, & Chen, Yong-ping. (2011). T-helper 17 cell: A distinctive cell in liver diseases. HEPATOLOGY RESEARCH, 41(1), 22-29.
MLA	Ye, Chao,et al."T-helper 17 cell: A distinctive cell in liver diseases".HEPATOLOGY RESEARCH 41.1(2011):22-29.