Ten Years of EWAS

doi:10.1002/advs.202100727

科研成果详情

题名	Ten Years of EWAS
作者	Wei, Siyu 1,2; Tao, Junxian 1,2; Xu, Jing 1,2; Chen, Xingyu 1; Wang, Zhaoyang 1; Zhang, Nan 1; Zuo, Lijiao 1; Jia, Zhe 1; Chen, Haiyan 1; Sun, Hongmei 1; Yan, Yubo 1; Zhang, Mingming 1; Lv, Hongchao 1; Kong, Fanwu 2,3; Duan, Lian2,4; Ma, Ye 1,2; Liao, Mingzhi 2,5; Xu, Liangde2,6; Feng, Rennan 2,7; Liu, Guiyou 2,8; Project, The EWAS 2; Jiang, Yongshuai 1,2
发表日期	2021-10
发表期刊	ADVANCED SCIENCE 影响因子和分区
语种	英语
原始文献类型	Review
关键词	epigenome-wide association study (EWAS) epigenetics DNA methylation
其他关键词	EPIGENOME-WIDE ASSOCIATION ; DNA METHYLATION ANALYSIS ; BODY-MASS INDEX ; ALZHEIMERS-DISEASE ; METABOLIC SYNDROME ; RHEUMATOID-ARTHRITIS ; PERIPHERAL-BLOOD ; R PACKAGE ; EPIGENETIC MODIFICATION ; NORMALIZATION METHOD
摘要	Epigenome-wide association study (EWAS) has been applied to analyze DNA methylation variation in complex diseases for a decade, and epigenome as a research target has gradually become a hot topic of current studies. The DNA methylation microarrays, next-generation, and third-generation sequencing technologies have prepared a high-quality platform for EWAS. Here, the progress of EWAS research is reviewed, its contributions to clinical applications, and mainly describe the achievements of four typical diseases. Finally, the challenges encountered by EWAS and make bold predictions for its future development are presented.
资助项目	Mathematical Tianyuan Fund of the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [12026414]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [92046018, 31970651]; Innovation and Entrepreneurship Training Program for College Students of Heilongjiang Province [S202010226092X]
出版者	WILEY
出版地	HOBOKEN
ISSN	2198-3844
EISSN	2198-3844
卷号	8 期号:20 页码:e2100727.
DOI	10.1002/advs.202100727
页数	215
WOS类目	Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science
WOS记录号	WOS:000684087200001
收录类别	SCIE ; PUBMED ; EI ; SCOPUS
EI入藏号	20213310764119
EI主题词	Clinical research
URL	查看原文
PubMed ID	34382344
PMC记录号	PMC8529436
SCOPUSEID	2-s2.0-85112303592
自科自定义期刊分类	T3(B)类
通讯作者地址	[Jiang, Yongshuai]College of Bioinformatics Science and Technology,Harbin Medical University,Harbin,150081,China
Scopus学科分类	Medicine (miscellaneous);Chemical Engineering (all);Materials Science (all);Biochemistry, Genetics and Molecular Biology (miscellaneous);Engineering (all);Physics and Astronomy (all)
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/10562
专题	附属第一医院眼视光学院（生物医学工程学院）、附属眼视光医院仁济学院_眼视光、生物医学工程学部
通讯作者	Jiang, Yongshuai
作者单位	1.College of Bioinformatics Science and Technology,Harbin Medical University,Harbin,150081,China; 2.The EWAS Project,Harbin,China; 3.Department of Nephrology,The Second Affiliated Hospital,Harbin Medical University,Harbin,150001,China; 4.The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,325000,China; 5.College of Life Sciences,Northwest A&F University,Yangling,712100,China; 6.School of Biomedical Engineering,Wenzhou Medical University,Wenzhou,325035,China; 7.Department of Nutrition and Food Hygiene,Public Health College,Harbin Medical University,Harbin,150081,China; 8.Beijing Institute for Brain Disorders,Capital Medical University,Beijing,100069,China
推荐引用方式 GB/T 7714	Wei, Siyu,Tao, Junxian,Xu, Jing,et al. Ten Years of EWAS[J]. ADVANCED SCIENCE,2021,8(20):e2100727..
APA	Wei, Siyu., Tao, Junxian., Xu, Jing., Chen, Xingyu., Wang, Zhaoyang., ... & Jiang, Yongshuai. (2021). Ten Years of EWAS. ADVANCED SCIENCE, 8(20), e2100727..
MLA	Wei, Siyu,et al."Ten Years of EWAS".ADVANCED SCIENCE 8.20(2021):e2100727..