Surgical treatment of 19 cases with vibrio necrotising fasciitis

doi:10.1016/j.burns.2011.04.013

科研成果详情

题名	Surgical treatment of 19 cases with vibrio necrotising fasciitis
作者	Hong, Guang-Liang; Lu, Cai-Jiao; Lu, Zhong-Qiu; Li, Meng-Fang; Qiu, Qiao-Meng; Liang, Huan; Wu, Bin
发表日期	2012-03
发表期刊	BURNS 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Vibrio necrotising fasciitis Treatment Surgical indications Emergency Incision and drainage
其他关键词	SOFT-TISSUE INFECTIONS ; VULNIFICUS ; DIAGNOSIS ; NON-O1 ; TAIWAN
摘要	Background: Necrotising fasciitis and sepsis caused by the infection of vibrio is a rare but dangerous clinical emergency, with a mortality of 50-100%. Early diagnosis and surgical treatment may improve the prognosis significantly. However, valid emergency operation indications are scarce and need to be explored, which will be helpful for the early recognition and selection of operational procedures in patients with vibrio necrotising fasciitis. Methods: We retrospectively analysed the patients with vibrio necrotising fasciitis admitted to the emergency department of our hospital from July 2000 to June 2009. The surgical treatment strategy was summarised in order to provide clinical evidence for surgical treatment of vibrio necrotising fasciitis. Results: A total of 19 cases of vibrio necrotising fasciitis were selected in our study. All the patients were living along the coast, and 68.4% had a history of chronic liver disease, 78.9% had a history of ethanol abuse, 52.6% had fever, 89.5% were complicated with septic shock and 31.6% progressed to multiple-organ dysfunction syndrome. Rapidly progressive local swelling and pain as well as skin superficial venous stasis were the early presentations of vibrio necrotising fasciitis, while skin ecchymosis, blisters or blood blisters, necrosis and subcutaneous crepitation were the presentations of the advanced stage. Seventeen patients received emergency incision and drainage, subcutaneous vein thrombosis, subcutaneous tissue necrosis, muscle and full-thickness necrosis observed in the operation, and necrotising fasciitis was confirmed by exploration or pathologic examination. Selective debridement and skin graft was performed to repair the wound after operation, and amputation was performed on two patients to close the wound. The average length of stay was 21.3 days (1-82 days), and eight patients died, with mortality being 42.1%. Conclusion: Rapidly progressive local damage and acute deterioration of the patients are the most distinctive clinical manifestations of vibrio necrotising fasciitis. Recognition of the signs of local skin and tissue damage in early stage is crucial for early diagnosis and surgical intervention. Emergency incision and drainage, combined with selective debridement and skin graft, could improve the prognosis of the patients, and preserve the integrity of the patient's limbs as much as possible. (C) 2011 Elsevier Ltd and ISBI. All rights reserved.
资助项目	key construction academic subject (medicine) of Zhejiang Province [07-F04]
出版者	ELSEVIER SCI LTD
出版地	OXFORD
ISSN	0305-4179
EISSN	1879-1409
卷号	38 期号:2 页码:290-295
DOI	10.1016/j.burns.2011.04.013
页数	6
WOS类目	Critical Care Medicine ; Dermatology ; Surgery
WOS研究方向	General & Internal Medicine ; Dermatology ; Surgery
WOS记录号	WOS:000301621500020
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	22103992
SCOPUSEID	2-s2.0-84857457930
通讯作者地址	[Lu, Zhong-Qiu]Wenzhou Med Coll, Affiliated Hosp 1, Dept Emergency Med, 2 Fuxue Lane, Wenzhou 325000, Zhejiang, Peoples R China.
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/12176
专题	第一临床医学院（信息与工程学院）、附属第一医院_急诊医学
通讯作者	Lu, Zhong-Qiu
作者单位	Wenzhou Med Coll, Affiliated Hosp 1, Dept Emergency Med, Wenzhou 325000, Zhejiang, Peoples R China
第一作者单位	第一临床医学院（信息与工程学院）、附属第一医院_急诊医学
通讯作者单位	第一临床医学院（信息与工程学院）、附属第一医院_急诊医学
第一作者的第一单位	第一临床医学院（信息与工程学院）、附属第一医院_急诊医学
推荐引用方式 GB/T 7714	Hong, Guang-Liang,Lu, Cai-Jiao,Lu, Zhong-Qiu,et al. Surgical treatment of 19 cases with vibrio necrotising fasciitis[J]. BURNS,2012,38(2):290-295.
APA	Hong, Guang-Liang., Lu, Cai-Jiao., Lu, Zhong-Qiu., Li, Meng-Fang., Qiu, Qiao-Meng., ... & Wu, Bin. (2012). Surgical treatment of 19 cases with vibrio necrotising fasciitis. BURNS, 38(2), 290-295.
MLA	Hong, Guang-Liang,et al."Surgical treatment of 19 cases with vibrio necrotising fasciitis".BURNS 38.2(2012):290-295.